Nature Search

Production of Transgenic Cloned Miniature Pigs with Membrane-bound Human Fas Ligand (FasL) by Somatic Cell Nuclear Transfer

Jae Goo Seol
Soo Hyun Kim
Jae Young Heo
ResearchOpen Access15 Jun 2010
Nature Precedings

P: 1
Genome sequence of the hot pepper provides insights into the evolution of pungency in Capsicum species

Doil Choi and colleagues report the genome sequence of the hot pepper, Capsicum annuum, as well as the resequencing of two cultivated peppers and a wild species, Capsicum chinense. Comparative genomic analysis across Solanaceae provides insights into genome expansion, pungency, ripening and disease resistance in hot peppers.

Seungill Kim
Minkyu Park
Doil Choi
ResearchOpen Access19 Jan 2014
Nature Genetics

Volume: 46, P: 270-278
Genome-wide functional analysis of phosphatases in the pathogenic fungus Cryptococcus neoformans

Phosphatases are key components in cellular signalling networks. Here, the authors present a systematic functional analysis of phosphatases of the fungal pathogen Cryptococcus neoformans, revealing roles in virulence, stress responses, O-mannosylation, retromer function and other processes.

Jae-Hyung Jin
Kyung-Tae Lee
Yong-Sun Bahn
ResearchOpen Access24 Aug 2020
Nature Communications

Volume: 11, P: 1-17
The human hepatitis B virus transactivator X gene product regulates Sp1 mediated transcription of an insulin-like growth factor II promoter 4

Young Ik Lee
Sook Lee
Ha Ryung Poo
Research26 May 1998
Oncogene

Volume: 16, P: 2367-2380
PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development

The genetic link between placenta function and congenital heart defects has been established, though the cellular mechanisms underlying this connection is less clear. Here they show that PIBF1 regulates syncytiotrophoblast fusion and that loss of PIBF1 also negatively impacts heart development, providing a potential link between the development of these two organs.

Jong Geol Lee
Jung-Min Yon
In-Jeoung Baek
ResearchOpen Access19 Feb 2024
Nature Communications

Volume: 15, P: 1-19
Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype

The prognosis and treatment of gastric cancer is complicated by heterogeneity. Here, the authors reveal two molecular subtypes, the mesenchymal subtype associated with poor survival and chemoresistance, and the epithelial phenotype associated with better survival and sensitivity to chemotherapy.

Sang Cheul Oh
Bo Hwa Sohn
Ju-Seog Lee
ResearchOpen Access03 May 2018
Nature Communications

Volume: 9, P: 1-14
Socially transmitted placebo effects

Here we demonstrate that patients’ pain experiences are directly modulated by providers’ expectations of treatment outcomes in a simulated clinical interaction, providing evidence of a socially transmitted placebo effect.

Pin-Hao A. Chen
Jin Hyun Cheong
Luke J. Chang
Research21 Oct 2019
Nature Human Behaviour

Volume: 3, P: 1295-1305
Deep Gaussian process with uncertainty estimation for microsatellite instability and immunotherapy response prediction from histology

Sunho Park
Morgan F. Pettigrew
Tae Hyun Hwang
ResearchOpen Access19 May 2025
npj Digital Medicine

Volume: 8, P: 1-15
Multiple sgRNAs with overlapping sequences enhance CRISPR/Cas9-mediated knock-in efficiency

Da Eun Jang
Jae Young Lee
Su Cheong Yeom
ResearchOpen Access06 Apr 2018
Experimental & Molecular Medicine

Volume: 50, P: 1-9
Genotype–phenotype correlation of X-linked Alport syndrome observed in both genders: a multicenter study in South Korea

Ji Hyun Kim
Seon Hee Lim
Hae Il Cheong
ResearchOpen Access26 Apr 2023
Scientific Reports

Volume: 13, P: 1-10
Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis. Here, the authors study the roles played by 129 putative kinases in the growth and virulence of C. neoformans, identifying potential targets for development of anticryptococcal drugs.

