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Advanced filters: Author: Kayla Tyskiewicz Clear advanced filters

  • A cell-based phenotypic screen identifying inhibitors of Notch signaling led to the discovery of NVS-ZP7-4, which blocks the activity of the zinc transporter SLC39a7 (ZIP7) and induces cell death through an ER stress mechanism.

    • Erin Nolin
    • Sara Gans
    • Christy J. Fryer
    Research
    Nature Chemical Biology
    Volume: 15, P: 179-188