Nature Search

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Geospatial estimates of the prevalence of anemia in women of reproductive age across 82 low-income and middle-income countries reveals considerable heterogeneity and inequality at national and subnational levels, with few countries on track to meet the WHO Global Nutrition Targets by 2030.

Damaris Kinyoki
Aaron E. Osgood-Zimmerman
Simon I. Hay
ResearchOpen Access12 Oct 2021
Nature Medicine

Volume: 27, P: 1761-1782
Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

Systematic analysis from the Global Burden of Disease study reported that, despite global improvements from 1990 to 2021, dietary iron deficiency-associated disease burden remains high in women, children and residents in low socio-demographic index countries.

Sooji Lee
Yejun Son
Nicholas. J. Kassebaum
Research22 Apr 2025
Nature Medicine

Volume: 31, P: 1809-1829
Mapping inequalities in exclusive breastfeeding in low- and middle-income countries, 2000–2018

Bhattacharjee and Schaeffer et al. map exclusive breastfeeding (EBF) in 94 low- and middle-income countries (LMICs), finding increased EBF practice and reduced subnational variation across the majority of LMICs from 2000 to 2018. However, only six LMICs will meet WHO’s target of ≥70% EBF by 2030 nationally, and only three will achieve this in all districts.

Natalia V. Bhattacharjee
Lauren E. Schaeffer
Simon I. Hay
ResearchOpen Access03 Jun 2021
Nature Human Behaviour

Volume: 5, P: 1027-1045
Mapping routine measles vaccination in low- and middle-income countries

Although progress in the coverage of routine measles vaccination in children in low- and middle-income countries was made during 2000–2019, many countries remain far from the goal of 80% coverage in all districts by 2019.

Alyssa N. Sbarra
Sam Rolfe
Jonathan F. Mosser
ResearchOpen Access16 Dec 2020
Nature

Volume: 589, P: 415-419
Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

A high-resolution, global atlas of mortality of children under five years of age between 2000 and 2017 highlights subnational geographical inequalities in the distribution, rates and absolute counts of child deaths by age.

Roy Burstein
Nathaniel J. Henry
Simon I. Hay
ResearchOpen Access16 Oct 2019
Nature

Volume: 574, P: 353-358
Global estimates on the number of people blind or visually impaired by age-related macular degeneration: a meta-analysis from 2000 to 2020

João M. Furtado
Jost B. Jonas
Rupert R. A. Bourne
ResearchOpen Access04 Jul 2024
Eye

Volume: 38, P: 2070-2082
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Fine-scale geospatial mapping of overweight and wasting (two components of the double burden of malnutrition) in 105 LMICs shows that overweight has increased from 5.2% in 2000 to 6.0% in children under 5 in 2017. Although overall wasting decreased over the same period, most countries are not on track to meet the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025.

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
ResearchOpen Access20 Apr 2020
Nature Medicine

Volume: 26, P: 750-759
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes

Bhardwaj et al., have explored the proteomes of SARS-CoV and SARS-CoV-2, and have demonstrated the amyloid formation of viral proteins, in vitro, through diverse biophysical techniques.

Taniya Bhardwaj
Kundlik Gadhave
Rajanish Giri
ResearchOpen Access20 Feb 2023
Nature Communications

Volume: 14, P: 1-16
High failure rate of ChAdOx1-nCoV19 immunization against asymptomatic infection in healthcare workers during a Delta variant surge

The authors study a cohort of healthcare workers in India who received two doses of the ChAdOx-1-nCoV19 vaccine during the Delta wave. Using serological data, they infer that 25% of the cohort were infected within 60 days of vaccination, although there were no severe infections leading to hospitalisations.

Rajat Ujjainiya
Akansha Tyagi
Shantanu Sengupta
ResearchOpen Access01 Apr 2022
Nature Communications

Volume: 13, P: 1-6
The overlapping burden of the three leading causes of disability and death in sub-Saharan African children

In this disease mapping study, the authors estimate disability-adjusted life year rates for three of the major causes of mortality for children under five 43 countries in sub-Saharan Africa. They identify significant heterogeneity at the subnational level, highlighting the need for a targeted intervention approach.

Robert C. Reiner Jr.
Catherine A. Welgan
Simon I. Hay
ResearchOpen Access06 Dec 2022
Nature Communications

Volume: 13, P: 1-14
Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells

Kazumi Ebine
Krishan Kumar
Hidayatullah G. Munshi
ResearchOpen Access05 Sept 2018
Scientific Reports

Volume: 8, P: 1-11
Mycobacterium tuberculosis strain with deletions in menT3 and menT4 is attenuated and confers protection in mice and guinea pigs

Gosain et al.’s work aims to enhance understanding of the contribution of MenT3 and MenT4 toxins belonging to MenAT TA systems to the physiology and pathogenesis of Mycobacterium tuberculosis. The authors show that strains lacking these proteins is attenuated and confers protection in vivo.

