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Showing 1–5 of 5 results
Advanced filters: Author: Kenin Qian Clear advanced filters

  • PPM1D is a known mediator of p53 signalling, and has been linked to treatment resistance in glioma. In this work, the authors utilise genomics, proteomics, and mouse models to determine the role of PPM1D in the development of diffuse midline glioma.

    • Prasidda Khadka
    • Zachary J. Reitman
    • Pratiti Bandopadhayay
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-18

  • Pilocytic astrocytoma is a low-grade pediatric glioma, characterized by a single BRAF rearrangement. Here, Reitman and colleagues use single-cell RNA sequencing to reveal molecular hallmarks of the disease that might be targeted therapeutically.

    • Zachary J. Reitman
    • Brenton R. Paolella
    • Rameen Beroukhim
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-17

  • The authors present a protocol for genome-wide clustered regularly interspaced short palindromic repeat screening of three-dimensional neurospheres.

    • Tanaz Abid
    • Amy B. Goodale
    • David E. Root
    Protocols
    Nature Protocols
    Volume: 18, P: 2014-2031