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Showing 101–150 of 211 results

Advanced filters: Author: Jiaxing Chen Clear advanced filters

The role of immune cells and immune related genes in the tumor microenvironment of papillary thyroid cancer and their significance for immunotherapy

Xumei Li
Jie Jian
Yanlin Chen
ResearchOpen Access05 Aug 2024
Scientific Reports

Volume: 14, P: 1-14
De novo analysis of bulk RNA-seq data at spatially resolved single-cell resolution

Current methods to reanalyze bulk RNA-seq at spatially resolved single-cell resolution have limitations. Here, the authors develop Bulk2Space, a spatial deconvolution algorithm using single-cell and spatial transcriptomics as references, providing new insights into spatial heterogeneity within bulk tissue.

Jie Liao
Jingyang Qian
Xiaohui Fan
ResearchOpen Access30 Oct 2022
Nature Communications

Volume: 13, P: 1-19
A novel GAN-based regression model for predicting frying oil deterioration

Kai Ye
Zhenyu Wang
Xiaohui Cui
ResearchOpen Access21 Jun 2022
Scientific Reports

Volume: 12, P: 1-8
Optimizing rabies mRNA vaccine efficacy via RABV-G structural ___domain screening and heterologous prime-boost immunization

Dongdong Li
Xuan Wang
Yan Chen
ResearchOpen Access02 Mar 2025
npj Vaccines

Volume: 10, P: 1-13
Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice

Here the authors show that the Koolen-de Vries syndrome associated gene KANSL1 modulates autophagosome-lysosome fusion via transcriptional regulation of autophagosomal gene Syntaxin17, and that 13-cis retinoic acid can reverses mitophagic defects and neurobehavioural abnormalities of mice lacking Kansl1.

Ting Li
Dingyi Lu
Xin Pan
ResearchOpen Access17 Feb 2022
Nature Communications

Volume: 13, P: 1-16
Inferring transcription factor regulatory networks from single-cell ATAC-seq data based on graph neural networks

Transcription factor regulatory networks underlie major features of cellular identity and complex function such as pluripotency, development and differentiation. Li and colleagues develop a graph neural network to predict transcription factor regulatory networks based on single-cell ATAC-seq data.

Hao Li
Yu Sun
Xiaochen Bo
Research11 Apr 2022
Nature Machine Intelligence

Volume: 4, P: 389-400
Hybrid magnetoresistance in Pt-based multilayers: Effect originated from strong interfacial spin-orbit coupling

Kangkang Meng
Jiaxing Xiao
Yong Jiang
ResearchOpen Access04 Feb 2016
Scientific Reports

Volume: 6, P: 1-9
Formation of H₃⁺ from ethane dication induced by electron impact

H₃⁺has great astronomical significance, but its formation mechanisms are not fully understood. Here a combined experimental and theoretical study of H₃⁺ formation dynamics from ethane dications shows that roaming occurs at a much longer timescale than the transition state, and is accompanied by nuclear motion of larger amplitudes.

Yu Zhang
Baihui Ren
Baoren Wei
ResearchOpen Access09 Nov 2020
Communications Chemistry

Volume: 3, P: 1-6
A pan-immune panorama of bacterial pneumonia revealed by a large-scale single-cell transcriptome atlas

Kun Xiao
Yan Cao
Yi Wang
ResearchOpen Access06 Jan 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-17
Synthesis and characterization of polyethylene glycol-phenol-formaldehyde based polyurethane composite

Juan Liu
RiQing Chen
FuXiang Chu
ResearchOpen Access20 Dec 2019
Scientific Reports

Volume: 9, P: 1-9
Mirror-image polymerase chain reaction

Wenjun Jiang
Baochang Zhang
Ting F Zhu
ResearchOpen Access17 Oct 2017
Cell Discovery

Volume: 3, P: 1-7
Reconstruction of the cell pseudo-space from single-cell RNA sequencing data with scSpace

Methods to reanalyze scRNA-seq data in a spatial perspective are vital but lacking. Here, the authors develop scSpace, an integrative method that uses ST data as spatial reference to reconstruct the pseudo-space of scRNA-seq data and identify spatially variable cell subpopulations, providing insights into spatial heterogeneity from scRNA-seq data.

