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Cell Death & Disease (2)
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Showing 1–9 of 9 results

Advanced filters: Author: Jian-Hong Peng Clear advanced filters

GDF11 slows excitatory neuronal senescence and brain ageing by repressing p21

How excitatory neurons (EN) acquire senescence is unclear. Here, the authors show that GDF11 in ENs slows EN senescence, brain ageing, cognitive decline and maintains lifespan, revealing a mechanism underlying EN senescence and brain ageing.

Di-Xian Wang
Zhao-Jun Dong
Jing-Wei Zhao
ResearchOpen Access17 Nov 2023
Nature Communications

Volume: 14, P: 1-24
Mossy fiber expression of αSMA in human hippocampus and its relevance to brain evolution and neuronal development

Tian Tu
Xiao-Lu Cai
Qi-Lei Zhang
ResearchOpen Access06 May 2025
Scientific Reports

Volume: 15, P: 1-18
Pregnane X receptor alleviates sepsis-induced liver injury through activation of yes-associated protein in mice

Cheng-hua Wu
Shuang Hu
Hui-chang Bi
Research15 Apr 2025
Acta Pharmacologica Sinica

P: 1-13
CARD9^S12N facilitates the production of IL-5 by alveolar macrophages for the induction of type 2 immune responses

CARD9 serves as an adaptor for C-type lectin receptor signaling. Xin Lin and colleagues show that CARD9 inhibits RelB-mediated IL-5 expression. The CARD9^S12N mutant, prevalent in humans, cannot interact with RelB and promotes enhanced allergic responses to fungal pathogens.

Xia Xu
Jin-Fu Xu
Xin Lin
Research18 May 2018
Nature Immunology

Volume: 19, P: 547-560
Stage IV colon cancer patients without DENND2D expression benefit more from neoadjuvant chemotherapy

Wen-juan Ma
Yukun Chen
Rong-xin Zhang
ResearchOpen Access06 May 2022
Cell Death & Disease

Volume: 13, P: 1-12
TRAF3/STAT6 axis regulates macrophage polarization and tumor progression

Jian-Hong Shi
Li-Na Liu
Zhi-Yu Ni
Research21 Jul 2023
Cell Death & Differentiation

Volume: 30, P: 2005-2016
High-throughput proteomics profiling-derived signature associated with chemotherapy response and survival for stage II/III colorectal cancer

Shu-Biao Ye
Yi-Kan Cheng
Ping Lan
ResearchOpen Access31 May 2023
npj Precision Oncology

Volume: 7, P: 1-12
TRK-fused gene (TFG) regulates ULK1 stability via TRAF3-mediated ubiquitination and protects macrophages from LPS-induced pyroptosis

Jian-Hong Shi
Chen Ling
Zhi-Yu Ni
ResearchOpen Access28 Jan 2022
Cell Death & Disease

Volume: 13, P: 1-11
Association of mismatch repair status with survival and response to neoadjuvant chemo(radio)therapy in rectal cancer

Shu-Biao Ye
Yi-Kan Cheng
Ping Lan
ResearchOpen Access07 Sept 2020
npj Precision Oncology

Volume: 4, P: 1-9