Tannu Priya Gosain
Saurabh Chugh
Ramandeep Singh
ResearchOpen Access27 Jun 2024
Nature Communications

Volume: 15, P: 1-16
EZH2-H3K27me3 mediated KRT14 upregulation promotes TNBC peritoneal metastasis

Enhancer of zeste homolog 2 (EZH2) has been associated with poor prognosis in triple negative breast cancer (TNBC). Here, the authors suggest a potential role for trimethylation function of EZH2 in driving peritoneal metastasis in TNBC.

Ayushi Verma
Akhilesh Singh
Dipak Datta
ResearchOpen Access29 Nov 2022
Nature Communications

Volume: 13, P: 1-22
Mapping child growth failure across low- and middle-income countries

High-resolution subnational mapping of child growth failure indicators for 105 low- and middle-income countries between 2000 and 2017 shows that, despite considerable progress, substantial geographical inequalities still exist in some countries.

Damaris K. Kinyoki
Aaron E. Osgood-Zimmerman
Simon I. Hay
ResearchOpen Access08 Jan 2020
Nature

Volume: 577, P: 231-234
Global mortality of snakebite envenoming between 1990 and 2019

Snakebite envenoming is a leading cause of mortality among neglected tropical diseases. Here, the authors analyze a global data repository and estimate that snakebite envenoming caused over 63,000 deaths in 2019, primarily concentrated in South Asia and Sub-Saharan Africa.

Nicholas L. S. Roberts
Emily K. Johnson
Kanyin Liane Ong
ResearchOpen Access25 Oct 2022
Nature Communications

Volume: 13, P: 1-11
Mapping disparities in education across low- and middle-income countries

Analyses of the proportions of individuals who have completed key levels of schooling across all low- and middle-income countries from 2000 to 2017 reveal inequalities across countries as well as within populations.

Nicholas Graetz
Lauren Woyczynski
Simon I. Hay
ResearchOpen Access25 Dec 2019
Nature

Volume: 577, P: 235-238
An integrative TLBO-driven hybrid grey wolf optimizer for the efficient resolution of multi-dimensional, nonlinear engineering problems

Harleenpal Singh
Sobhit Saxena
Woong Cho
ResearchOpen Access02 Apr 2025
Scientific Reports

Volume: 15, P: 1-71
Functional combinatorial precision medicine for predicting and optimizing soft tissue sarcoma treatments

Sharon Pei Yi Chan
Masturah Bte Mohd Abdul Rashid
Edward Kai-Hua Chow
ResearchOpen Access22 Mar 2025
npj Precision Oncology

Volume: 9, P: 1-16
GLI2-dependent c-MYC upregulation mediates resistance of pancreatic cancer cells to the BET bromodomain inhibitor JQ1

Krishan Kumar
Sania S. Raza
Hidayatullah G. Munshi
ResearchOpen Access25 Mar 2015
Scientific Reports

Volume: 5, P: 1-9
Author Correction: Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
Amendments and CorrectionsOpen Access02 Jul 2020
Nature Medicine

Volume: 26, P: 1308
Chloroplasts evolved an additional layer of translational regulation based on non-AUG start codons for proteins with different turnover rates

Leelavathi Sadhu
Krishan Kumar
Vanga Siva Reddy
ResearchOpen Access17 Jan 2023
Scientific Reports

Volume: 13, P: 1-15
Analysis of glass fiber-reinforced composite leaf springs in a light commercial vehicle

Shivam Aggarwal
Krishan Kumar
M. L. Aggarwal
ResearchOpen Access29 Aug 2024
Scientific Reports

Volume: 14, P: 1-16
Global gene expression profiling under nitrogen stress identifies key genes involved in nitrogen stress adaptation in maize (Zea mays L.)

Prabha Singh
Krishan Kumar
Ishwar Singh
ResearchOpen Access10 Mar 2022
Scientific Reports

Volume: 12, P: 1-18
Ammonia is associated with liver-related complications and predicts mortality in acute-on-chronic liver failure patients

Kessarin Thanapirom
Sombat Treeprasertsuk
Shiv Kumar Sarin
ResearchOpen Access09 Mar 2024
Scientific Reports

Volume: 14, P: 1-8
Global estimates on the number of people blind or visually impaired by Uncorrected Refractive Error: a meta-analysis from 2000 to 2020

Julie-Anne Little
Nathan G. Congdon
Rupert Bourne
ResearchOpen Access04 Jul 2024
Eye

Volume: 38, P: 2083-2101
ROCK1/MLC2 inhibition induces decay of viral mRNA in BPXV infected cells

Ram Kumar
Yogesh Chander
Naveen Kumar
ResearchOpen Access24 Oct 2022
Scientific Reports

Volume: 12, P: 1-14
A randomized trial of once daily versus twice daily dosing of oral iron in CKD

Vivek Sood
Kajal Kamboj
Vivekanand Jha
ResearchOpen Access04 Jan 2023
Scientific Reports