Jingyang Qian
Jie Liao
Xiaohui Fan
ResearchOpen Access29 Apr 2023
Nature Communications

Volume: 14, P: 1-18
Four-octyl itaconate improves osteoarthritis by enhancing autophagy in chondrocytes via PI3K/AKT/mTOR signalling pathway inhibition

4-octyl itaconate (OI) attenuates chondrocyte apoptosis and ameliorates cartilage degradation and defection of autophagy induced by IL-1 β via the PI3K/AKT/mTOR pathway. OI improved the autophagy and reduced the inflammation of rat models of osteoarthritis.

Xuekang Pan
Huajian Shan
Xiaozhong Zhou
ResearchOpen Access29 Jun 2022
Communications Biology

Volume: 5, P: 1-10
High expression of IMPDH2 is associated with aggressive features and poor prognosis of primary nasopharyngeal carcinoma

Yi Xu
Zhousan Zheng
Jiaxing Zhang
ResearchOpen Access07 Apr 2017
Scientific Reports

Volume: 7, P: 1-10
Total chemical synthesis of a thermostable enzyme capable of polymerase chain reaction

Weiliang Xu
Wenjun Jiang
Ting F Zhu
ResearchOpen Access28 Feb 2017
Cell Discovery

Volume: 3, P: 1-10
Author Correction: Kansl1 haploinsufficiency impairs autophagosome-lysosome fusion and links autophagic dysfunction with Koolen-de Vries syndrome in mice

Ting Li
Dingyi Lu
Xin Pan
Amendments and CorrectionsOpen Access17 Mar 2022
Nature Communications

Volume: 13, P: 1
Screening and identification of five serum proteins as novel potential biomarkers for cured pulmonary tuberculosis

Chong Wang
Li-Liang Wei
Ji-Cheng Li
ResearchOpen Access26 Oct 2015
Scientific Reports

Volume: 5, P: 1-11
A preliminary exploration of establishing a mice model of hypoxic training

Minglu Li
Zhijie Chen
Jiaxing Zhang
ResearchOpen Access04 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
Shipborne oceanic high-spectral-resolution lidar for accurate estimation of seawater depth-resolved optical properties

Shipborne oceanic high-spectral-resolution lidar for accurate estimation of seawater depth-resolved optical properties

Yudi Zhou
Yang Chen
Dong Liu
ResearchOpen Access02 Sept 2022
Light: Science & Applications

Volume: 11, P: 1-13
JOSD2 inhibits angiotensin II-induced vascular remodeling by deubiquitinating and stabilizing SMAD7

Si-rui Shen
Zhu-qi Huang
Guang Liang
Research20 Jan 2025
Acta Pharmacologica Sinica

Volume: 46, P: 1275-1288
Topic modeling and content analysis of people’s anxiety-related concerns raised on a computer-mediated health platform

Yi Liu
Yi Shan
Yong Shen
ResearchOpen Access11 Nov 2024
Scientific Reports

Volume: 14, P: 1-15
Empagliflozin in children with glycogen storage disease-associated inflammatory bowel disease: a prospective, single-arm, open-label clinical trial

Zhiling Li
Xiaoyan Zhang
Min Yang
ResearchOpen Access15 Apr 2024
Scientific Reports

Volume: 14, P: 1-10
Anisotropy-free arrayed waveguide gratings on X-cut thin film lithium niobate platform of in-plane anisotropy

A universal strategy to realize anisotropy-free dispersive components, such as arrayed waveguide gratings, on a uniaxial in-plane anisotropic thin-film lithium niobate platform is introduced for the first time.

