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Advanced filters: Author: Jade Clarson Clear advanced filters

  • The success of CAR-T cells for treating acute myeloid leukaemia (AML) is hampered by toxicity to normal cells and low CAR-T cell persistence. Here, the authors show that the demethylating compound 5′-Azacitdine increases anti-CD123 CAR-T cell cytotoxicity against AML.

    • Nadia El Khawanky
    • Amy Hughes
    • Robert Zeiser
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-20