Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

View all journals
Search
Log in

nature
search

Search

Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Nature (3)
Scientific Reports (1)

Choose more journals

Article type Check one or more article types to show results from those article types only.

Research (4)

Subject Check one or more subjects to show results from those subjects only.

Biochemistry
Biotechnology
Cancer
Computational biology and bioinformatics
Medical research

Date Choose a date option to show results from those dates only.

Today
Last 7 days
Last 30 days
Last 12 months
Last 2 years
Last 5 years

Custom date range

Clear all filters

Sort by:

Relevance

Date published (new to old)

Date published (old to new)

Showing 1–4 of 4 results

Advanced filters: Author: Isaac Sappington Clear advanced filters

De novo designed proteins neutralize lethal snake venom toxins

Deep learning methods have been used to design proteins that can neutralize the effects of three-finger toxins found in snake venom, which could lead to the development of safer and more accessible antivenom treatments.

Susana Vázquez Torres
Melisa Benard Valle
David Baker
ResearchOpen Access15 Jan 2025
Nature

Volume: 639, P: 225-231
Designed endocytosis-inducing proteins degrade targets and amplify signals

Computationally designed genetically encoded proteins can be used to target surface proteins, thereby triggering endocytosis and subsequent intracellular degradation, activating signalling or increasing cellular uptake in specific tissues.

Buwei Huang
Mohamad Abedi
David Baker
ResearchOpen Access25 Sept 2024
Nature

Volume: 638, P: 796-804
De novo design of protein structure and function with RFdiffusion

Fine-tuning the RoseTTAFold structure prediction network on protein structure denoising tasks yields a generative model for protein design that achieves outstanding performance on a wide range of protein structure and function design challenges.

Joseph L. Watson
David Juergens
David Baker
ResearchOpen Access11 Jul 2023
Nature

Volume: 620, P: 1089-1100
A Radiosensitizing Inhibitor of HIF-1 alters the Optical Redox State of Human Lung Cancer Cells In Vitro

David E. Lee
Kinan Alhallak
Narasimhan Rajaram
ResearchOpen Access11 Jun 2018
Scientific Reports

Volume: 8, P: 1-10