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Correction: Corrigendum: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

Arun Sreekumar
Laila M. Poisson
Arul M. Chinnaiyan
Amendments and Corrections05 Jun 2013
Nature

Volume: 499, P: 504
HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer

HOXB13 suppresses a lipogenic transcriptional program in prostate cancer (PCa) through HDAC3 recruitment to enhancers. Loss of HOXB13 leads to lipid accumulation in PCa cells, promoting cell motility in vitro and xenograft tumor metastasis in vivo.

Xiaodong Lu
Ka-wing Fong
Jindan Yu
Research25 Apr 2022
Nature Genetics

Volume: 54, P: 670-683
Tomlins et al. reply

Scott A. Tomlins
Bharathi Laxman
Arul M. Chinnaiyan
Research01 Feb 2009
Nature

Volume: 457, P: E2-E3
Cooperativity and equilibrium with FOXA1 define the androgen receptor transcriptional program

The pioneer factor FOXA1 contributes to androgen receptor (AR)-dependent gene expression by opening chromatin to facilitate AR binding. Here, Jin et al.show that because FOXA1 promotes AR association to many low-affinity sites, excessive FOXA1 can lead to reduced AR availability for specific sites.

Hong-Jian Jin
Jonathan C. Zhao
Jindan Yu
Research30 May 2014
Nature Communications

Volume: 5, P: 1-14
TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression

TRIM24 is stabilized in SPOP-mutated prostate cancers, but the regulation of TRIM24 in wild-type prostate cancers is unknown. Here, the authors show that TRIM28 interacts with TRIM24 to prevent SPOP-mediated ubiquitination of TRIM24 and enhances TRIM24 and AR signaling to induce prostate cancer tumorigenesis.

Ka-wing Fong
Jonathan C. Zhao
Jindan Yu
ResearchOpen Access27 Nov 2018
Nature Communications

Volume: 9, P: 1-15
BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1

The polycomb group protein BMI1 is highly expressed in prostate cancer. Here, the authors demonstrate that BMI1 directly interacts with AR leading to increased AR signaling independently of PRC1 complex and that targeting BMI1 inhibits tumor growth of castration-resistant prostate cancer tumors.

Sen Zhu
Dongyu Zhao
Qi Cao
ResearchOpen Access05 Feb 2018
Nature Communications

Volume: 9, P: 1-13
Palmitoyl acyltransferase ZDHHC7 inhibits androgen receptor and suppresses prostate cancer

Zhuoyuan Lin
Shivani Agarwal
Jindan Yu
Research17 May 2023
Oncogene

Volume: 42, P: 2126-2138
FOXA1 inhibits hypoxia programs through transcriptional repression of HIF1A

Xiaohai Wang
Lourdes Brea
Jindan Yu
Research05 Aug 2022
Oncogene

Volume: 41, P: 4259-4270
Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

Distinct translocation mechanisms and additional translocation partners for ETS genes are found in prostate cancer. This study also provides the first functional evidence that ETS gene deregulation can promote cancer cell invasion in cell lines and pre-malignant prostate lesions in a transgenic mouse model.

Scott A. Tomlins
Bharathi Laxman
Arul M. Chinnaiyan
Research02 Aug 2007
Nature

Volume: 448, P: 595-599
Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

A systematic analysis of metabolites in prostate cancer samples has led to the identification of sarcosine as a putative biomarker detectable in urine, which could potentially be used to aid prostate cancer diagnosis. Sarcosine promotes the invasion of prostate cancer cells and may play a role in metastasis.

Arun Sreekumar
Laila M. Poisson
Arul M. Chinnaiyan
Research01 Feb 2009
Nature

Volume: 457, P: 910-914
Targeting the cochlin/SFRP1/CaMKII axis in the ocular posterior pole prevents the progression of nonpathologic myopia

A proteomics study using Guinea Pig ocular posterior pole tissues identifies a novel axis composed of cochlin in the retina, SFRP1 in the RPE, and CaMKII in choroidal vascular endothelial cells responsible for non-pathologic myopia.

