Nature Search

Sintilimab and anlotinib with gemcitabine plus cisplatin in advanced biliary tract cancer: SAGC a randomized phase 2 trial

Limited improvement of systemic therapy has been achieved in first line treatment for advanced Biliary tract cancer (BTC). In this randomized phase 2 trial on BTC, the combination of sintilimab, anlotinib, and gemcitabine/cisplatin demonstrated an improvement in progression - free survival (PFS) and objective response rate (ORR) while reducing the risk of disease progression compared to chemotherapy monotherapy.

Jingjing Li
Shurui Zhou
Jieer Ying
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-15
A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma

The MET receptor is frequently activated in cancer. Here, the authors show that in head and neck and lung squamous carcinoma, a polymorphic MET variant enhances binding to HER2, resulting in activation of HER2 signalling and progression of the cancers.

Li Ren Kong
Nur Afiqah Binte Mohamed Salleh
Boon Cher Goh
ResearchOpen Access25 Mar 2020
Nature Communications

Volume: 11, P: 1-14
Construction of a Shared Decision-Making Model Between Doctor and Patient in China Based on Selection Preferences

Yuwen Lyu
Junrong Liu
ResearchOpen Access17 Nov 2023
Humanities and Social Sciences Communications

Volume: 10, P: 1-7
Pathogenic variants in the Alport genes are prevalent in the Singapore multiethnic population with highest frequency in the Chinese

Tina Si Ting Lim
Chee Teck Koh
Yaochun Zhang
ResearchOpen Access05 Mar 2025
Scientific Reports

Volume: 15, P: 1-12
The blocking and transmission effects of lower level system in patent transaction - evidence from Chinese colleges and universities

Zhang Junrong
ResearchOpen Access07 May 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-8
Correction: Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation

Ying Jin
Hua Bao
Xinmin Yu
Amendments and Corrections12 Dec 2019
Oncogene

Volume: 39, P: 2027
Ultrafast laser state active controlling based on anisotropic quasi-1D material

Zixin Yang
Qiang Yu
Pu Zhou
ResearchOpen Access07 Apr 2024
Light: Science & Applications

Volume: 13, P: 1-10
Exploring potential molecular resistance and clonal evolution in advanced HER2-positive gastric cancer under trastuzumab therapy

Qi Xu
Xiaoqing Xu
Jieer Ying
ResearchOpen Access18 Apr 2023
Oncogenesis

Volume: 12, P: 1-11
16S rRNA gene sequencing reveals an altered composition of the gut microbiota in chickens infected with a nephropathogenic infectious bronchitis virus

Puzhi Xu
Yan Shi
Xiaoquan Guo
ResearchOpen Access26 Feb 2020
Scientific Reports

Volume: 10, P: 1-12
Repeated use of SSRIs potentially associated with an increase on serum CK and CK-MB in patients with major depressive disorder: a retrospective study

Shengwei Wu
Yufang Zhou
Lin Yu
ResearchOpen Access28 Jun 2021
Scientific Reports

Volume: 11, P: 1-8
Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation

Ying Jin
Hua Bao
Xinmin Yu
Research21 Nov 2019
Oncogene

Volume: 39, P: 1846-1859
Development of a novel individualized warfarin dose algorithm based on a population pharmacokinetic model with improved prediction accuracy for Chinese patients after heart valve replacement

Yu-bin Zhu
Xian-hua Hong
Jian-guo Sun
Research20 Feb 2017
Acta Pharmacologica Sinica

Volume: 38, P: 434-442

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Sintilimab and anlotinib with gemcitabine plus cisplatin in advanced biliary tract cancer: SAGC a randomized phase 2 trial

A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma

Construction of a Shared Decision-Making Model Between Doctor and Patient in China Based on Selection Preferences

Pathogenic variants in the Alport genes are prevalent in the Singapore multiethnic population with highest frequency in the Chinese

The blocking and transmission effects of lower level system in patent transaction - evidence from Chinese colleges and universities

Correction: Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation

Ultrafast laser state active controlling based on anisotropic quasi-1D material

Exploring potential molecular resistance and clonal evolution in advanced HER2-positive gastric cancer under trastuzumab therapy

16S rRNA gene sequencing reveals an altered composition of the gut microbiota in chickens infected with a nephropathogenic infectious bronchitis virus

Repeated use of SSRIs potentially associated with an increase on serum CK and CK-MB in patients with major depressive disorder: a retrospective study

Distinct co-acquired alterations and genomic evolution during TKI treatment in non-small-cell lung cancer patients with or without acquired T790M mutation

Development of a novel individualized warfarin dose algorithm based on a population pharmacokinetic model with improved prediction accuracy for Chinese patients after heart valve replacement

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