Volume: 13, P: 1-9
A comprehensive DNA barcoding of Indian freshwater fishes of the Indus River system, Beas

Sonakshi Modeel
Ram Krishan Negi
Tarana Negi
ResearchOpen Access02 Feb 2024
Scientific Reports

Volume: 14, P: 1-13
Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020

Konrad Pesudovs
Van Charles Lansingh
Jaimie D. Steinmetz
ResearchOpen Access09 Mar 2024
Eye

Volume: 38, P: 2156-2172
Global estimates on the number of people blind or visually impaired by glaucoma: A meta-analysis from 2000 to 2020

Rupert R. A. Bourne
Jost B. Jonas
Jaimie D. Steinmetz
ResearchOpen Access02 Apr 2024
Eye

Volume: 38, P: 2036-2046
Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus

Deepika Chaudhary
Avantika Singh
Ramandeep Singh
ResearchOpen Access13 Aug 2022
Scientific Reports

Volume: 12, P: 1-16
Evaluation of micronutrient profile of North Indian children with cystic fibrosis: a case–control study

Krishan Yadav
Meenu Singh
Anil Kumar Bhalla
Research06 Apr 2014
Pediatric Research

Volume: 75, P: 762-766
Kelvin-Helmholtz instability in a compressible dust fluid flow

Krishan Kumar
P. Bandyopadhyay
A. Sen
ResearchOpen Access09 Mar 2023
Scientific Reports

Volume: 13, P: 1-12
Inhibition of p21 activates Akt kinase to trigger ROS-induced autophagy and impacts on tumor growth rate

Mayank Maheshwari
Nisha Yadav
Jayanta Sarkar
ResearchOpen Access15 Dec 2022
Cell Death & Disease

Volume: 13, P: 1-13
Global estimates on the number of people blind or visually impaired by diabetic retinopathy: a meta-analysis from 2000 to 2020

Katie Curran
Tunde Peto
Peng Zheng
ResearchOpen Access27 Jun 2024
Eye

Volume: 38, P: 2047-2057
Transcriptome sequencing of a thalloid bryophyte; Dumortiera hirsuta (Sw) Nees: assembly, annotation and marker discovery

Harpal Singh
Krishan Mohan Rai
Pradhyumna Kumar Singh
ResearchOpen Access20 Oct 2015
Scientific Reports

Volume: 5, P: 1-10
Publisher Correction: Global estimates on the number of people blind or visually impaired by cataract: a meta-analysis from 2000 to 2020

Konrad Pesudovs
Van Charles Lansingh
Jaimie D. Steinmetz
Amendments and CorrectionsOpen Access16 Jul 2024
Eye

Volume: 38, P: 2229-2231
Characterization of recombinant β subunit of human MUC4 mucin (rMUC4β)

Prakash G. Kshirsagar
Mansi Gulati
Maneesh Jain
ResearchOpen Access09 Dec 2021
Scientific Reports

Volume: 11, P: 1-13
Epigenetic regulation of gene expression improves Fusarium head blight resistance in durum wheat

Jitendra Kumar
Krishan M. Rai
Shahryar F. Kianian
ResearchOpen Access19 Oct 2020
Scientific Reports

Volume: 10, P: 1-15
Defining the Environmental Adaptations of Genus Devosia: Insights into its Expansive Short Peptide Transport System and Positively Selected Genes

Chandni Talwar
Shekhar Nagar
Ram Krishan Negi
ResearchOpen Access24 Jan 2020
Scientific Reports

Volume: 10, P: 1-18
Profiling invasive Plasmodium falciparum merozoites using an integrated omics approach

Krishan Kumar
Prakash Srinivasan
David L. Narum
ResearchOpen Access07 Dec 2017
Scientific Reports

Volume: 7, P: 1-17
Genome-wide DNA Methylation and RNAseq Analyses Identify Aberrant Signalling Pathways in Focal Cortical Dysplasia (FCD) Type II

Aparna Banerjee Dixit
Devina Sharma
P. Sarat Chandra
ResearchOpen Access19 Dec 2018
Scientific Reports

Volume: 8, P: 1-12
Genome-wide identification of multifunctional laccase gene family in cotton (Gossypium spp.); expression and biochemical analysis during fiber development

Vimal Kumar Balasubramanian
Krishan Mohan Rai
Venugopal Mendu
ResearchOpen Access29 Sept 2016
Scientific Reports

Volume: 6, P: 1-16
Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia

Kazumi Ebine
Christina R. Chow
Hidayatullah G. Munshi
ResearchOpen Access01 Jul 2016
Scientific Reports

Volume: 6, P: 1-10
CXCR4 intracellular protein promotes drug resistance and tumorigenic potential by inversely regulating the expression of Death Receptor 5

Mushtaq A. Nengroo
Shrankhla Maheshwari
Dipak Datta
ResearchOpen Access08 May 2021
Cell Death & Disease

Volume: 12, P: 1-19

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