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Showing 1–5 of 5 results
Advanced filters: Author: Jonathan D. Colburn Clear advanced filters

  • Bacterial cell shape is dependent on the formation of the extracellular sugar polymer called peptidoglycan. Here the authors describe RodA-PBP2, the enzymatic core of the elongasome, which is the complex responsible peptidoglycan synthesis, and utilize an integrated approach to investigate the mechanism of peptidoglycan biosynthesis.

    • Rie Nygaard
    • Chris L. B. Graham
    • Filippo Mancia
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-15

  • Integrins are key modulators of cell adhesion and signaling. Here the authors show, unexpectedly, that a complex of integrins and the lipid 25-hydroxycholesterol induces FAK activation and proinflammatory cytokine production, thereby serving as an integral part of innate immunity regulation.

    • Swechha M. Pokharel
    • Niraj K. Shil
    • Santanu Bose
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-17