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Showing 1–50 of 118 results

Advanced filters: Author: Kyung Yeon Han Clear advanced filters

HDL-bound S1P affects the subventricular niche and early neuropathological features of Alzheimer’s disease

The blood ApoM-S1P complex regulates vascular functions, but its role in neurogenic niches remains unclear. Here, the authors show that the blood ApoM-S1P complex preserves V-SVZ homeostasis and protects against early features of Alzheimer’s disease.

Byung Jo Choi
Ju Yeon Hong
Hee Kyung Jin
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-22
Publisher Correction: Analysis of the serial circulating tumor cell count during neoadjuvant chemotherapy in breast cancer patients

Sungchan Gwark
Jisun Kim
Sei Hyun Ahn
Amendments and CorrectionsOpen Access11 Mar 2021
Scientific Reports

Volume: 11, P: 1
Anti-proteolytic regulation of KRAS by USP9X/NDRG3 in KRAS-driven cancer development

The regulation of KRAS oncoprotein stability remains to be completely determined. Here the authors identify that USP9X-mediated deubiquitination of KRAS protein is dependent on scaffolding protein NDRG3, suggesting KRAS-NDRG3 interaction as a targetable vulnerability in KRAS-driven cancers.

Han Koo
Kyung Chan Park
Dong Chul Lee
ResearchOpen Access16 Jan 2025
Nature Communications

Volume: 16, P: 1-17
Author Correction: Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons

Kyung Ah Han
Taek-Han Yoon
Jaewon Ko
Amendments and CorrectionsOpen Access23 Jul 2024
Nature Communications

Volume: 15, P: 1
Author Correction: Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons

Kyung Ah Han
Taek-Han Yoon
Jaewon Ko
Amendments and CorrectionsOpen Access07 Mar 2024
Nature Communications

Volume: 15, P: 1
Author Correction: Early Detection and Serial Monitoring of Anthracycline-Induced Cardiotoxicity Using T1-mapping Cardiac Magnetic Resonance Imaging: An Animal Study

Yoo Jin Hong
Heae Surng Park
Byoung Wook Choi
Amendments and CorrectionsOpen Access09 Jun 2022
Scientific Reports

Volume: 12, P: 1
Author Correction: A roadmap for the commercialization of perovskite light emitters

Tae-Hee Han
Kyung Yeon Jang
Tae-Woo Lee
Amendments and Corrections12 Sept 2022
Nature Reviews Materials

Volume: 7, P: 833
Deep learning-based quantitative analysis of glomerular morphology in IgA nephropathy whole slide images and its prognostic implications

Seung Yeon Cho
Yisak Kim
Young-Gon Kim
ResearchOpen Access02 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
Clusterin inhibits lipopolysaccharide induced liver injury

Hye-Young Seo
Ji Yeon Park
Byoung Kuk Jang
ResearchOpen Access18 Feb 2025
Scientific Reports

Volume: 15, P: 1-11
Taurine ameliorates hyperglycemia and dyslipidemia by reducing insulin resistance and leptin level in Otsuka Long-Evans Tokushima fatty (OLETF) rats with long-term diabetes

Kyoung Soo Kim
Da Hee Oh
In-Kyung Jeong
ResearchOpen Access21 Sept 2012
Experimental & Molecular Medicine

Volume: 44, P: 665-673
Author Correction: A cross-sectional study of ophthalmologic examination findings in 5385 Koreans presenting with intermittent exotropia

Dae Hee Kim
Jae Ho Jung
Soon Young Cho
Amendments and CorrectionsOpen Access14 Feb 2023
Scientific Reports

Volume: 13, P: 1
Mapping the human genetic architecture of COVID-19

A global network of researchers was formed to investigate the role of human genetics in SARS-CoV-2 infection and COVID-19 severity; this paper reports 13 genome-wide significant loci and potentially actionable mechanisms in response to infection.

Mari E. K. Niemi
Juha Karjalainen
Chloe Donohue
ResearchOpen Access08 Jul 2021
Nature

Volume: 600, P: 472-477
Specification of neural circuit architecture shaped by context-dependent patterned LAR-RPTP microexons

LAR-RPTPs are presynaptic cell-adhesion proteins that regulate the synaptic properties. Here, LAR-RPTP microexon expression is profiled in region-, cell-type- and circuit-specific contexts and its physiological significance in encoding synaptic architecture is demonstrated.

