The effects of statin treatment on the development of cognitive impairment, dementia and Alzheimer disease are unclear. In this Review, the authors systematically evaluate the findings from randomized controlled trials and observational studies that have investigated the association of statin use with cognition—including consideration of probable sources of bias—so as to summarize the current evidence and make recommendations for future work.
- Melinda C. Power
- Jennifer Weuve
- Rebecca F. Gottesman