Kyung-Tae Lee
Yee-Seul So
Yong-Sun Bahn
ResearchOpen Access28 Sept 2016
Nature Communications

Volume: 7, P: 1-16
Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids

Brain organoids derived from human pluripotent stem cells can model human brain development and disease, though current culture systems fail to ensure reliable production of high-quality organoids. Here the authors combine human brain extracellular matrix and culture in a microfluidic device to promote structural and functional maturation of human brain organoids.

Ann-Na Cho
Yoonhee Jin
Seung-Woo Cho
ResearchOpen Access05 Aug 2021
Nature Communications

Volume: 12, P: 1-23
Development and validation of a prognostic and predictive 32-gene signature for gastric cancer

The ability to predict the survival and response to treatment of cancer patients may improve patient care. Here, the authors generate a 32 gene signature that can predict the survival and response to treatment in gastric cancer patients.

Jae-Ho Cheong
Sam C. Wang
Tae Hyun Hwang
ResearchOpen Access09 Feb 2022
Nature Communications

Volume: 13, P: 1-9
A multifunctional core–shell nanoparticle for dendritic cell-based cancer immunotherapy

Iron oxide and zinc oxide core–shell nanoparticles can deliver antigens into dendritic cells and also act as an imaging agent for cancer immunotherapy.

Nam-Hyuk Cho
Taek-Chin Cheong
Seung-Yong Seong
Research11 Sept 2011
Nature Nanotechnology

Volume: 6, P: 675-682
Three-dimensional brain-like microenvironments facilitate the direct reprogramming of fibroblasts into therapeutic neurons

Hydrogels made from decellularized human brain tissue facilitate the direct conversion of primary mouse embryonic fibroblasts into induced neuronal cells that lead to therapeutic outcomes after transplantation in an animal model of ischaemic stroke.

Yoonhee Jin
Jung Seung Lee
Seung-Woo Cho
Research11 Jul 2018
Nature Biomedical Engineering

Volume: 2, P: 522-539
Atomic-scale combination of germanium-zinc nanofibers for structural and electrochemical evolution

Alloy anode materials are receiving renewed interest. Here the authors show the design of Ge-Zn nanofibers for lithium ion batteries. Featured by a homogeneous composition at the atomic level and other favorable structural attributes, the materials allow for impressive electrochemical performance.

Gyujin Song
Jun Young Cheong
Soojin Park
ResearchOpen Access30 May 2019
Nature Communications

Volume: 10, P: 1-11
Cross-species oncogenic signatures of breast cancer in canine mammary tumors

Comparison of spontaneous canine cancers and human cancers may illuminate future therapeutic avenues. Here, genomic analyses of these tumors highlights a convergence on PI3K-Akt oncogenic pathways.

Tae-Min Kim
In Seok Yang
Sangwoo Kim
ResearchOpen Access17 Jul 2020
Nature Communications

Volume: 11, P: 1-13
Interobserver variability in clinical target volume delineation in anal squamous cell carcinoma

Kyung Su Kim
Kwang-Ho Cheong
Hae Jin Park
ResearchOpen Access02 Feb 2021
Scientific Reports

Volume: 11, P: 1-7
Coherent many-body exciton in van der Waals antiferromagnet NiPS₃

A spin–orbit-entangled exciton state in the van der Waals material NiPS₃ is observed, and found to arise from many-body states of a Zhang–Rice singlet.

Soonmin Kang
Kangwon Kim
Je-Geun Park
Research20 Jul 2020
Nature

Volume: 583, P: 785-789
Enhanced heat transfer is dependent on thickness of graphene films: the heat dissipation during boiling

Ho Seon Ahn
Jin Man Kim
Moo Hwan Kim
ResearchOpen Access03 Sept 2014
Scientific Reports

Volume: 4, P: 1-6
SLC5A3 depletion promotes apoptosis by inducing mitochondrial dysfunction and mitophagy in gemcitabine-resistant pancreatic cancer cells

