It is important to understand cellular uptake of nanoparticles, but the effects of cell cycle and autophagy are underexplored. Here, the authors construct a multi-functional, multi-dimensional platform, and use this to characterise the effects of cell cycle- and autophagy-associated cellular accumulation of clinically used lipid-based nanoparticles.
- Yisha Wang
- Gan Luo
- Meihua Sui