Chao Geng
Siyi Liu
Yan Zhang
ResearchOpen Access29 Aug 2023
Communications Biology

Volume: 6, P: 1-19
Interferon regulatory factor-1 activates autophagy to aggravate hepatic ischemia-reperfusion injury via the P38/P62 pathway in mice

Yao Yu
Shipeng Li
Zhijun Zhu
ResearchOpen Access07 Mar 2017
Scientific Reports

Volume: 7, P: 1-12
Myeloid differentiation factor-2/LY96, a potential predictive biomarker of metastasis and poor outcomes in prostate cancer: clinical implications as a potential therapeutic target

Marina G. Ferrari
Alexis P. Jimenez-Uribe
Adrian P. Mansini
ResearchOpen Access23 Dec 2023
Oncogene

Volume: 43, P: 484-494
The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer

J Yu
Q Cao
A M Chinnaiyan
Research12 Jul 2010
Oncogene

Volume: 29, P: 5370-5380
Altered chromatin recruitment by FOXA1 mutations promotes androgen independence and prostate cancer progression

Bohan Xu
Bing Song
Jindan Yu
Correspondence19 Jul 2019
Cell Research

Volume: 29, P: 773-775
The long non-coding RNA keratin-7 antisense acts as a new tumor suppressor to inhibit tumorigenesis and enhance apoptosis in lung and breast cancers

Zhe Zhao
Mei Meng
Quansheng Zhou
ResearchOpen Access25 Apr 2023
Cell Death & Disease

Volume: 14, P: 1-16
BMI1 is directly regulated by androgen receptor to promote castration-resistance in prostate cancer

Sen Zhu
Dongyu Zhao
Qi Cao
Research28 Aug 2019
Oncogene

Volume: 39, P: 17-29
CXCR7 as a novel therapeutic target for advanced prostate cancer

Galina Gritsina
Jindan Yu
Reviews09 Feb 2023
Oncogene

Volume: 42, P: 785-792
Going beyond Polycomb: EZH2 functions in prostate cancer

Su H. Park
Ka-Wing Fong
Jindan Yu
Reviews04 Aug 2021
Oncogene

Volume: 40, P: 5788-5798
A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis

Shuying Shen
Xiaocan Guo
Bin Zhao
ResearchOpen Access14 Aug 2015
Cell Research

Volume: 25, P: 997-1012
CCN3/NOV gene expression in human prostate cancer is directly suppressed by the androgen receptor

L Wu
C Runkle
J Yu
Research14 Jan 2013
Oncogene

Volume: 33, P: 504-513
TMPRSS2–ERG gene fusions induce prostate tumorigenesis by modulating microRNA miR-200c

J Kim
L Wu
J Yu
Research04 Nov 2013
Oncogene

Volume: 33, P: 5183-5192
FOXA1 inhibits prostate cancer neuroendocrine differentiation

J Kim
H Jin
J Yu
Research20 Mar 2017
Oncogene

Volume: 36, P: 4072-4080
FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

J C Zhao
K-W Fong
J Yu
Research11 Jan 2016
Oncogene

Volume: 35, P: 4335-4344
LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer

X Xue
Y A Yang
J Yu
Research14 Sept 2015
Oncogene

Volume: 35, P: 2746-2755

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Correction: Corrigendum: Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer

Tomlins et al. reply

Cooperativity and equilibrium with FOXA1 define the androgen receptor transcriptional program

TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression

BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1

Palmitoyl acyltransferase ZDHHC7 inhibits androgen receptor and suppresses prostate cancer

FOXA1 inhibits hypoxia programs through transcriptional repression of HIF1A

Distinct classes of chromosomal rearrangements create oncogenic ETS gene fusions in prostate cancer

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression

Targeting the cochlin/SFRP1/CaMKII axis in the ocular posterior pole prevents the progression of nonpathologic myopia

Interferon regulatory factor-1 activates autophagy to aggravate hepatic ischemia-reperfusion injury via the P38/P62 pathway in mice

Myeloid differentiation factor-2/LY96, a potential predictive biomarker of metastasis and poor outcomes in prostate cancer: clinical implications as a potential therapeutic target

The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer

Altered chromatin recruitment by FOXA1 mutations promotes androgen independence and prostate cancer progression

The long non-coding RNA keratin-7 antisense acts as a new tumor suppressor to inhibit tumorigenesis and enhance apoptosis in lung and breast cancers

BMI1 is directly regulated by androgen receptor to promote castration-resistance in prostate cancer

CXCR7 as a novel therapeutic target for advanced prostate cancer

Going beyond Polycomb: EZH2 functions in prostate cancer

A miR-130a-YAP positive feedback loop promotes organ size and tumorigenesis

CCN3/NOV gene expression in human prostate cancer is directly suppressed by the androgen receptor

TMPRSS2–ERG gene fusions induce prostate tumorigenesis by modulating microRNA miR-200c

FOXA1 inhibits prostate cancer neuroendocrine differentiation

FOXA1 acts upstream of GATA2 and AR in hormonal regulation of gene expression

LncRNA HOTAIR enhances ER signaling and confers tamoxifen resistance in breast cancer

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