Nature Search

Research on dimension measurement algorithm for parcel boxes in high-speed sorting system

Ning Dai
Jingchao Chen
Yanhong Yuan
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-15
Multi-omics data integration using ratio-based quantitative profiling with Quartet reference materials

Multi-omics data are readily integrated using quartet reference materials.

Yuanting Zheng
Yaqing Liu
Leming Shi
ResearchOpen Access07 Sept 2023
Nature Biotechnology

Volume: 42, P: 1133-1149
Precision cancer sono-immunotherapy using deep-tissue activatable semiconducting polymer immunomodulatory nanoparticles

To improve the specificity of immunotherapy, here the authors report the design of a semiconducting polymer immunomodulatory nanoparticle with sonodynamic process to remotely release immune-modulators for deep-tissue precision cancer sono-immunotherapy.

Jingchao Li
Yu Luo
Ruiping Zhang
ResearchOpen Access12 Jul 2022
Nature Communications

Volume: 13, P: 1-15
Donor–acceptor mutually diluted heterojunctions for layer-by-layer fabrication of high-performance organic solar cells

Wang et al. show that a small amount of donor in the acceptor layer or vice versa induces structural order owing to dipole–dipole interaction between the donor and the acceptor, enabling a certified efficiency of 19.1% in pseudo-bilayer organic solar cells.

Liang Wang
Chen Chen
Tao Wang
Research09 Jan 2024
Nature Energy

Volume: 9, P: 208-218
Autophagy-deficient macrophages exacerbate cisplatin-induced mitochondrial dysfunction and kidney injury via miR-195a-5p-SIRT3 axis

Tubulointerstitial inflammation occurs frequently in acute kidney injury (AKI), and Mφ autophagy is a known contributor to inflammation-related diseases. Here, Yuan et al. show that Mφ autophagy deficiency induces systemic inflammation, impairs mitochondria, and worsens kidney injury in AKI mice.

Yujia Yuan
Longhui Yuan
Yanrong Lu
ResearchOpen Access23 May 2024
Nature Communications

Volume: 15, P: 1-17
Two-year efficacy and safety of different anti-vascular endothelial growth factor regimens for neovascular age-related macular degeneration: a network meta-analysis of randomized controlled trials

Hong Sun
Ling Li
Taomin Huang
Research11 Sept 2024
Eye

Volume: 38, P: 3473-3480
Transformable hybrid semiconducting polymer nanozyme for second near-infrared photothermal ferrotherapy

Due to tumour microenvironment, Fenton reactions have low therapeutic efficiency. Here the authors report on the application of NIR-II hybrid semiconducting nanozymes for combined photothermal therapy and enhanced ferrotherapy with photoacoustic imaging and show application in vivo in tumour models.

Yuyan Jiang
Xuhui Zhao
Ruiping Zhang
ResearchOpen Access20 Apr 2020
Nature Communications

Volume: 11, P: 1-13
Alcohol consumption and risks of more than 200 diseases in Chinese men

Observational analyses from the China Kadoorie Biobank found that alcohol consumption was associated with higher risks of 61 diseases in Chinese men, with most of these associations confirmed by genetic analyses.

Pek Kei Im
Neil Wright
Xiaoyi Zhang
ResearchOpen Access08 Jun 2023
Nature Medicine

Volume: 29, P: 1476-1486
Tryptophan derivatives regulate the transcription of Oct4 in stem-like cancer cells

The aryl hydrocarbon receptor, AhR, can regulate Oct4, which is often expressed in cancer stem cells and promotes pluripotency and tumorigenesis. Here, in cancer stem cells, AhR is shown to be activated by the tryptophan derivative ITE, which causes transcriptional repression of Oct4 and reduced tumorigenesis.

Jie Cheng
Wenxin Li
Ying-Jie Wang
ResearchOpen Access10 Jun 2015
Nature Communications

Volume: 6, P: 1-13
Molecular optical imaging probes for early diagnosis of drug-induced acute kidney injury

Chemiluminescent molecular renal probes have been developed and are shown to be capable of non-invasive real-time imaging of early-stage oxidative stress biomarkers of drug-induced acute kidney injury, and high renal clearance.

Jiaguo Huang
Jingchao Li
Kanyi Pu
Research27 May 2019
Nature Materials

Volume: 18, P: 1133-1143
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation

Zhang, Xu, Liu, Wang et al. identify an inhibitory mechanism for RIPK1 kinase through EGLN1/pVHL-mediated proline hydroxylation, which is disrupted upon prolonged hypoxia that activates RIPK1 activity to promote cell death and inflammation.

Tao Zhang
Daichao Xu
Wenyi Wei
Research03 Jul 2023
Nature Cell Biology

Volume: 25, P: 950-962
EPHA5 promotes cell proliferation and inhibits apoptosis in Follicular Thyroid Cancer via the STAT3 signaling pathway

Guorong Wang
Gaoran Xu
Yongfu Zhao
ResearchOpen Access22 Apr 2025
Oncogenesis

Volume: 14, P: 1-12
Semiconducting polymer nano-PROTACs for activatable photo-immunometabolic cancer therapy

Proteolysis targeting chimeras (PROTACs) is an effective alternative to modulate protein homeostasis but can lead to uncontrollable protein degradation and off-target side effects. Here, the authors developed semiconducting polymer nano-PROTACs with phototherapeutic and activatable protein degradation abilities for photo-immunometabolic cancer therapy.

