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Generation of mature oocytes requires tight regulation of a discontinuous meiotic cell cycle. Here they show that the acetyltransferase Nat10 mediates modification of RNAs targeted for degradation and find that this process is essential for female oocyte meiosis and maturation.

The authors undertake a global-scale, long-term analysis of trends in post-fire biomass recovery, examining the influence of fire severity and climatic drivers before and after 2010. They find that since 2001 forest recovery has been increasingly sensitive to fire severity.

Graphene has demonstrated the ability to modulate terahertz (THz) waves by optical or electrical excitation, but modulation depths have been low. Here, Li et al. demonstrate enhanced modulation and polarity-dependent THz attenuation using external voltage bias and photoexcitation on a graphene–silicon film.

The stability and delivery of biopesticides limits application. Here, azadirachtin is co-assembled with plant secondary metabolites for efficient drug delivery, demonstrating pest management, the activation of plant defensive capacity, while increasing the production yield of crops.

Urinary proteomics offers sensitive, non-invasive biomarkers, but cross-platform LC-MS data comparability requires investigation. Here, the authors evaluate 20 LC-MS platforms, developing MSCohort, a QC system with 81 metrics, and a unified SOP, paving the way for precision medicine research.

A transcontinental drainage system transported sediments from the North China Craton into the eastern Paleo-Tethys Ocean in the Middle Triassic, as shown by a multi-proxy provenance and paleogeographic study from MiddleTriassic sediments from the North China Craton, Qinling, and Songpan-Ganzi regions.

Optimized agricultural managements enhance wheat yields by 7−14% in China under future climate scenarios without expanding current cultivation areas, according to a 3-year field experiment at 22 sites and crop model simulations.

The generation of nitrogen-centred radicals and their subsequent reaction with control of stereoselectivity is a difficult task in synthetic chemistry. Now, the photoenzymatic production of nitrogen-centred radicals and their use in challenging enantioselective intermolecular radical hydroaminations is reported.

ATP13A2 is a lysosomal polyamine transporter, mutated in several diseases including juvenile-onset Parkinson’s disease. Here, the authors report structures of human ATP13A2 in six distinct intermediate states, illustrating most of its conformational cycle.

Chondrocyte senescence is known to play a role in the occurrence and progression of osteoarthritis. Here, the authors demonstrate that 10-hydroxy-2-decenoic acid (10-HDA), a small molecule derived from the food nutrient royal jelly, can prevent osteoarthritis by delaying chondrocyte senescence through targeting aspartyl β-hydroxylase.

The origin of energetic charged particles in universe remains an unresolved issue, while one of the promising mechanism contributions is stochastic acceleration. Here the authors demonstrate electron stochastic acceleration of kinetic turbulence in a lab setting.

The incidence of young-onset sporadic colorectal cancer (yCRC) is rapidly rising and frequently associated with an aggressive disease. Here the authors show that gut microbial diversity is increased in patients with yCRC compared to old-onset CRC and that fecal microbial markers could be used to detect individuals with yCRC.

In vivo decorporation of U(VI) from bones is an unsolved challenge because of the formation of stable uranium phosphate complexes. Here, the authors develop a hydroxypyridonone-based ligand with strong uranium complexation and low cytotoxicity. They find this ligand effectively removes uranium from kidney and bones in mice, and is suitable for oral administration.

Subgrade settlement is a serious distress which poses a huge threat to the service life and operation safety of roads. Here, authors propose the application of ground-penetrating radar as technical solution for the quality evaluation of ground improvement in soft soil subgrade reinforcement engineering.

Kenneth Kinzler and colleagues report exome sequencing of ten hepatocellular carcinoma tumors and matched normal tissue. They identify inactivating mutations in the chromatin remodeling gene ARID2 in a total of 9 out of 139 HCC tumors.

The role of social resilience in mitigating hunger related to climate change is explored in North Korea, South Korea and China, regions with similar climatic conditions but varying levels of economic development.

ROS is an important defense means against pathogens for host. Here the authors show that PsAF5 functions as a mitophagy adapter and regulates mitochondrial homeostasis in Phytophthora sojae under ROS stress, which is crucial for its infection.

Transparent YAG crystals are ubiquitous in phosphors, scintillators and lasers, but are complex and costly to make. Here, the authors use a one-step pressureless crystallization of bulk glass to make a transparent biphasic YAG nanoceramic that can be doped for optical applications.

Reverse O spillover has opened new opportunities in improving the catalytic activity and selectivity in various reactions. Herein Sn is doped into TiO2 to activate low-temperature (<100 °C) reverse oxygen spillover in Pt/TiO2 catalyst, leading to enhanced CO oxidation activity.

Understanding major sources of uncertainty in yield change facilitates adaptation strategies for cropping systems. Using eight crop models, 32 global climate models and two climate downscaling methods, it is shown that their relative contribution to uncertainty in climate–crop modelling depends on ___location.

De novo genome assemblies of 12 species from Aurantioideae and pangenome analyses provide insights into the origin and evolution of the orange subfamily and the genetic basis of flavor in citrus fruits.

Dodders (Cuscuta spp., Convolvulaceae) are root- and leafless parasitic plants. Here, the authors sequence the genome of Cuscuta australis and find remarkable gene loss associated with parasitic lifestyle and large changes in body plan.

Magnetic reconnection governs many astrophysical phenomena, but its details are poorly understood. The extreme magnetic fields generated by the interaction of a high-intensity laser with a plasma enables the study of magnetic reconnection processes similar to those that occur in solar flares.

Rice false smut, caused by the pathogenic ascomycete fungus Ustilaginoidea virens (Cooke) Takah, has a significant economic impact on crop production. Here, Zhang et al. report the draft genome sequence of U. virensand provide insight into the evolution of genes involved in pathogenicity and adaptation to a biotrophic and floret-infecting lifestyle.

Single-atom metal catalysts offer maximized material efficiency, but there is large room to improve the intrinsic activity per metal atom for many reactions. Here, the authors demonstrate that the solution for CO oxidation is to tackle the issue of lacking neighboring Pt atoms in the single-atom Pt1/CeO2 system.

Expansion of human hematopoietic stem cells present in cord blood or bone marrow can be achieved by cell culture in a hydrogel, potentially facilitating clinical applications of hematopoietic cell transplantation.

Laboratory experiments reveal the underlying mechanism of turbulent reconnection, including electron acceleration. These findings are directly relevant for studies of flares in the solar corona.

The independently evolved extreme holoparasites Balanophora and Sapria display convergent characteristics of genome modifications, including gene loss in particular pathways, reduction of multigene families and relaxed selection pressures.

Miniature inverted-repeat transposable elements (MITEs) are common components of eukaryotic genomes. Here the authors show that a stowaway-like MITE in the 3′-untranslated region of the riceGhd2gene can suppress translation in a DCL3a-dependent manner representing a novel role for transposons in translation.

The molecular basis for the unique taste and aroma of tea cultivars is largely unknown, but is critical for breeding new cultivars. Here the authors use transcriptomics and metabolomics to study the relationship among phylogenetic groups and specialized metabolites from 136 tea accessions in China.