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Scientific Reports (11)
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Showing 1–50 of 54 results

Advanced filters: Author: Jiahong Chen Clear advanced filters

Inhibiting defect passivation failure in perovskite for perovskite/Cu(In,Ga)Se₂ monolithic tandem solar cells with certified efficiency 27.35%

Pei et al. overcome desorption of passivating molecules under photothermal stress in wide-bandgap perovskites and achieve perovskite/Cu(In,Ga)Se₂ tandem solar cells with a certified efficiency of 27.35%.

Fengtao Pei
Shuping Lin
Qi Chen
Research30 Jun 2025
Nature Energy

P: 1-12
VCL/ICAM-1 pathway is associated with lung inflammatory damage in SARS-CoV-2 Omicron infection

Here, the authors performed plasma proteomics and metabolomics analysis and identify the vinculin (VCL) pathway as a key mediator of lung exudation in SARS-CoV-2 infections, particularly associated with Omicron infection. In a mouse model of infection inhibition of VCL leads to reduced lung pathology.

Mingshan Xue
Zhiwei Lin
Baoqing Sun
ResearchOpen Access23 Apr 2025
Nature Communications

Volume: 16, P: 1-19
Engineered circular guide RNAs enhance miniature CRISPR/Cas12f-based gene activation and adenine base editing

The compact Cas12f enzyme exhibits obvious delivery advantage for gene editing, but its activity remains suboptimal. Here, the authors have designed and optimized circular guide RNA (cgRNA) for Cas12f, which significantly improves the efficiency of gene activation and adenine base editing.

Xin Zhang
Mengrao Li
Zhili Rong
ResearchOpen Access28 Mar 2025
Nature Communications

Volume: 16, P: 1-9
Author Correction: Evolution and expression patterns of the neo-sex chromosomes of the crested ibis

Lulu Xu
Yandong Ren
Gang Li
Amendments and CorrectionsOpen Access28 Oct 2024
Nature Communications

Volume: 15, P: 1
Lysosomal-associated protein transmembrane 5 ameliorates non-alcoholic steatohepatitis by promoting the degradation of CDC42 in mice

Non-alcoholic steatohepatitis (NASH) has received great attention due to its high incidence, but the underlying mechanism remains poorly understood. Here, the authors show LAPTM5 expression ameliorates NASH and can potentially serve as a biological marker indicative of NASH progression.

Lang Jiang
Jing Zhao
Jiahong Xia
ResearchOpen Access08 May 2023
Nature Communications

Volume: 14, P: 1-16
Knowledge, attitude and practice of rehabilitation management of the caregivers of pediatric patients with hemiplegia

Ya Guo
Xiaoli Li
Yuanyuan Lai
ResearchOpen Access28 May 2025
Scientific Reports

Volume: 15, P: 1-9
IDH1 mutation impairs antiviral response and potentiates oncolytic virotherapy in glioma

The role of human glioma IDH1 mutations in regulation of antiviral response is unclear. Here, the authors show that D2HG produced by mutant IDH1 inhibits IFN antiviral responses in glioma cells, which confers sensitivity to oncolytic virotherapy.

Xueqin Chen
Jun Liu
Haipeng Zhang
ResearchOpen Access25 Oct 2023
Nature Communications

Volume: 14, P: 1-15
Phase-separated porous nanocomposite with ultralow percolation threshold for wireless bioelectronics

An in situ phase-separation method at microscale level creates stretchable superelastic porous nanocomposite conductors, reduces conductive filler usage and enables strain-resilient wireless wearable and implantable bioelectronics.

Yadong Xu
Zhilu Ye
Zheng Yan
Research29 Apr 2024
Nature Nanotechnology

Volume: 19, P: 1158-1167
Evolution and expression patterns of the neo-sex chromosomes of the crested ibis

The evolutionary trajectory of avian sex chromosomes may be more intricate than previously understood. In this study, sequencing and analysis of the neo-sex chromosomes and genome of the Crested Ibis suggests a multidirectional evolution of sex chromosomes in core waterbirds.

Lulu Xu
Yandong Ren
Gang Li
ResearchOpen Access23 Feb 2024
Nature Communications

Volume: 15, P: 1-14
CD276-dependent efferocytosis by tumor-associated macrophages promotes immune evasion in bladder cancer

Tumor associated macrophages (TAM) are playing an active role in tumor immune evasion in multiple cancer type. Here authors show that CD276 expression by TAMs may underpin this immune-suppressive role via promoting efferocytosis and suppressing MHC class II expression, which result in decreased CD4+ and CD8 + T cell infiltration.

