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Showing 1–7 of 7 results

Advanced filters: Author: Konrad Aumann Clear advanced filters

Demethylating therapy increases anti-CD123 CAR T cell cytotoxicity against acute myeloid leukemia

The success of CAR-T cells for treating acute myeloid leukaemia (AML) is hampered by toxicity to normal cells and low CAR-T cell persistence. Here, the authors show that the demethylating compound 5′-Azacitdine increases anti-CD123 CAR-T cell cytotoxicity against AML.

Nadia El Khawanky
Amy Hughes
Robert Zeiser
ResearchOpen Access08 Nov 2021
Nature Communications

Volume: 12, P: 1-20
Oncogenic and microenvironmental signals drive cell type specific apoptosis resistance in juvenile myelomonocytic leukemia

Naile Koleci
Ying Wu
Miriam Erlacher
ResearchOpen Access08 Mar 2025
Cell Death & Disease

Volume: 16, P: 1-12
Azacitidine is effective for targeting leukemia-initiating cells in juvenile myelomonocytic leukemia

Christopher F. Krombholz
Lorena Gallego-Villar
Christian Flotho
Research24 Jan 2019
Leukemia

Volume: 33, P: 1805-1810
Correction to: Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection

Benedikt Dörflinger
Mohamed Tarek Badr
Georg Häcker
Amendments and CorrectionsOpen Access16 May 2022
Cell Death & Differentiation

Volume: 30, P: 854
BH3 mimetics and azacitidine show synergistic effects on juvenile myelomonocytic leukemia

Ying Wu
Patricia M. A. Zehnle
Miriam Erlacher
ResearchOpen Access09 Nov 2023
Leukemia

Volume: 38, P: 136-148
Mast cell deficiency prevents BCR::ABL1 induced splenomegaly and cytokine elevation in a CML mouse model

Melanie Langhammer
Julia Schöpf
Sebastian Halbach
ResearchOpen Access09 May 2023
Leukemia

Volume: 37, P: 1474-1484
Mitochondria supply sub-lethal signals for cytokine secretion and DNA-damage in H. pylori infection

Benedikt Dörflinger
Mohamed Tarek Badr
Georg Häcker
ResearchOpen Access03 May 2022
Cell Death & Differentiation

Volume: 29, P: 2218-2232