Nature Search

Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition

The BTK inhibitor ibrutinib is used to treat chronic lymphocytic leukaemia, however some patients develop resistance to the drug. Here, the authors use genomic analyses to examine the clonal evolution of 5 patients that develop resistance to ibrutinib.

Jan A. Burger
Dan A. Landau
Catherine J. Wu
ResearchOpen Access20 May 2016
Nature Communications

Volume: 7, P: 1-13
Metal telluride nanosheets by scalable solid lithiation and exfoliation

Fast and scalable synthesis of a variety of transition metal telluride nanosheets by solid lithiation and hydrolysis is demonstrated and several interesting quantum phenomena were observed, such as quantum oscillations and giant magnetoresistance.

Liangzhu Zhang
Zixuan Yang
Hui-Ming Cheng
Research03 Apr 2024
Nature

Volume: 628, P: 313-319
Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders

For many neurodevelopmental disorder (NDD) risk genes, the significance for mutational burden is unestablished. Here, the authors sequence 125 candidate NDD genes in over 16,000 NDD cases; case-control mutational burden analysis identifies 48 genes with a significant burden of severe ultra-rare mutations.

Tianyun Wang
Kendra Hoekzema
Evan E. Eichler
ResearchOpen Access01 Oct 2020
Nature Communications

Volume: 11, P: 1-13
De novo genic mutations among a Chinese autism spectrum disorder cohort

Recurrent sporadic mutations are important risk factors for autism spectrum disorders (ASDs) but have been primarily investigated in European cohorts. Here, Eichler, Xia and colleagues analyse risk genes in a large Chinese ASD cohort and find novel recurrences of potential pathogenic significance.

Tianyun Wang
Hui Guo
Evan E. Eichler
ResearchOpen Access08 Nov 2016
Nature Communications

Volume: 7, P: 1-10
Multiparameter diagnostic model using S100A9, CCL5 and blood biomarkers for nasopharyngeal carcinoma

Lu Long
Ya Tao
Bin Yi
ResearchOpen Access03 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
Author Correction: Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders

Tianyun Wang
Kendra Hoekzema
Evan E. Eichler
Amendments and CorrectionsOpen Access21 Oct 2020
Nature Communications

Volume: 11, P: 1
AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders

Genetic variants in ionotropic glutamate receptors have been implicated in neurodevelopmental disorders. Here, the authors report heterozygous de novo mutations in the GRIA2 gene in 28 individuals with intellectual disability and neurodevelopmental abnormalities associated with reduced Ca²⁺ transport and AMPAR currents.”

Vincenzo Salpietro
Christine L. Dixon
Henry Houlden
ResearchOpen Access12 Jul 2019
Nature Communications

Volume: 10, P: 1-16
Setd2 supports GATA3⁺ST2⁺ thymic-derived Treg cells and suppresses intestinal inflammation

Treg cells can be functionally altered by epigenetic modulators. Here the authors show that the histone H3K36 methyltransferase Setd2 is important for the survival of Treg cells and for the regulation of IL-33 mediated Th2 responses in mice and SETD2 expression is increased in Treg cells from human colorectal cancer tissue.

Zhaoyun Ding
Ting Cai
Ju Qiu
ResearchOpen Access03 Dec 2022
Nature Communications

Volume: 13, P: 1-19
Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders

Neurodevelopmental disorders (NDDs) are a heterogeneous group of diseases for which the genetic basis is still unknown in more than half of the cases. Here, the authors report a NDD associated with disruptive variants in the TANC2 gene and show that rols, the TANC2 homolog in flies, is required for synapse growth and function.

Hui Guo
Elisa Bettella
Evan E. Eichler
ResearchOpen Access15 Oct 2019
Nature Communications

Volume: 10, P: 1-17
Analysis of changes in nutritional compounds of dried yellow chili after different processing treatments

Ruihao Zhang
Junheng Lv
Minghua Deng
ResearchOpen Access16 Sept 2024
Scientific Reports

Volume: 14, P: 1-15
Efficacy of atosiban for repeated implantation failure in frozen embryo transfer cycles

Xiufang Li
Yanbo Du
Qingfeng Lian
ResearchOpen Access07 Jun 2023
Scientific Reports

Volume: 13, P: 1-7
The preliminary in vitro study and application of deep learning algorithm in cone beam computed tomography image implant recognition

Shaobo Ou-yang
Shuqin Han
Lan Liao
ResearchOpen Access27 Oct 2023
Scientific Reports

Volume: 13, P: 1-10
Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulation

Xiaoying Lan
Chong Zhao
Jinbao Liu
ResearchOpen Access06 Jul 2017
Cell Death & Disease

Volume: 8, P: e2913

Search

Clonal evolution in patients with chronic lymphocytic leukaemia developing resistance to BTK inhibition

Metal telluride nanosheets by scalable solid lithiation and exfoliation

Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders

De novo genic mutations among a Chinese autism spectrum disorder cohort

Multiparameter diagnostic model using S100A9, CCL5 and blood biomarkers for nasopharyngeal carcinoma

Author Correction: Large-scale targeted sequencing identifies risk genes for neurodevelopmental disorders

AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders

Setd2 supports GATA3⁺ST2⁺ thymic-derived Treg cells and suppresses intestinal inflammation

Disruptive mutations in TANC2 define a neurodevelopmental syndrome associated with psychiatric disorders

Analysis of changes in nutritional compounds of dried yellow chili after different processing treatments

Efficacy of atosiban for repeated implantation failure in frozen embryo transfer cycles

The preliminary in vitro study and application of deep learning algorithm in cone beam computed tomography image implant recognition

Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulation

Search

Quick links

Search

Filter By:

Search

Quick links