Kyung Ah Han
Taek-Han Yoon
Jaewon Ko
ResearchOpen Access22 Feb 2024
Nature Communications

Volume: 15, P: 1-21
A cross-sectional study of ophthalmologic examination findings in 5385 Koreans presenting with intermittent exotropia

Dae Hee Kim
Jae Ho Jung
Soon Young Cho
ResearchOpen Access24 Jan 2023
Scientific Reports

Volume: 13, P: 1-8
Conductive-bridge interlayer contacts for two-dimensional optoelectronic devices

A gold-embedded oxide interlayer can be used to create metal–interlayer–semiconductor contacts for two-dimensional materials that exhibit low series resistance and Fermi level depinning.

Jisu Jang
Jung Pyo Hong
Do Kyung Hwang
Research05 Feb 2025
Nature Electronics

Volume: 8, P: 298-308
Chemotherapy induces dynamic immune responses in breast cancers that impact treatment outcome

Neoadjuvant chemotherapy is a therapeutic option for the treatment of breast cancer. Here, the authors characterize changes in the gene expression profiles and immune microenvironment in serial breast cancer biopsies taken before, during and after neoadjuvant chemotherapy.

Yeon Hee Park
Samir Lal
Zhengyan Kan
ResearchOpen Access02 Dec 2020
Nature Communications

Volume: 11, P: 1-14
Neuroprotective effects of roasted licorice, not raw form, on neuronal injury in gerbil hippocampus after transient forebrain ischemia

In-koo Hwang
Soon-sung Lim
Moo-ho Won
Research01 Aug 2006
Acta Pharmacologica Sinica

Volume: 27, P: 959-965
Single-cell RNA sequencing of peripheral blood links cell-type-specific regulation of splicing to autoimmune and inflammatory diseases

This analysis of single-cell RNA sequencing data from peripheral blood mononuclear cells for 474 individuals of diverse Asian ancestries in the Asian Immune Diversity Atlas links cell-type-specific splicing variation with autoimmune and inflammatory disease risk.

Chi Tian
Yuntian Zhang
Boxiang Liu
ResearchOpen Access03 Dec 2024
Nature Genetics

Volume: 56, P: 2739-2752
Immunotherapy targeting plasma ASM is protective in a mouse model of Alzheimer’s disease

Acid sphingomyelinase (ASM) is a sphingolipid metabolizing enzyme that catalyzes the hydrolysis of sphingomyelin to ceramide, and previous work has shown it is upregulated in models of Alzheimer’s disease. Here the authors demonstrate in a mouse model of Alzheimer’s disease that antibody-based immunotherapy targeting plasma ASM resulted in attenuated neuropathological features by suppressing pathogenic Th17 cells.

Byung Jo Choi
Min Hee Park
Jae-sung Bae
ResearchOpen Access24 Mar 2023
Nature Communications

Volume: 14, P: 1-17
O-GlcNAcylation of NONO regulates paraspeckle component assembly and contributes to colon cancer cell proliferation

Yeolhoe Kim
Kyung-Tae Lee
Won Ho Yang
ResearchOpen Access13 May 2025
Cell Death Discovery

Volume: 11, P: 1-12
Association between root canals and gingival sulci microbiota in secondary and persistent endodontic infections

Dong Hyun Park
Euon Jung Tak
Seung Hyun Han
ResearchOpen Access02 Apr 2025
Scientific Reports

Volume: 15, P: 1-11
Single-nucleotide variant calling in single-cell sequencing data with Monopogen

Monopogen identifies single-nucleotide variants in single-cell sequencing data.

Jinzhuang Dou
Yukun Tan
Ken Chen
ResearchOpen Access17 Aug 2023
Nature Biotechnology

Volume: 42, P: 803-812
Author Correction: Battery-free, wireless soft sensors for continuous multi-site measurements of pressure and temperature from patients at risk for pressure injuries

Yong Suk Oh
Jae-Hwan Kim
John A. Rogers
Amendments and CorrectionsOpen Access18 Nov 2021
Nature Communications

Volume: 12, P: 1
Systematic functional analysis of kinases in the fungal pathogen Cryptococcus neoformans

Cryptococcus neoformans is the leading cause of death by fungal meningoencephalitis. Here, the authors study the roles played by 129 putative kinases in the growth and virulence of C. neoformans, identifying potential targets for development of anticryptococcal drugs.