Minsoo Kim
Woosol Chris Hong
Joon Seong Park
ResearchOpen Access07 Mar 2025
Cell Death & Disease

Volume: 16, P: 1-11
TPX2 prompts mitotic survival via the induction of BCL2L1 through YAP1 protein stabilization in human embryonic stem cells

Yun-Jeong Kim
Young-Hyun Go
Hyuk-Jin Cha
ResearchOpen Access04 Jan 2023
Experimental & Molecular Medicine

Volume: 55, P: 32-42
Gene-environment interaction counterbalances social impairment in mouse models of autism

Ji-Woon Kim
Kwanghoon Park
Chan Young Shin
ResearchOpen Access07 Aug 2019
Scientific Reports

Volume: 9, P: 1-10
Prognostic role of copeptin after stroke: A systematic review and meta-analysis of observational studies

Kyu-Sun Choi
Hyun Jung Kim
Seon-Heui Lee
ResearchOpen Access29 Jun 2015
Scientific Reports

Volume: 5, P: 1-12
Correlates of burnout among healthcare workers during the COVID-19 pandemic in South Korea

Soyoon Hwang
Ki Tae Kwon
Ji-yeon Lee
ResearchOpen Access27 Feb 2023
Scientific Reports

Volume: 13, P: 1-16
Two independent variants of epidermal growth factor receptor associated with risk of glioma in a Korean population

In Ki Baek
Hyun Sub Cheong
Hyoung Doo Shin
ResearchOpen Access08 Nov 2022
Scientific Reports

Volume: 12, P: 1-9
The optimal timing of additional surgery after non-curative endoscopic resection to treat early gastric cancer: long-term follow-up study

Jae Hwang Cha
Jie-Hyun Kim
Sung Hoon Noh
ResearchOpen Access04 Dec 2019
Scientific Reports

Volume: 9, P: 1-10
Electrical control of nanoscale functionalization in graphene by the scanning probe technique

Nanoscale functionalized graphenes are fabricated by atomic force microscopy lithography with the desired coverage of a selective functional group using the simple method of the electrical control, and their recovery through moderate thermal treatments. Surprisingly, our controlled coverage of functional groups can reach 94.9% for oxygen and 49.0% for hydrogen, well beyond the coverage achieved by conventional methods.

Ik-Su Byun
Wondong Kim
Bae Ho Park
ResearchOpen Access23 May 2014
NPG Asia Materials

Volume: 6, P: e102
Genome-wide association analysis of copy number variations in subarachnoid aneurysmal hemorrhage

Joon Seol Bae
Hyun Sub Cheong
Hyoung Doo Shin
Research12 Aug 2010
Journal of Human Genetics

Volume: 55, P: 726-730
Atypical Hemolytic Uremic Syndrome Associated With Complement Factor H Autoantibodies and CFHR1/CFHR3 Deficiency

Beom Hee Lee
Soo Heon Kwak
Hae Il Cheong
Research01 Sept 2009
Pediatric Research

Volume: 66, P: 336-340
Association analysis of COMT polymorphisms with schizophrenia and smooth pursuit eye movement abnormality

Byung Lae Park
Hyoung Doo Shin
Sung-Il Woo
Research30 Oct 2009
Journal of Human Genetics

Volume: 54, P: 709-712
Exploring the Novel Susceptibility Gene Variants for Primary Open-Angle Glaucoma in East Asian Cohorts: The GLAU-GENDISK Study

Yong Woo Kim
Yu Jeong Kim
Jin Wook Jeoung
ResearchOpen Access14 Jan 2020
Scientific Reports

Volume: 10, P: 1-9
Hippocampal dentate gyri proteomics reveals Wnt signaling involvement in the behavioral impairment in the THRSP-overexpressing ADHD mouse model

Proteomics in the hippocampal dentate gyri reveal that behavioural impairments in THRSP-overexpressing mice could be regulated by Wnt signalling.