Maosheng Cheng
Shuang Chen
Liang Peng
ResearchOpen Access01 Apr 2024
Nature Communications

Volume: 15, P: 1-17
Heterologous AD5-nCOV plus CoronaVac versus homologous CoronaVac vaccination: a randomized phase 4 trial

Heterologous vaccination with Convidecia, a recombinant adenovirus type 5-vectored COVID-19 vaccine, after one or two doses of CoronaVac, an inactivated SARS-CoV-2 vaccine, is more reactogenic but elicits significantly higher levels of neutralizing antibodies than homologous vaccination.

Jingxin Li
Lihua Hou
Fengcai Zhu
ResearchOpen Access27 Jan 2022
Nature Medicine

Volume: 28, P: 401-409
The mitochondrial genome and phylogenetic analysis of Rhacophorus rhodopus

Wei Chen
Haifen Qin
Buddhi Dayananda
ResearchOpen Access11 Aug 2022
Scientific Reports

Volume: 12, P: 1-10
Inhibition of intimal hyperplasia in murine aortic allografts by administration of a small-molecule TLR4 inhibitor TAK-242

Chuangyan Wu
Xiangchao Ding
Jiahong Xia
ResearchOpen Access17 Nov 2017
Scientific Reports

Volume: 7, P: 1-11
A wireless patch for the monitoring of C-reactive protein in sweat

A wearable electrochemical patch for the real-time monitoring of the biomarker C-reactive protein in sweat detects elevated concentrations of the protein in patients with acute or chronic inflammation.

Jiaobing Tu
Jihong Min
Wei Gao
Research22 Jun 2023
Nature Biomedical Engineering

Volume: 7, P: 1293-1306
Autophagy induction promoted by m⁶A reader YTHDF3 through translation upregulation of FOXO3 mRNA

The role of eiptranscriptomic modifications in autophagy is unclear. Here, the authors show that the m⁶A reader YTHDF3 functions as a nutrient responder to recognize upregulated m⁶A modification, promoting FOXO3 translation to subsequently initiate autophagy.

WeiChao Hao
MeiJuan Dian
Dong Xiao
ResearchOpen Access04 Oct 2022
Nature Communications

Volume: 13, P: 1-23
Large local lattice expansion in graphene adlayers grown on copper

Angle-resolved photoemission spectroscopy with nanometre spatial resolution and low-energy electron microscopy/diffraction reveal that interaction with the Cu substrate can induce up to 7.5% lattice expansion in graphene adlayers.

Chaoyu Chen
José Avila
Maria C. Asensio
Research09 Apr 2018
Nature Materials

Volume: 17, P: 450-455
ABRO1 suppresses tumourigenesis and regulates the DNA damage response by stabilizing p53

The scaffold protein Abraxas brother 1 (ABRO1) accumulates in the nucleus after oxidative stress but its role in cellular responses to DNA damage has not been elucidated. Here the authors show that ABRO1 exerts its tumour suppressor activity by regulating p53 stability via USP7 deubiquitinase.

Jianhong Zhang
Mengmeng Cao
Xiaoming Yang
ResearchOpen Access06 Oct 2014
Nature Communications

Volume: 5, P: 1-15
Abnormal cGMP-dependent protein kinase I-mediated decidualization in preeclampsia

Jingsi Chen
Wenlu Ren
Lili Du
Research23 Oct 2020
Hypertension Research

Volume: 44, P: 318-324
Retraction Note: Large local lattice expansion in graphene adlayers grown on copper

Chaoyu Chen
José Avila
Maria C. Asensio
Amendments and Corrections27 Sept 2018
Nature Materials

Volume: 17, P: 1048
RNF115 deletion inhibits autophagosome maturation and growth of gastric cancer

Riyong Li
Zhaohui Gu
Yingyu Chen
ResearchOpen Access26 Sept 2020
Cell Death & Disease

Volume: 11, P: 1-9
GNE myopathy in Chinese population: hotspot and novel mutations

Yang Chen
Jianying Xi
Jiahong Lu
Research02 Nov 2018
Journal of Human Genetics

Volume: 64, P: 11-16
p53 attenuates acetaminophen-induced hepatotoxicity by regulating drug-metabolizing enzymes and transporter expression

Jiahong Sun
Yajie Wen
Huichang Bi
ResearchOpen Access10 May 2018
Cell Death & Disease

Volume: 9, P: 1-12
Improving model performance in mapping black-soil resource with machine learning methods and multispectral features