Junjie Yi
Changjian Guo
Liu Liu
ResearchOpen Access29 Jun 2024
Light: Science & Applications

Volume: 13, P: 1-11
Physical twinning for joint encoding-decoding optimization in computational optics: a review

Liheng Bian
Xinrui Zhan
Jun Zhang
ReviewsOpen Access15 Apr 2025
Light: Science & Applications

Volume: 14, P: 1-20
IGF2BP3 enhances lipid metabolism in cervical cancer by upregulating the expression of SCD

Chenying Han
Chenchen Hu
Shuya Yang
ResearchOpen Access14 Feb 2024
Cell Death & Disease

Volume: 15, P: 1-11
Ventilatory pressure parameters impact the association between acute gastrointestinal injury and all-cause mortality in mechanically ventilated patients

Shao Ziqiang
Li Jiale
Hu Bangchuan
ResearchOpen Access05 Sept 2024
Scientific Reports

Volume: 14, P: 1-11
Genetically encoded fluorescent sensors reveal dynamic regulation of NADPH metabolism

Genetically encoded iNap sensors allow imaging of NADPH with high spatiotemporal resolution in living systems. The iNaps cover physiologically relevant NADPH concentrations and are demonstrated in mammalian cells and live zebrafish.

Rongkun Tao
Yuzheng Zhao
Yi Yang
Research05 Jun 2017
Nature Methods

Volume: 14, P: 720-728
A coordinated adaptive multiscale enhanced spatio-temporal fusion network for multi-lead electrocardiogram arrhythmia detection

Zicong Yang
Aitong Jin
Yan Liu
ResearchOpen Access06 Sept 2024
Scientific Reports

Volume: 14, P: 1-19
Prosapogenin A induces GSDME-dependent pyroptosis of anaplastic thyroid cancer through vacuolar ATPase activation-mediated lysosomal over-acidification

Yunye Liu
Yawen Guo
Guowan Zheng
ResearchOpen Access13 Aug 2024
Cell Death & Disease

Volume: 15, P: 1-15
Political connection and credit risk of real estate enterprises: evidence from stock market

Rongda Chen
Jingjing Yu
Shuonan Zhang
ResearchOpen Access26 Jan 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-12
Autophagy activation prevents sevoflurane-induced neurotoxicity in H4 human neuroglioma cells

You-fa Zhou
Qing-xia Wang
Gang Chen
Research04 Apr 2016
Acta Pharmacologica Sinica

Volume: 37, P: 580-588
Evidence for temporal relationship between the late Mesozoic multistage Qianlishan granite complex and the Shizhuyuan W–Sn–Mo–Bi deposit, SE China

Yuzhong Liao
Bo Zhao
Feng Liu
ResearchOpen Access12 Mar 2021
Scientific Reports

Volume: 11, P: 1-23
The OsSPL16-GW7 regulatory module determines grain shape and simultaneously improves rice yield and grain quality

Xiangdong Fu and colleagues show that variation in GW7 influences rice grain shape and yield. They further show that GW7 expression is directly regulated by OsSPL16, a transcription factor encoded by the grain-width locus GW8.

Shaokui Wang
Shan Li
Xiangdong Fu
Research06 Jul 2015
Nature Genetics

Volume: 47, P: 949-954
Depressive symptoms mediate the longitudinal relationships between sleep quality and cognitive functions among older adults with mild cognitive impairment: A cross-lagged modeling analysis

Jiayu Wang
Shulin Chen
Jiang Xue
ResearchOpen Access11 Sept 2024
Scientific Reports

Volume: 14, P: 1-9
Design and implementation of virtual fitting system based on gesture recognition and clothing transfer algorithm

Ying Wu
Hongbing Liu
Fangjian Yuan
ResearchOpen Access01 Nov 2022
Scientific Reports

Volume: 12, P: 1-13
A cross-sectional study on the relationship between visceral adiposity index and periodontitis in different age groups

Qinghua Yang
Xuming Wang
Xuanming Wang
ResearchOpen Access10 Apr 2023
Scientific Reports

