Aberrant coagulation and thrombosis are associated with severe SARS-CoV-2 infection. Here, the authors show that the E protein are associated with coagulation disorders in COVID-19 patients and could directly enhance platelet activation and thrombosis through a CD36/p38 MAPK/NF-kB signaling axis.
- Zihan Tang
- Yanyan Xu
- Tingting Liu
