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Advanced filters: Author: Jennifer Mattera Clear advanced filters

  • Examination of predicted loss-of-function (pLOF) genetic variants allows direct identification of genes with therapeutic potential. Here, Emdin et al. perform association analysis for 3759 pLOF variants with 24 traits and highlight protective variants against cardiometabolic and immune phenotypes.

    • Connor A. Emdin
    • Amit V. Khera
    • Sekar Kathiresan
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-8