Volume: 13, P: 1-8
The southward shift of hurricane genesis over the northern Atlantic Ocean

Xi Cao
Renguang Wu
Xiao Xiao
ResearchOpen Access30 Jan 2025
npj Climate and Atmospheric Science

Volume: 8, P: 1-10
Pathophysiological role of ion channels and transporters in hepatocellular carcinoma

Li Zhang
Hong Gu
Biguang Tuo
ReviewsOpen Access24 Jul 2024
Cancer Gene Therapy

Volume: 31, P: 1611-1618
Interprovincial food trade aggravates China’s land scarcity

Jianjian He
Siqi Wang
Kai Fang
ResearchOpen Access08 Jan 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-14
Research on nash game model for user side shared energy storage pricing

Weijie Qian
Chao Chen
Wei Zhang
ResearchOpen Access26 Sept 2023
Scientific Reports

Volume: 13, P: 1-9
In-situ tool wear condition monitoring during the end milling process based on dynamic mode and abnormal evaluation

Min Chen
Jianwei Mao
Weifang Sun
ResearchOpen Access05 Jun 2024
Scientific Reports

Volume: 14, P: 1-14
Generalization of cut-in pre-crash scenarios for autonomous vehicles based on accident data

Pingfei Li
Xinyu Zhu
Chang Xu
ResearchOpen Access26 Jul 2024
Scientific Reports

Volume: 14, P: 1-15
Hepatocellular carcinoma-specific epigenetic checkpoints bidirectionally regulate the antitumor immunity of CD4 + T cells

Shuai Wang
Lijun Meng
Xiao Xu
Research19 Sept 2024
Cellular & Molecular Immunology

Volume: 21, P: 1296-1308
Author Correction: Synthesis and characterization of polyethylene glycol-phenol-formaldehyde based polyurethane composite

Juan Liu
RiQing Chen
FuXiang Chu
Amendments and CorrectionsOpen Access10 Mar 2020
Scientific Reports

Volume: 10, P: 1
Relationship between oxide identity and electrocatalytic activity of platinum for ethanol electrooxidation in perchlorate acidic solution

Interfacial water and its dissociated species play key roles in aqueous electrocatalysis. Here, the authors study the ethanol electrooxidation on platinum electrodes at potentials up to 1.5 V vs. RHE and find that the oxygen species stemming from water, PtOH_ads, and α-PtO₂ act as catalytic centers.

Xinyu You
Jiaxing Han
Qingyu Gao
ResearchOpen Access29 May 2023
Communications Chemistry

Volume: 6, P: 1-9
Clinical trial and performance evaluation of the Wantai HBsAg (CMIA) diagnostic kit for screening blood donors in China

Jianfeng Chen
Fengtian Wang
Chen Xiao
ResearchOpen Access02 Feb 2024
Scientific Reports

Volume: 14, P: 1-13
RARRES2 is involved in the “lock-and-key” interactions between osteosarcoma stem cells and tumor-associated macrophages

Jingjin Ma
Zhiyu Chen
Zhengxue Quan
ResearchOpen Access27 Jan 2024
Scientific Reports

Volume: 14, P: 1-19
Pituitary-derived small extracellular vesicles promote liver repair by its cargo miR-143-3p

Jia-Li Xiong
Yu-Xuan Wang
Yong-Liang Zhang
ResearchOpen Access18 Jul 2024
Scientific Reports

Volume: 14, P: 1-15
Cutaneous adverse events in patients treated with PD-1/PD-L1 checkpoint inhibitors and their association with survival: a systematic review and meta-analysis

Fangmin Zhao
Junjing Zhu
Qijin Shu
ResearchOpen Access21 Nov 2022
Scientific Reports

Volume: 12, P: 1-12
A novel SNP in promoter region of RP11-3N2.1 is associated with reduced risk of colorectal cancer

Ding Ye
Yunqing Hu
Kun Chen
Research05 Oct 2017
Journal of Human Genetics

Volume: 63, P: 47-54

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