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The mechanism of HBsAg antigen presentation to T cells during liver HBV infection is incompletely understood. Here, the authors show that in mice, intrahepatic type I dendritic cells acquire HBsAg by MHC-I complexes through cross-dressing for CD8⁺ T cell priming, whereas CD4⁺ T cell responses rely on MHC-II-dependent antigen presentation by B cells in secondary lymphoid tissues.

Li et al. characterized the gene GRAVITROPISM LOSS 1 (OsGLS1) in rice, which regulates root system architecture (RSA) to enhance nutrient uptake and yield. OsGLS1 promotes the degradation of OsPIN2, influencing auxin transport and root growth patterns.

The complication of water adsorption on surfaces goes well beyond a simple hexagonal bilayer model predicted by the ice rule. Chen et al.observe an extended cyclical pattern of water tetramers on an insulator surface, which is attributable to the formation of periodic Bjerrum defects at high density.

The mechanisms of the natural control of hepatitis B virus infection remain obscured. Here, the authors reveal that matrix stiffness influences HBV replication via YAP-mediated mechanosignaling, uncovering a novel non-cytolytic mechanism for clearing viral infections in the liver.

Resolving the internal structure of water molecules adsorbed on solid surfaces is challenging. Submolecular-resolution imaging of individual water monomers and tetramers on NaCl(001) films supported by a Au(111) substrate is now reported. The molecular orbitals of adsorbed water were directly visualized, which lead to the discrimination between the orientation of the monomers and the tetramers H-bond directionality.

Cardiac ischemia–reperfusion (I/R) injury represents a key threat to human health. This study reveals that the long noncoding RNA lncRNA-CIRBIL is protective against I/R injury by inhibiting the nuclear translocation of Bclaf1.

Health-oriented emissions reduction in China focusing on the iron and steel industry can reduce costs by 1.56 billion dollars while lowering the population-weighted toxic potency-adjusted exposure risk.

Carbon materials are promising for perovskite solar cells but suffer from poor interfacial energy level alignment. Now, Zhang et al. show that Ti atomically dispersed in reduced graphene reduces energy losses improving device performance.

Microwell-seq is used to generate single-cell, whole-body expression landscapes of zebrafish, Drosophila and earthworm. A deep-learning model, Nvwa, predicts gene expression from DNA sequence and identifies regulatory programs shared across eight species.

Ion migration has a detrimental effect on the performance and stability of halide perovskite optoelectronics. Here, the authors incorporated a small dosage of high-valence neodymium cation to suppress this, with a minimal impact on the lattice microstrain.

Acute-on-chronic liver failure (ACLF) is characterized by rapid deterioration of liver function in patients with chronic liver disease. Here, the authors show that BTLA expression in CD4⁺ T cells is associated with disease severity and inflammation in hepatitis B virus-related ACLF.

Large numbers of leaves fall off trees each autumn. Here, the authors turn dead leaves into an active material which acts as bioplastic and shows high performance in solar water evaporation, photocatalytic H₂ production and antibiotic degradation.

The authors show a reductive interlayer structure that renders semi-transparent solar cells with a favourable combination of high efficiency and improved operational stability. When integrated in greenhouses, plant growth is comparable to that in the traditional glass-roof mode.

The wild rice species can be used as germplasm resources for this crop’s genetic improvement. Here Chen and colleagues report the de novo sequencing of the O. brachyanthagenome, and identify the origin of genome size variation, the role of gene movement and its implications on heterochromatin evolution in the rice genome.

At high pressure, water forms superionic ice with an oxygen lattice and melted liquid hydrogens, which could exist on ice-rich planets. Here, Sun et al. predict a new phase of superionic ice where the hydrogens preferentially diffuse in two-dimensions within oxygen superlattice with the P2₁/c symmetry.

High performance and multifunctional tandem QLED is achieved by face-to-face integrating a top-emitting QLED with a transparent QLED, which exhibits a record-breaking EQE of 60.7% and can operate in series, parallel, and color-tunable modes.

The discovery of thermodynamically stable thermoelectric materials for power generation has relied on empirical methods that were not effective. Here, the authors apply the inverse design approach to identify and experimentally realize TaFeSb-based half Heuslers with high thermoelectric performance.

Wide adoption of electric vehicles can contribute to mitigate climate change and air pollution. Here the authors develop various fleet electrification scenarios in China to evaluate the associated air quality and health impacts to inform sound policies.

A comprehensive map of genomic variation in melon derived from resequencing of 1,175 accessions sheds light on the population structure and domestication history of melon and agronomic traits for melon breeding.

Cobalt oxide nanoparticles can carry out overall water splitting with a solar-to-hydrogen efficiency of around 5%.

Strontium titanate can act as a transparent protection layer for silicon photocathodes, preventing corrosion without compromising photocatalytic redox activity.

The genome of the biofuel crop switchgrass (Panicum virgatum) reveals climate–gene–biomass associations that underlie adaptation in nature and will facilitate improvements of the yield of this crop for bioenergy production.

A 3D-printing technique has been developed to create high-quality pure silica nanostructures with sub-200 nm resolution and the flexible capability of rare-earth element doping. It shows excellent application potential in three-dimensional micro- and nanophotonics.

Contact tracing using mobile phones has been a strategy used by many countries to limit the spread of COVID-19. Here, the authors use ___location-related phone data from Wuhan to construct a temporal contact graph and demonstrate a strong correlation between contacts level and epidemic size, thus justifying the effectiveness of the approach.

Researchers from Hawaii and an international consortium have produced a draft genome assembly for 'SunUp', the first commercial virus-resistant transgenic fruit tree. Comparison of this plant genome to those of Arabidopsis and others sheds light on evolution of characteristics such as biosynthesis, starch deposition, control of photosynthesis and pathways for creating volatile compounds.