Jianfang Hu
Yulei Tang
Zhansheng Chen
ResearchOpen Access07 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
Experimental study on the influence of lapping plate materials on the quality of both sides cylindrical rollers machining

Tianchen Zhao
Jiahong Ruan
Xiaoliang Jiang
ResearchOpen Access13 Jan 2025
Scientific Reports

Volume: 15, P: 1-21
TMEM189 negatively regulates the stability of ULK1 protein and cell autophagy

Jiahong Yu
Liujing Qu
Yingyu Chen
ResearchOpen Access07 Apr 2022
Cell Death & Disease

Volume: 13, P: 1-10
Annexin A1 binds PDZ and LIM ___domain 7 to inhibit adipogenesis and prevent obesity

Lu Fang
Changjie Liu
Lemin Zheng
ResearchOpen Access23 Aug 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-17
Occurrence and characterization of viruses infecting Amorphophallus in Yunnan, China

Jiahong Dong
Ting Zhu
Kuo Wu
ResearchOpen Access05 Jun 2024
Scientific Reports

Volume: 14, P: 1-15
The OX40-TRAF6 axis promotes CTLA-4 degradation to augment antitumor CD8⁺ T-cell immunity

Jizhang Yu
Jikai Cui
Jie Wu
Research07 Nov 2023
Cellular & Molecular Immunology

Volume: 20, P: 1445-1456
Author Correction: Longitudinal development of the human white matter structural connectome and its association with brain transcriptomic and cellular architecture

Guozheng Feng
Rui Chen
Ni Shu
Amendments and CorrectionsOpen Access11 Jan 2024
Communications Biology

Volume: 7, P: 1
p38α deficiency ameliorates psoriasis development by downregulating STAT3-mediated keratinocyte proliferation and cytokine production

p38α signaling promotes keratinocyte proliferation and psoriasis-related proinflammatory gene expression in psoriasis by activating STAT3, and further amplifies the IL-23/IL-17 pathogenic axis.

Tingting Zheng
Jiaqi Deng
Gonghua Huang
ResearchOpen Access15 Aug 2024
Communications Biology

Volume: 7, P: 1-13
Integrating transcriptome and microRNA analysis identifies genes and microRNAs for AHO-induced systemic acquired resistance in N. tabacum

Yongdui Chen
Jiahong Dong
Xuewen Wang
ResearchOpen Access02 Oct 2017
Scientific Reports

Volume: 7, P: 1-13
Multi-omics pan-cancer study of SPTBN2 and its value as a potential therapeutic target in pancreatic cancer

Hongliang Chang
Hong Chen
Deguang Sun
ResearchOpen Access29 Apr 2024
Scientific Reports

Volume: 14, P: 1-14
Multi-omics analyses of serum metabolome, gut microbiome and brain function reveal dysregulated microbiota-gut-brain axis in bipolar depression

Zhiming Li
Jianbo Lai
Shaohua Hu
Research20 Apr 2022
Molecular Psychiatry

Volume: 27, P: 4123-4135
IL-4 inhibits regulatory T cells differentiation by HDAC9-mediated epigenetic regulation

Jikai Cui
Heng Xu
Jie Wu
ResearchOpen Access18 May 2021
Cell Death & Disease

Volume: 12, P: 1-11
Effect of PM_2.5 pollution on perinatal mortality in China

Guangqin Li
Lingyu Li
Hongjun Zhu
ResearchOpen Access07 Apr 2021
Scientific Reports

Volume: 11, P: 1-12
Trends in the prevalence of overweight, obesity, and abdominal obesity among Chinese adults between 1993 and 2015

Shujing Ma
Bo Xi
Pascal Bovet
Research10 Oct 2020
International Journal of Obesity

Volume: 45, P: 427-437
Synthesis of thienoselenadiazole-containing conjugated copolymers and their application in polymer solar cells

A novel Se-containing heterocycle 4,6-Bis(4′-hexylthiophen-2′-yl)thieno[3,4-c][1,2,5]selenadiazole (DTTSe) was synthesized for the first time and used as a new acceptor unit for developing donor−acceptor-conjugated copolymers.

Xingxing Shen
Shan Chen
Liming Ding
Research28 Mar 2012
Polymer Journal

Volume: 44, P: 978-981
Longitudinal development of the human white matter structural connectome and its association with brain transcriptomic and cellular architecture

Joint connectomic and transcriptomic analyses of longitudinal dMRI data reveal the multiscale developmental pattern of the human white matter connectome from childhood to adolescence.

