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Showing 1–50 of 83 results

Advanced filters: Author: Junji Takeda Clear advanced filters

Inhibition of Mouse Sarcoma 180 by Polysaccharides from Lentinus edodes (Berk.) Sing.

GORO CHIHARA
YUKIKO MAEDA
FUMIKO FUKUOKA
Research17 May 1969
Nature

Volume: 222, P: 687-688
A novel protein that participates in nonself discrimination of malignant cells by homologous complement

Misako Matsumoto
Junji Takeda
Tsukasa Seya
Research01 Nov 1997
Nature Medicine

Volume: 3, P: 1266-1270
Expression of functional human interleukin-2 receptor in mouse T cells by cDNA transfection

Shigeru Kondo
Akira Shimizu
Tasuku Honjo
Research06 Mar 1986
Nature

Volume: 320, P: 75-77
Molecular cloning of cDNA encoding human interleukin-2 receptor

Toshio Nikaido
Akira Shimizu
Tasuku Honjo
Research18 Oct 1984
Nature

Volume: 311, P: 631-635
Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies

An observational study on a large cohort of patients with gastrointestinal cancer demonstrates the utility of ctDNA analysis for accelerating the enrollment of patients in clinical trials with no accompanying deterioration in treatment efficacy.

Yoshiaki Nakamura
Hiroya Taniguchi
Takayuki Yoshino
Research05 Oct 2020
Nature Medicine

Volume: 26, P: 1859-1864
TP53 and CDKN2A alterations define a poor prognostic subgroup in patients with nodal T follicular helper cell lymphoma

Yuta Ito
Joji Shimono
Masao Nakagawa
Research02 May 2025
Leukemia

Volume: 39, P: 1723-1734
Optically Active Polysilanes. Ten Years of Progress and New Polymer Twist for Nanoscience and Nanotechnology

Michiya Fujiki
Julian Robert Koe
Junji Watanabe
Reviews01 Apr 2003
Polymer Journal

Volume: 35, P: 297-344
Modeling NK-cell lymphoma in mice reveals its cell-of-origin and microenvironmental changes and identifies therapeutic targets

Extranodal NK/T-cell lymphoma (ENKTCL) is an aggressive Epstein-Barr virus (EBV)-related neoplasm. Here the authors report a genetically engineered mouse model harboring NK-cellspecific Trp53 deletion to model ENKTCL in mice

Junji Koya
Tomohiko Tanigawa
Keisuke Kataoka
ResearchOpen Access22 Oct 2024
Nature Communications

Volume: 15, P: 1-15
Molecular basis of lipid transfer protein deficiency in a family with increased high-density lipoproteins

Maryanne L. Brown
Akihiro Inazu
Alan R. Tall
Research01 Nov 1989
Nature

Volume: 342, P: 448-451
Genetic architecture of the inflammatory bowel diseases across East Asian and European ancestries

Genome-wide association analyses across individuals of East Asian and European ancestries identify new risk loci for inflammatory bowel diseases. A polygenic risk score derived from the combined datasets shows improved prediction accuracy.

Zhanju Liu
Ruize Liu
Hailiang Huang
Research08 May 2023
Nature Genetics

Volume: 55, P: 796-806
Cases of Neuroblastoma Missed by the Mass Screening Programs

Motoi Nishi
Hirotsugu Miyake
Tsuneaki Kawai
Research01 Dec 1989
Pediatric Research

Volume: 26, P: 603-604
Genome-wide phenotype analysis in ES cells by regulated disruption of Bloom's syndrome gene

Kosuke Yusa
Kyoji Horie
Junji Takeda
Research24 Jun 2004
Nature

Volume: 429, P: 896-899
Author Correction: A newly identified gene Ahed plays essential roles in murine haematopoiesis

Ritsuko Nakai
Takafumi Yokota
Junji Takeda
Amendments and CorrectionsOpen Access23 Oct 2024
Nature Communications

Volume: 15, P: 1
A newly identified gene Ahed plays essential roles in murine haematopoiesis

Here, authors screening mutant embryonic stem cells and identify a new gene termed ‘attenuated hematopoietic development (Ahed)’, which encodes a nuclear protein. Ahed is shown to be essential lifelong hematopoiesis.

