Nature Search

The Somatic Mosaicism across Human Tissues Network

The Somatic Mosaicism across Human Tissues Network aims to create a reference catalogue of somatic mosaicism across different tissues and cells within individuals.

Tim H. H. Coorens
Ji Won Oh
Yuqing Wang
Reviews02 Jul 2025
Nature

Volume: 643, P: 47-59
Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures

Glioma tumours are known to be heterogenous in mutation and gene expression patterns, but sampling limitations can lead to inaccurate detection of evolutionary events. Here, the authors carry out multi-omics analysis of multi-regional biopsies from 68 patients and show differential mutations in non-enhancing regions.

Leland S. Hu
Fulvio D’Angelo
Nhan L. Tran
ResearchOpen Access28 Sept 2023
Nature Communications

Volume: 14, P: 1-20
Publisher Correction: Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults

Mark J. Mulligan
Kirsten E. Lyke
Kathrin U. Jansen
Amendments and Corrections19 Jan 2021
Nature

Volume: 590, P: E26
Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults

In a dose-escalation study of the COVID-19 RNA vaccine BNT162b1 in 45 healthy adults, RBD-binding IgG concentrations and SARS-CoV-2 neutralizing titres in sera increased with dose level and after a second vaccine dose.

Mark J. Mulligan
Kirsten E. Lyke
Kathrin U. Jansen
Research12 Aug 2020
Nature

Volume: 586, P: 589-593
BNT162b vaccines protect rhesus macaques from SARS-CoV-2

BNT162b1 and BNT162b2 are two candidate mRNA vaccines against COVID-19 that elicit high virus-entry inhibition titres in mice, elicit high virus-neutralizing titres in rhesus macaques and protect macaques from SARS-CoV-2 challenge.

Annette B. Vogel
Isis Kanevsky
Ugur Sahin
Research01 Feb 2021
Nature

Volume: 592, P: 283-289
Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

Despite major drug discovery efforts, the therapeutic options for glioblastoma (GBM) remain inadequate. Here they analyze patient-derived xenograft model of GBM to quantitatively map distribution and cellular response to the EGFR inhibitor erlotinib, and report heterogeneous erlotinib delivery to intracranial tumors to be inadequate to inhibit EGFR signaling.

Elizabeth C. Randall
Kristina B. Emdal
Nathalie Y. R. Agar
ResearchOpen Access21 Nov 2018
Nature Communications

Volume: 9, P: 1-13
Molecular omics resources should require sex annotation: a call for action

The most commonly used omics databases are a compilation of results from primarily male-only and sex-agnostic studies. The pervasive use of these databases critically hinders progress toward fully accounting for the biology of sex differences.

Kamila M. Bond
Margaret M. McCarthy
Kristin R. Swanson
Comments & Opinion07 Jun 2021
Nature Methods

Volume: 18, P: 585-588
Biologically informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post treatment glioblastoma

Hairong Wang
Michael G. Argenziano
Jing Li
ResearchOpen Access19 Oct 2024
npj Digital Medicine

Volume: 7, P: 1-14
Uncertainty quantification in the radiogenomics modeling of EGFR amplification in glioblastoma

Leland S. Hu
Lujia Wang
Jing Li
ResearchOpen Access16 Feb 2021
Scientific Reports

Volume: 11, P: 1-14
Preclinical characterization of the Omicron XBB.1.5-adapted BNT162b2 COVID-19 vaccine

Kayvon Modjarrad
Ye Che
Kena A. Swanson
ResearchOpen Access20 Nov 2024
npj Vaccines

Volume: 9, P: 1-13
Integration of machine learning and mechanistic models accurately predicts variation in cell density of glioblastoma using multiparametric MRI

Nathan Gaw
Andrea Hawkins-Daarud
Jing Li
ResearchOpen Access11 Jul 2019
Scientific Reports

Volume: 9, P: 1-9
Comprehensive molecular characterization of human colon and rectal cancer

The Cancer Genome Atlas consortium reports on their genome-wide characterization of somatic alterations in colorectal cancer; in addition to revealing a remarkably consistent pattern of genomic alteration, with 24 genes being significantly mutated, the study identifies new targets for therapeutic intervention and suggests an important role for MYC-directed transcriptional activation and repression.

Donna M. Muzny
Matthew N. Bainbridge
Elizabeth Thomson.
ResearchOpen Access18 Jul 2012
Nature

Volume: 487, P: 330-337
Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

With the continued interest in the role of the gut microbiota in health, attention has now turned to how to harness the microbiota for the benefit of the host. This Consensus Statement outlines the definition and scope of the term 'prebiotic' as determined by an expert panel convened by the International Scientific Association for Probiotics and Prebiotics in December 2016.