Chi Zhang
Ziling Zeng
Kanyi Pu
ResearchOpen Access18 May 2021
Nature Communications

Volume: 12, P: 1-12
Three-dimensional radio-frequency transformers based on a self-rolled-up membrane platform

On-chip radio-frequency transformers made from three-dimensional self-rolled-up coils offer both high performance and an ultra-compact device footprint.

Wen Huang
Jingchao Zhou
Xiuling Li
Research14 May 2018
Nature Electronics

Volume: 1, P: 305-313
OTX2 restricts entry to the mouse germline

The transcription factor OTX2 ensures that germline induction is initially kept in check and only proceeds after OTX2 downregulation.

Jingchao Zhang
Man Zhang
Ian Chambers
Research03 Oct 2018
Nature

Volume: 562, P: 595-599
The implications of dust ice nuclei effect on cloud top temperature in a complex mesoscale convective system

Rui Li
Xue Dong
Qilong Min
ResearchOpen Access23 Oct 2017
Scientific Reports

Volume: 7, P: 1-9
Catalytical nano-immunocomplexes for remote-controlled sono-metabolic checkpoint trimodal cancer therapy

Ultrasound-based therapies in combination with immune checkpoint blockade have been shown to improve the efficacy of cancer immunotherapy. Here the authors report the design of a pH-responsive and sono-irradiation activatable nanosystem functionalized with anti-PD-L1 and adenosine deaminase for sono-metabolic cancer immunotherapy.

Chi Zhang
Jingsheng Huang
Kanyi Pu
ResearchOpen Access16 Jun 2022
Nature Communications

Volume: 13, P: 1-15
A generic approach towards afterglow luminescent nanoparticles for ultrasensitive in vivo imaging

Afterglow luminescence is used to reduce background noise and increase sensitivity; however, biocompatible afterglow materials are limited. Here, the authors report on an approach to turn standard optical agents into afterglow nanoparticles and demonstrate the application in tumour imagining in vivo.

Yuyan Jiang
Jiaguo Huang
Kanyi Pu
ResearchOpen Access02 May 2019
Nature Communications

Volume: 10, P: 1-10
PINCH-1 regulates mitochondrial dynamics to promote proline synthesis and tumor growth

Proline metabolism is crucial to tumor proliferation. Here, the authors show PINCH-1 deficiency inhibited proline synthesis by promoting mitochondrial fragmentation via DRP1, downregulating PYCR1 expression and reducing cell proliferation in vitro and in vivo.

Ling Guo
Chunhong Cui
Chuanyue Wu
ResearchOpen Access01 Oct 2020
Nature Communications

Volume: 11, P: 1-20
Graphene surface plasmons at the near-infrared optical regime

Qiming Zhang
Xiangping Li
Min Gu
ResearchOpen Access09 Oct 2014
Scientific Reports

Volume: 4, P: 1-6
Highly responsive MoS₂ photodetectors enhanced by graphene quantum dots

Caiyun Chen
Hong Qiao
Qiaoliang Bao
ResearchOpen Access03 Jul 2015
Scientific Reports

Volume: 5, P: 1-9
Causal associations of blood lipids with risk of ischemic stroke and intracerebral hemorrhage in Chinese adults

In a nested case-control study from the China Kadoorie Biobank, lowering blood low-density lipoprotein cholesterol levels confers lower risk for ischemic stroke but elevated risk for intracerebral hemorrhage, which was confirmed by genetic Mendelian randomization analyses.

Luanluan Sun
Robert Clarke
Zhe Qiu
Research11 Mar 2019
Nature Medicine

Volume: 25, P: 569-574
Identification of Anoikis-related potential biomarkers and therapeutic drugs in chronic thromboembolic pulmonary hypertension via bioinformatics analysis and in vitro experiment

Haijia Yu
Huihui Song
Lijie Qin
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-15
Long- and short-run asymmetric impacts of climate variation on tuberculosis based on a time series study

Yongbin Wang
Chenlu Xue
Fei Lin
ResearchOpen Access09 Oct 2024
Scientific Reports

Volume: 14, P: 1-13
Towards precision medicine based on a continuous deep learning optimization and ensemble approach

Jian Li
Linyuan Jin
Jieke Liao
ResearchOpen Access03 Feb 2023
npj Digital Medicine

Volume: 6, P: 1-11
Urinary profiles of luteinizing hormone, estrogen and progestagen during the estrous and gestational periods in giant pandas (Ailuropda melanoleuca)

Kailai Cai
Shangmian Yie
Rong Hou
ResearchOpen Access16 Jan 2017
Scientific Reports

Volume: 7, P: 1-10
Effects of soil nitrogen (N) deficiency on photosynthetic N-use efficiency in N-fixing and non-N-fixing tree seedlings in subtropical China