Ritsuko Nakai
Takafumi Yokota
Junji Takeda
ResearchOpen Access25 Jun 2024
Nature Communications

Volume: 15, P: 1-16
Presenilin-1 mutations downregulate the signalling pathway of the unfolded-protein response

Taiichi Katayama
Kazunori Imaizumi
Masaya Tohyama
Research29 Oct 1999
Nature Cell Biology

Volume: 1, P: 479-485
A homozygous mutant embryonic stem cell bank applicable for phenotype-driven genetic screening

This paper describes a method to enrich for homozygous mutant mouse embryonic stem cells without an inherently selectable phenotype. It is used to construct a bank of homozygous and heterozygous mutant cells and should prove useful for cellular phenotypic screens.

Kyoji Horie
Chikara Kokubu
Junji Takeda
Research23 Oct 2011
Nature Methods

Volume: 8, P: 1071-1077
Enhanced insulin sensitivity, energy expenditure and thermogenesis in adipose-specific Pten suppression in mice

Nobuyasu Komazawa
Morihiro Matsuda
Iichiro Shimomura
Research17 Oct 2004
Nature Medicine

Volume: 10, P: 1208-1215
Characterization and reduction of non-endocrine cells accompanying islet-like endocrine cells differentiated from human iPSC

Hideyuki Hiyoshi
Kensuke Sakuma
Taro Toyoda
ResearchOpen Access18 Mar 2022
Scientific Reports

Volume: 12, P: 1-13
Transposon-tagged mutagenesis in the rat

Kazuhiro Kitada
Satoshi Ishishita
Junji Takeda
Research14 Jan 2007
Nature Methods

Volume: 4, P: 131-133
Novel Conjugated Polymer Containing Anthracene Backbone: Competitive Addition Polymerization of Dithiol Monomers to Diethynyl Monomers and Relative Reactivity

Eiichi Kobayashi
Jian Jiang
Junji Furukawa
Research01 Feb 1990
Polymer Journal

Volume: 22, P: 146-152
Novel Conjugated Polymer Containing Anthracene Backbone: Addition Polymers of 1,4-Benzenedithiol with 9,10-Diethynylanthracene and Its Conductivity

Eiichi Kobayashi
Jian Jiang
Junji Furukawa
Research01 Mar 1990
Polymer Journal

Volume: 22, P: 266-273
A synthetic enamel for rapid tooth repair

Seamless fixing of an early caries lesion can be achieved without prior excavation.

Kazue Yamagishi
Kazuo Onuma
Pisol Senawangse
Research23 Feb 2005
Nature

Volume: 433, P: 819
A comparative study of curated contents by knowledge-based curation system in cancer clinical sequencing

Kazuko Sakai
Masayuki Takeda
Kazuto Nishio
ResearchOpen Access05 Aug 2019
Scientific Reports

Volume: 9, P: 1-8
Angiotensin-converting enzyme is a GPI-anchored protein releasing factor crucial for fertilization

Gen Kondoh
Hiromasa Tojo
Junji Takeda
Research23 Jan 2005
Nature Medicine

Volume: 11, P: 160-166
Region-specific saturation germline mutagenesis in mice using the Sleeping Beauty transposon system

Vincent W Keng
Kojiro Yae
Junji Takeda
Research22 Sept 2005
Nature Methods

Volume: 2, P: 763-769
Loss of mammalian Sprouty2 leads to enteric neuronal hyperplasia and esophageal achalasia

Takaharu Taketomi
Daigo Yoshiga
Akihiko Yoshimura
Research05 Jun 2005
Nature Neuroscience

Volume: 8, P: 855-857
The clinical outcomes of combination chemotherapy in elderly patients with advanced biliary tract cancer: an exploratory analysis of JCOG1113

Ikuhiro Yamada
Chigusa Morizane
Junji Furuse
ResearchOpen Access19 Jan 2022
Scientific Reports