Raly James Perez Custodio
Hee Jin Kim
Jae Hoon Cheong
ResearchOpen Access16 Jan 2023
Communications Biology

Volume: 6, P: 1-17
Self-assembled foam-like graphene networks formed through nucleate boiling

Ho Seon Ahn
Ji-Wook Jang
Jae Sung Lee
ResearchOpen Access07 Mar 2013
Scientific Reports

Volume: 3, P: 1-8
Synchronized affect in shared experiences strengthens social connection

Participants jointly watching a television show exhibit temporal synchrony of facial expressions and electrodermal activity, implying social connection and informing the design of more naturalistic experiments investigating social bonding.

Jin Hyun Cheong
Zainab Molani
Luke J. Chang
ResearchOpen Access28 Oct 2023
Communications Biology

Volume: 6, P: 1-14
Mitochondria damaged by Oxygen Glucose Deprivation can be Restored through Activation of the PI3K/Akt Pathway and Inhibition of Calcium Influx by Amlodipine Camsylate

Hyun-Hee Park
Myung-Hoon Han
Seong-Ho Koh
ResearchOpen Access31 Oct 2019
Scientific Reports

Volume: 9, P: 1-11
Days alive and out of hospital at 30 days and outcomes of off-pump coronary artery bypass grafting

Ah Ran Oh
Seung-Hwa Lee
Hyun Sung Cho
ResearchOpen Access27 Feb 2023
Scientific Reports

Volume: 13, P: 1-9
Independent replication of advanced brain age in mild cognitive impairment and dementia: detection of future cognitive dysfunction

Helmet T. Karim
Howard J. Aizenstein
Sang Joon Son
ResearchOpen Access16 Aug 2022
Molecular Psychiatry

Volume: 27, P: 5235-5243
Cortical thickness is differently associated with ALDH2 rs671 polymorphism according to level of amyloid deposition

Yong Hyuk Cho
Heirim Lee
Sang Joon Son
ResearchOpen Access30 Sept 2021
Scientific Reports

Volume: 11, P: 1-10
Low striatal T3 is implicated in inattention and memory impairment in an ADHD mouse model overexpressing thyroid hormone-responsive protein

Custodio et al. characterise a mouse model of ADHD in which thyroid hormone-responsive protein is overexpressed. They demonstrate that reduced levels of striatal triiodothyronine (T3) play a role in inattention and memory impairment in this model and that the model could be used in future studies examining the predominantly inattentive subtype of ADHD.

Raly James Perez Custodio
Mikyung Kim
Jae Hoon Cheong
ResearchOpen Access20 Sept 2021
Communications Biology

Volume: 4, P: 1-14
RNA sequencing as an alternative tool for detecting measurable residual disease in core-binding factor acute myeloid leukemia

TaeHyung Kim
Joon Ho Moon
Dennis Dong Hwan Kim
ResearchOpen Access18 Nov 2020
Scientific Reports

Volume: 10, P: 1-10
UVB protective effects of Sargassum horneri through the regulation of Nrf2 mediated antioxidant mechanism

Eui Jeong Han
Seo-Young Kim
Ginnae Ahn
ResearchOpen Access11 May 2021
Scientific Reports

Volume: 11, P: 1-10
The frontal skull Hounsfield unit value can predict ventricular enlargement in patients with subarachnoid haemorrhage

Yu Deok Won
Min Kyun Na
Myung-Hoon Han
ResearchOpen Access05 Jul 2018
Scientific Reports

Volume: 8, P: 1-10
Identification of disulfide cross-linked tau dimer responsible for tau propagation

Dohee Kim
Sungsu Lim
Yun Kyung Kim
ResearchOpen Access15 Oct 2015
Scientific Reports

Volume: 5, P: 1-10
Hippocampal Extracellular Signal-Regulated Kinase Signaling has a Role in Passive Avoidance Memory Retrieval Induced by GABA_A Receptor Modulation in Mice

Dong Hyun Kim
Jong Min Kim
Jong Hoon Ryu
Research14 Dec 2011
Neuropsychopharmacology

Volume: 37, P: 1234-1244

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