The complex and diverse molecular architectures along with broad biological activities of ent-kauranoids natural products attract increasing interest from synthetic chemists. Herein, the authors report the enantioselective total syntheses of C-19 oxygenated enmein-type ent-kauranoids, including (–)-macrocalyxoformins A and B and (–)-ludongnin C.
- Zichen Cao
- Wenxuan Sun
- Chao Li