Jingchao Tang
Baodi Sun
Mauro Centritto
ResearchOpen Access14 Mar 2019
Scientific Reports

Volume: 9, P: 1-14
Possible mechanisms of control of Fusarium wilt of cut chrysanthemum by Phanerochaete chrysosporium in continuous cropping fields: A case study

Ping Li
Jingchao Chen
Hailei Wang
ResearchOpen Access22 Nov 2017
Scientific Reports

Volume: 7, P: 1-13
Secretory products from epicardial adipose tissue induce adverse myocardial remodeling after myocardial infarction by promoting reactive oxygen species accumulation

Shuang Hao
Xin Sui
Zhenxing Liang
ResearchOpen Access13 Sept 2021
Cell Death & Disease

Volume: 12, P: 1-11
Dynamic modeling and simulation of rigid-flexible coupling cable system by absolute nodal coordinate formulation

Xiaoyu Wang
Jingchao Zhao
Qingkai Han
ResearchOpen Access09 Aug 2022
Scientific Reports

Volume: 12, P: 1-14
Inhibitory effects of autoantibodies on the muscarinic receptors in Sjögren's syndrome

Jingchao Li
Young-Min Ha
Kyungpyo Park
Research27 Sept 2004
Laboratory Investigation

Volume: 84, P: 1430-1438
Sensory sensitivity and intelligence are correlated with nutrient deficiency in children with autism spectrum disorder and intellectual disability

Tingkai Cui
Jingchao Zhang
Xin Zhang
Research17 Nov 2023
European Journal of Clinical Nutrition

Volume: 78, P: 286-294
Utility of single versus sequential measurements of risk factors for prediction of stroke in Chinese adults

Matthew Chun
Robert Clarke
Libo Zhang
ResearchOpen Access02 Sept 2021
Scientific Reports

Volume: 11, P: 1-10
Integrated multi-omics reveal important roles of gut contents in intestinal ischemia–reperfusion induced injuries in rats

Die Dai et al. evaluate changes in the metabolomic and gut microbiome in response to experimental intestinal ischemia reperfusion (IIR) injury in rats. Their results provide further insight into how gut contents contribute to widespread injury in IIR patients.

Die Dai
Fandie Dai
Wei-Hua Chen
ResearchOpen Access09 Sept 2022
Communications Biology

Volume: 5, P: 1-15
Estimating the COVID-19 prevalence and mortality using a novel data-driven hybrid model based on ensemble empirical mode decomposition

Yongbin Wang
Chunjie Xu
Yuchun Li
ResearchOpen Access01 Nov 2021
Scientific Reports

Volume: 11, P: 1-17
The long-term effects of meteorological parameters on pertussis infections in Chongqing, China, 2004–2018

Yongbin Wang
Chunjie Xu
Sanqiao Yao
ResearchOpen Access14 Oct 2020
Scientific Reports

Volume: 10, P: 1-12
LSD1-mediated demethylation of OCT4 safeguards pluripotent stem cells by maintaining the transcription of PORE-motif-containing genes

Songsong Dan
Yuelin Song
Bo Kang
ResearchOpen Access13 May 2021
Scientific Reports

Volume: 11, P: 1-14
Time series analysis of temporal trends in hemorrhagic fever with renal syndrome morbidity rate in China from 2005 to 2019

Yongbin Wang
Chunjie Xu
Sanqiao Yao
ResearchOpen Access15 Jun 2020
Scientific Reports

Volume: 10, P: 1-13
Systemic inflammation is associated with incident stroke and heart disease in East Asians

Mohd A. Karim
Christiana Kartsonaki
Libo Zhang
ResearchOpen Access27 Mar 2020
Scientific Reports

Volume: 10, P: 1-11
Dietary resources shape the adaptive changes of cyanide detoxification function in giant panda (Ailuropoda melanoleuca)

He Huang
Shangmian Yie
Zhihe Zhang
ResearchOpen Access05 Oct 2016
Scientific Reports

Volume: 6, P: 1-11
Multifunctional Fe₃O₄ @ Au core/shell nanostars: a unique platform for multimode imaging and photothermal therapy of tumors

Yong Hu
Ruizhi Wang
Xiangyang Shi
ResearchOpen Access21 Jun 2016
Scientific Reports

Volume: 6, P: 1-12
Publisher Correction: Utility of single versus sequential measurements of risk factors for prediction of stroke in Chinese adults

Matthew Chun
Robert Clarke
Libo Zhang
Amendments and CorrectionsOpen Access18 Oct 2021
Scientific Reports

Volume: 11, P: 1
miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway

Leilei Liang
Chengshun Gao
Yongfu Zhao
ResearchOpen Access03 Aug 2017
Cell Death & Disease

Volume: 8, P: e2968
Publisher Correction: Systemic inflammation is associated with incident stroke and heart disease in East Asians

Mohd A. Karim
Christiana Kartsonaki
Libo Zhang
Amendments and CorrectionsOpen Access12 May 2020
Scientific Reports

Volume: 10, P: 1-2

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