Guozheng Feng
Rui Chen
Ni Shu
ResearchOpen Access12 Dec 2023
Communications Biology

Volume: 6, P: 1-16
A ribosomal gene panel predicting a novel synthetic lethality in non-BRCAness tumors

Chao Zhang
Qiang Guo
Jin-San Zhang
ResearchOpen Access10 May 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-17
A multifunctional optoelectronic device based on 2D material with wide bandgap

A new type of luminescent nanocomposite based on 0D/2D vertical heterojunction is prepared, enabling the fabrication of a multifunctional optical device for blue light emission, light modulation and UV detection.

Hongwei Xu
Jingwei Liu
Baofu Ding
ResearchOpen Access22 Nov 2023
Light: Science & Applications

Volume: 12, P: 1-9
Aedes albopictus salivary adenosine deaminase is an immunomodulatory factor facilitating dengue virus replication

Xiaohui Mu
Zimin Lin
Jiahong Wu
ResearchOpen Access04 Oct 2023
Scientific Reports

Volume: 13, P: 1-14
Scalable synthesis of ultrastable lead halide perovskite-zeolite composites via a chemical vapor method in air

A facile chemical vapor method is developed for large-scale synthesis of CsPbX₃-ZSM-5 composites. Owing to the effective confinement and encapsulation of CsPbBr₃ QDs by ZSM-5, the composites possess excellent photophysical properties and ultrahigh stability. The prepared composites are applied in white light-emitting diodes (WLEDs) and multicolor-coded anti-counterfeiting inks. This technique provides the probability for commercial production of these perovskite composites with robust stability.

Tongyu Shi
Xi Chen
Xue-Feng Yu
ResearchOpen Access04 Nov 2022
NPG Asia Materials

Volume: 14, P: 1-12
Diterpenoid compounds from Wedelia trilobata induce resistance to Tomato spotted wilt virus via the JA signal pathway in tobacco plants

Lihua Zhao
Zhonghui Hu
Jiahong Dong
ResearchOpen Access26 Feb 2019
Scientific Reports

Volume: 9, P: 1-12
Developmental and reproductive toxicity of a recombinant protein subunit COVID-19 vaccine (ZF2001) in rats

Yisheng Song
Jinjin Shao
Lijiang Zhang
ResearchOpen Access24 May 2023
npj Vaccines

Volume: 8, P: 1-11
Correction: GNE myopathy in Chinese population: hotspot and novel mutations

Yang Chen
Jianying Xi
Jiahong Lu
Amendments and Corrections26 Dec 2018
Journal of Human Genetics

Volume: 64, P: 269
High-content imaging of human hepatic spheroids for researching the mechanism of duloxetine-induced hepatotoxicity

Juan Liu
Ruihong Li
Yunfang Wang
ResearchOpen Access01 Aug 2022
Cell Death & Disease

Volume: 13, P: 1-12
Deletion of TMEM268 inhibits growth of gastric cancer cells by downregulating the ITGB4 signaling pathway

Dubeiqi Hong
Xuan Zhang
Yingyu Chen
ResearchOpen Access25 Oct 2018
Cell Death & Differentiation

Volume: 26, P: 1453-1466
C/EBPβ promotes poly(ADP-ribose) polymerase inhibitor resistance by enhancing homologous recombination repair in high-grade serous ovarian cancer

Jiahong Tan
Xu Zheng
Qinglei Gao
ResearchOpen Access08 May 2021
Oncogene

Volume: 40, P: 3845-3858
TERT assists GDF11 to rejuvenate senescent VEGFR2⁺/CD133⁺ cells in elderly patients with myocardial infarction

This study shows how telomerase reverse transcriptase (TERT) assists growth differentiation factor 11 (GDF11) to rejuvenate senescent endothelial progenitor cells via the Smad2/3 and eNOS pathways. Therapeutically, it may be possible to exploit TERT mediated-GDF11 signaling to activate senescent stem cells in the myocardial ischemic microenvironment.

Lan Zhao
Shaoheng Zhang
Qunlin Gong
Research10 Jul 2019
Laboratory Investigation

Volume: 99, P: 1661-1688
A 14 nucleotide deletion mutation in the coding region of the PpBBX24 gene is associated with the red skin of “Zaosu Red” pear (Pyrus pyrifolia White Pear Group): a deletion in the PpBBX24 gene is associated with the red skin of pear

Chunqing Ou
Xiaoli Zhang
Zhihong Zhang
ResearchOpen Access01 Apr 2020
Horticulture Research

Volume: 7, P: 1-14

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