Glenn R. Gibson
Robert Hutkins
Gregor Reid
ReviewsOpen Access14 Jun 2017
Nature Reviews Gastroenterology & Hepatology

Volume: 14, P: 491-502
Shape matters: morphological metrics of glioblastoma imaging abnormalities as biomarkers of prognosis

Lee Curtin
Paula Whitmire
Kristin R. Swanson
ResearchOpen Access01 Dec 2021
Scientific Reports

Volume: 11, P: 1-11
The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics

Gut microbiota can be manipulated to benefit host health, including the use of probiotics, prebiotics and synbiotics. This Consensus Statement outlines the definition and scope of the term ‘synbiotics’ as determined by an expert panel convened by the International Scientific Association for Probiotics and Prebiotics in May 2019.

Kelly S. Swanson
Glenn R. Gibson
Mary Ellen Sanders
ReviewsOpen Access21 Aug 2020
Nature Reviews Gastroenterology & Hepatology

Volume: 17, P: 687-701
The effect of SARS-CoV-2 D614G mutation on BNT162b2 vaccine-elicited neutralization

Jing Zou
Xuping Xie
Pei-Yong Shi
ResearchOpen Access25 Mar 2021
npj Vaccines

Volume: 6, P: 1-4
Author Correction: Integrative analysis of DNA, macroscopic remains and stable isotopes of dog coprolites to reconstruct community diet

Kelsey E. Witt
Karthik Yarlagadda
Ripan S. Malhi
Amendments and CorrectionsOpen Access26 May 2021
Scientific Reports

Volume: 11, P: 1
Integrative analysis of DNA, macroscopic remains and stable isotopes of dog coprolites to reconstruct community diet

Kelsey E. Witt
Karthik Yarlagadda
Ripan S. Malhi
ResearchOpen Access04 Feb 2021
Scientific Reports

Volume: 11, P: 1-16
Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy

Peder R Braadland
Guro Giskeødegård
May-Britt Tessem
ResearchOpen Access03 Oct 2017
British Journal of Cancer

Volume: 117, P: 1656-1664
Long-Term Exposure to Oral Methylphenidate or dl-Amphetamine Mixture in Peri-Adolescent Rhesus Monkeys: Effects on Physiology, Behavior, and Dopamine System Development

Paul L Soto
Kristin M Wilcox
Michael R Weed
Research18 Jul 2012
Neuropsychopharmacology

Volume: 37, P: 2566-2579
A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms

Sook-Lei Liew
Bethany P. Lo
Chunshui Yu
ResearchOpen Access16 Jun 2022
Scientific Data

Volume: 9, P: 1-12

Search

The Somatic Mosaicism across Human Tissues Network

Integrated molecular and multiparametric MRI mapping of high-grade glioma identifies regional biologic signatures

Publisher Correction: Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults

Phase I/II study of COVID-19 RNA vaccine BNT162b1 in adults

BNT162b vaccines protect rhesus macaques from SARS-CoV-2

Integrated mapping of pharmacokinetics and pharmacodynamics in a patient-derived xenograft model of glioblastoma

Molecular omics resources should require sex annotation: a call for action

Biologically informed deep neural networks provide quantitative assessment of intratumoral heterogeneity in post treatment glioblastoma

Uncertainty quantification in the radiogenomics modeling of EGFR amplification in glioblastoma

Preclinical characterization of the Omicron XBB.1.5-adapted BNT162b2 COVID-19 vaccine

Integration of machine learning and mechanistic models accurately predicts variation in cell density of glioblastoma using multiparametric MRI

Comprehensive molecular characterization of human colon and rectal cancer

Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics

Shape matters: morphological metrics of glioblastoma imaging abnormalities as biomarkers of prognosis

The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics

The effect of SARS-CoV-2 D614G mutation on BNT162b2 vaccine-elicited neutralization

Author Correction: Integrative analysis of DNA, macroscopic remains and stable isotopes of dog coprolites to reconstruct community diet

Integrative analysis of DNA, macroscopic remains and stable isotopes of dog coprolites to reconstruct community diet

Ex vivo metabolic fingerprinting identifies biomarkers predictive of prostate cancer recurrence following radical prostatectomy

Long-Term Exposure to Oral Methylphenidate or dl-Amphetamine Mixture in Peri-Adolescent Rhesus Monkeys: Effects on Physiology, Behavior, and Dopamine System Development

A large, curated, open-source stroke neuroimaging dataset to improve lesion segmentation algorithms

Search

Quick links

Search

Filter By:

Search

Quick links