Kyung-Tae Lee
Yee-Seul So
Yong-Sun Bahn
ResearchOpen Access28 Sept 2016
Nature Communications

Volume: 7, P: 1-16
Neonatal and developmental outcomes of very preterm twins according to the chorionicity and weight discordance

Soo Yeon Lim
Seung Han Shin
Jong Kwan Jun
ResearchOpen Access26 Apr 2023
Scientific Reports

Volume: 13, P: 1-9
Soybean isoflavones alter parvalbumin in hippocampus of mid-aged normal female, ovariectomized female, and normal male rats

In Koo Hwang
Yoon-bok Lee
Moo Ho Won
Research01 Jan 2006
Acta Pharmacologica Sinica

Volume: 27, P: 59-65
Ellagic acid improves benign prostate hyperplasia by regulating androgen signaling and STAT3

Woo Yong Park
Gahee Song
Jae-Young Um
ResearchOpen Access17 Jun 2022
Cell Death & Disease

Volume: 13, P: 1-11
Clonal hematopoiesis is associated with risk of severe Covid-19

Clonal haematopoiesis (CH) has been associated with altered inflammatory profiles and increased risk of cardiovascular and malignant diseases. Here, the authors analyze patient data from two different cohorts and show that CH is associated with severe infections and severe Covid19.

Kelly L. Bolton
Youngil Koh
Ahmet Zehir
ResearchOpen Access13 Oct 2021
Nature Communications

Volume: 12, P: 1-8
Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

Genetic heterogeneity in breast cancer has been demonstrated at a single-cell resolution with high levels of genome coverage. Here, the authors perform transcriptome analysis of 515 single cells from 11 patients and define core gene expression signatures for subtype-specific single breast cancer cells and tumour-infiltrating immune cells.

Woosung Chung
Hye Hyeon Eum
Woong-Yang Park
ResearchOpen Access05 May 2017
Nature Communications

Volume: 8, P: 1-12
Author Correction: Proteogenomic landscape of human pancreatic ductal adenocarcinoma in an Asian population reveals tumor cell-enriched and immune-rich subtypes

Do Young Hyeon
Dowoon Nam
Sang-Won Lee
Amendments and Corrections19 May 2023
Nature Cancer

Volume: 4, P: 774
CHIP controls necroptosis through ubiquitylation- and lysosome-dependent degradation of RIPK3

Receptor-interacting protein kinase 3 (RIPK3) is a key regulator of necroptosis. Seo et al. show that the E3 ligase CHIP mediates ubiquitylation and lysosomal degradation of RIPK3, thus regulating both necrosome formation and necroptosis.

Jinho Seo
Eun-Woo Lee
Jaewhan Song
Research22 Feb 2016
Nature Cell Biology

Volume: 18, P: 291-302
Genome-wide association study identifies GYS2 as a novel genetic factor for polycystic ovary syndrome through obesity-related condition

Joo-Yeon Hwang
Eun-Ju Lee
Jong-Young Lee
Research06 Sept 2012
Journal of Human Genetics

Volume: 57, P: 660-664
Valley-centre tandem perovskite light-emitting diodes

A hybrid valley-centre tandem optical structure that combines perovskites and organic light-emitting diodes is demonstrated to obtain an efficient emitting device, showing the commercial potential of perovskite displays.

Hyeon-Dong Lee
Seung-Je Woo
Tae-Woo Lee
Research16 Jan 2024
Nature Nanotechnology

Volume: 19, P: 624-631
Battery-free, wireless soft sensors for continuous multi-site measurements of pressure and temperature from patients at risk for pressure injuries

Uninterrupted monitoring of pressure and temperature at skin interfaces can help to minimize the potential for pressure injuries in hospitalized or bedridden patients. Here, the authors introduce a soft, skin-mountable sensor that can continuously provide readings via antennas mounted under bedding, and demonstrate the functionality and robustness of the devices on patients.

Yong Suk Oh
Jae-Hwan Kim
John A. Rogers
ResearchOpen Access24 Aug 2021
Nature Communications

Volume: 12, P: 1-16
Monocrotaline-induced pulmonary hypertension correlates with upregulation of connective tissue growth factor expression in the lung

Young-Sam Lee
Jonghoe Byun
Duk-Kyung Kim
ResearchOpen Access01 Feb 2005
Experimental & Molecular Medicine

Volume: 37, P: 27-35
Women Who Sleep More Have Reduced Risk of Peptic Ulcer Disease; Korean National Health and Nutrition Examination Survey (2008–2009)

Sun-Hye Ko
Myong Ki Baeg
Kyung-Do Han
ResearchOpen Access10 Nov 2016
Scientific Reports

Volume: 6, P: 1-6
Blood pressure and mortality after percutaneous coronary intervention: a population-based cohort study

Chung-woo Lee
Joo Kyung Lee
Joo-Hyun Park
ResearchOpen Access17 Feb 2022
Scientific Reports