Volume: 12, P: 1-9
Tumor B7-H3 expression in diagnostic biopsy specimens and survival in patients with metastatic prostate cancer

Gulanbar Amori
Emiko Sugawara
Kentaro Inamura
Research08 Feb 2021
Prostate Cancer and Prostatic Diseases

Volume: 24, P: 767-774
Significance of inflammatory indexes in atezolizumab monotherapy outcomes in previously treated non-small-cell lung cancer patients

Yuki Katayama
Tadaaki Yamada
Koichi Takayama
ResearchOpen Access15 Oct 2020
Scientific Reports

Volume: 10, P: 1-9
Renal function is associated with blood neurofilament light chain level in older adults

Shoshin Akamine
Noriko Marutani
Takashi Kudo
ResearchOpen Access23 Nov 2020
Scientific Reports

Volume: 10, P: 1-7
CRISPR-Cas3 induces broad and unidirectional genome editing in human cells

Class 1 CRISPR systems are not as developed for genome editing as Class 2 systems are. Here the authors show that Cas3 can be used to generate functional knockouts and knock-ins, as well as Cas3-mediated exon-skipping in DMD cells.

Hiroyuki Morisaka
Kazuto Yoshimi
Tomoji Mashimo
ResearchOpen Access06 Dec 2019
Nature Communications

Volume: 10, P: 1-13
Transparent semiconducting SrTiO₃ crystal fabricated by heating treatment with gaseous ammonia and CeO₂ powder

Yuka Morimoto
Junji Nishiyama
Takuya Hoshina
ResearchOpen Access22 Mar 2018
Scientific Reports

Volume: 8, P: 1-7
Novel Conjugated Polymer Containing Aromatic Ring and Selenium in Backbone. Side Reactions in the Addition Polymerization of Benzenediselenol to Diethynylbenzene

Eiichi Kobayashi
Nobuki Metaka
Junji Furukawa
Research01 Feb 1995
Polymer Journal

Volume: 27, P: 147-155
Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon

piggyBac transposons carrying reprogramming factors are used to reprogram mouse embryonic fibroblasts, with efficiencies equivalent to retroviral transduction, and then removed from the induced pluripotent state cell genome without a trace.

Kosuke Yusa
Roland Rad
Allan Bradley
Research31 Mar 2009
Nature Methods

Volume: 6, P: 363-369
Microwell bag culture for large-scale production of homogeneous islet-like clusters

Ryo Suenaga
Shuhei Konagaya
Taro Toyoda
ResearchOpen Access25 Mar 2022
Scientific Reports

Volume: 12, P: 1-11
Triglyceride/high density lipoprotein cholesterol index and future cardiovascular events in diabetic patients without known cardiovascular disease

Ryosuke Nakashima
Shota Ikeda
Kohtaro Abe
ResearchOpen Access17 Mar 2025
Scientific Reports

Volume: 15, P: 1-10
CD98 heavy chain protein is overexpressed in non-small cell lung cancer and is a potential target for CAR T-cell therapy

Moto Yaga
Kana Hasegawa
Naoki Hosen
ResearchOpen Access02 Aug 2024
Scientific Reports

Volume: 14, P: 1-12
VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination

The vascular cell adhesion molecule VCAM1 plays a role in the immune system but is also expressed in oligodendrocytes. Here, the authors find VCAM1 interacts with neuronal α4 integrin to regulate oligodendrocyte differentiation and thereby myelination, an effect mediated by downstream CD69 signalling.

Yuki Miyamoto
Tomohiro Torii
Junji Yamauchi
ResearchOpen Access23 Nov 2016
Nature Communications

Volume: 7, P: 1-16
Long-term effects of ipragliflozin on blood pressure in patients with type 2 diabetes: insights from the randomized PROTECT trial

Yuichi Saito
Atsushi Tanaka
Kosuke Nishio
Research14 Nov 2023
Hypertension Research

Volume: 47, P: 168-176
A tardive dyskinesia drug target VMAT-2 participates in neuronal process elongation

Miki Ishida
Ryuya Ichikawa
Junji Yamauchi
ResearchOpen Access08 Apr 2025
Scientific Reports

Volume: 15, P: 1-13
Probing consequences of anion-dictated electrochemistry on the electrode/monolayer/electrolyte interfacial properties

Conveying electrochemistry in terms of the electrode/electrolyte interfacial properties remains challenging. Here, the authors employ a surface-bound molecular probe and photoelectron spectroscopy to peer into the anion-dictated and potential-induced interfacial electronic and structural properties.

