The meiocyte-specific histone reader MMD1 competes with the C-terminal ___domain of the histone demethylase JMJ16 for binding to its catalytic ___domain, expanding the substrate specificity of JMJ16 from H3K4 alone in somatic cells to both H3K4 and H3K9 in meiocytes.
- Jun Wang
- Chaoyi Yu
- Yingxiang Wang