Volume: 12, P: 1-9
A propensity score-adjusted analysis of efficacy of high-flow nasal oxygen during awake tracheal intubation

Hye Jin Kim
Min-Soo Kim
Hyun Joo Kim
ResearchOpen Access04 Jul 2022
Scientific Reports

Volume: 12, P: 1-7
Association between bronchopulmonary dysplasia and early respiratory morbidity in children with respiratory distress syndrome: a case–control study using nationwide data

Jeong Eun Shin
Haerin Jang
Kyung Won Kim
ResearchOpen Access09 May 2022
Scientific Reports

Volume: 12, P: 1-8
Development and validation of an interpretable model for predicting sepsis mortality across care settings

Young Seok Lee
Seungbong Han
Hyung Koo Kang
ResearchOpen Access13 Jun 2024
Scientific Reports

Volume: 14, P: 1-11
Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation

AMPK activation has been suggested as treatment for obesity and its complications. Here the authors show that the ubiquitin ligase MKRN1 binds to AMPK and mediates its ubiquitination and degradation. Loss of MKRN1 leads to AMPK activation, increased glucose consumption and decreased lipid accumulation.

Min-Sik Lee
Hyun-Ji Han
Jaewhan Song
ResearchOpen Access24 Aug 2018
Nature Communications

Volume: 9, P: 1-14
Metabolic Syndrome and Incidence of Laryngeal Cancer: A Nationwide Cohort Study

Sang-Yeon Kim
Kyung-do Han
Young-Hoon Joo
ResearchOpen Access24 Jan 2019
Scientific Reports

Volume: 9, P: 1-6
VIM-AS1, which is regulated by CpG methylation, cooperates with IGF2BP1 to inhibit tumor aggressiveness via EPHA3 degradation in hepatocellular carcinoma

Su-hyang Han
Je Yeong Ko
Jong Hoon Park
ResearchOpen Access02 Dec 2024
Experimental & Molecular Medicine

Volume: 56, P: 2617-2630
Overexpression and unique rearrangement of VH2 transcripts in immunoglobulin variable heavy chain genes in ankylosing spondylitis patients

Yeon Joo Kim
Nayoung Kim
Chang-Hoon Nam
ResearchOpen Access22 Feb 2010
Experimental & Molecular Medicine

Volume: 42, P: 319-326
p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis

Soluble misfolded proteins that fail to be degraded by the ubiquitin proteasome system (UPS) are redirected to autophagy via specific adaptors, such as p62. Here the authors show that p62 recognises N-degrons in these proteins, acting as a N-recognin from the proteolytic N-end rule pathway, and targets these cargos to autophagosomal degradation.

Hyunjoo Cha-Molstad
Ji Eun Yu
Bo Yeon Kim
ResearchOpen Access24 Jul 2017
Nature Communications

Volume: 8, P: 1-17
Bacterial entombment by intratubular mineralization following orthograde mineral trioxide aggregate obturation: a scanning electron microscopy study

Jun Sang Yoo
Seok-Woo Chang
Kee-Yeon Kum
ResearchOpen Access11 Jul 2014
International Journal of Oral Science

Volume: 6, P: 227-232
Selective crack suppression during deformation in metal films on polymer substrates using electron beam irradiation

Cracking in thin films is usually associated with failure. Here, the authors use an electron beam to selectively irradiate a copper thin film on a polymer substrate and introduce designed cracks under tension to make a strain responsive organic light-emitting device (OLED).

So-Yeon Lee
Kyung Ryoul Park
In-Suk Choi
ResearchOpen Access01 Oct 2019
Nature Communications

Volume: 10, P: 1-8
A large-scale genome-wide association study of Asian populations uncovers genetic factors influencing eight quantitative traits

Hyung-Lae Kim and colleagues report a genome-wide association study of quantitative traits of biomedical importance in Koreans. Although some loci were previously detected in European populations, others are new.

Yoon Shin Cho
Min Jin Go
Hyung-Lae Kim
Research26 Apr 2009
Nature Genetics

Volume: 41, P: 527-534
Author Correction: Keratin-mediated hair growth and its underlying biological mechanism

Seong Yeong An
Hyo-Sung Kim
Yu-Shik Hwang
Amendments and CorrectionsOpen Access22 Dec 2022
Communications Biology

Volume: 5, P: 1
Publisher Correction: Keratin-mediated hair growth and its underlying biological mechanism

Seong Yeong An
Hyo-Sung Kim
Yu-Shik Hwang
Amendments and CorrectionsOpen Access22 Dec 2022
Communications Biology

Volume: 5, P: 1

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