Raymond A. Wong
Yasuyuki Yokota
Yousoo Kim
ResearchOpen Access21 Aug 2020
Nature Communications

Volume: 11, P: 1-9
Aggressive natural killer-cell leukemia mutational landscape and drug profiling highlight JAK-STAT signaling as therapeutic target

Aggressive natural killer-cell leukemia (ANKL) has few targeted therapies. Here ANKL patients are reported to harbor STAT3, RAS-MAPK pathway, DDX3X and epigenetic modifier mutations; and drug sensitivity profiling uncovers the importance of the JAK-STAT pathway, revealing potential ANKL therapeutic targets.

Olli Dufva
Matti Kankainen
Satu Mustjoki
ResearchOpen Access19 Apr 2018
Nature Communications

Volume: 9, P: 1-12
Imaging intraorganellar Ca²⁺ at subcellular resolution using CEPIA

The use of intracellular calcium sensors provides important information about the dynamics of calcium signalling in cells. Here Suzuki et al. develop organelle-targeted sensors to simultaneously measure calcium concentrations in ER and mitochondria, and uncover novel insights into calcium flux in mitochondria.

Junji Suzuki
Kazunori Kanemaru
Masamitsu Iino
ResearchOpen Access13 Jun 2014
Nature Communications

Volume: 5, P: 1-13
HER3 activation contributes toward the emergence of ALK inhibitor-tolerant cells in ALK-rearranged lung cancer with mesenchymal features

Keiko Tanimura
Tadaaki Yamada
Koichi Takayama
ResearchOpen Access18 Jan 2022
npj Precision Oncology

Volume: 6, P: 1-12
Blood pressure during long-term cilostazol-based dual antiplatelet therapy after stroke: a post hoc analysis of the CSPS.com trial

Kazunori Toyoda
Masatoshi Koga
Hiroaki Tanaka
ResearchOpen Access09 Jul 2024
Hypertension Research

Volume: 47, P: 2238-2249
A transposon-based chromosomal engineering method to survey a large cis-regulatory landscape in mice

Kokubu and colleagues have developed a method for mapping cis-regulatory elements in the mouse using targeted integration of the Sleeping Beauty transposon. This method also gives researchers the ability to generate targeted deletions for testing loss-of-function effects.

Chikara Kokubu
Kyoji Horie
Junji Takeda
Research26 Jul 2009
Nature Genetics

Volume: 41, P: 946-952
Long term prognosis in patients with pulmonary hypertension undergoing catheter ablation for supraventricular tachycardia

Hiroyuki Kamada
Junji Kaneyama
Kengo Kusano
ResearchOpen Access10 Aug 2021
Scientific Reports

Volume: 11, P: 1-9
Red fluorescent CEPIA indicators for visualization of Ca²⁺ dynamics in mitochondria

Kazunori Kanemaru
Junji Suzuki
Masamitsu Iino
ResearchOpen Access18 Feb 2020
Scientific Reports

Volume: 10, P: 1-9
Outcomes of allogeneic hematopoietic stem cell transplantation for relapsed or refractory diffuse large B-cell lymphoma

Koji Kato
Takeshi Sugio
Ritsuro Suzuki
Research15 Dec 2023
Bone Marrow Transplantation

Volume: 59, P: 306-314
A Phase 2 study of nivolumab in combination with modified FOLFIRINOX for metastatic pancreatic cancer

Chigusa Morizane
Makoto Ueno
Junji Furuse
ResearchOpen Access23 Jan 2024
BJC Reports

Volume: 2, P: 1-7

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