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Showing 1–50 of 91 results

Advanced filters: Author: Larry Miller Clear advanced filters

Structure-based design of a lysozyme with altered catalytic activity

Ryota Kuroki
Larry H. Weaver
Brian W. Matthews
Research01 Nov 1995
Nature Structural Biology

Volume: 2, P: 1007-1011
Climate change in the circum-North Atlantic region during the last deglaciation

Jonathan T. Overpeck
Larry C. Peterson
David Rind
Research13 Apr 1989
Nature

Volume: 338, P: 553-557
Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis

Larry G. Johnson
John C. Olsen
Richard C. Boucher
Research01 Sept 1992
Nature Genetics

Volume: 2, P: 21-25
Specific purine N⁷-nitrogens are critical for high affinity binding by the trp repressor

Stephen A. Smith
Sharanabasava B. Rajur
Larry W. McLaughlin
Research01 Jan 1994
Nature Structural Biology

Volume: 1, P: 18-22
A plant cyclin-dependent kinase inhibitor gene

Hong Wang
Larry C. Fowke
William L. Crosby
Research03 Apr 1997
Nature

Volume: 386, P: 451-452
One neuron, many units?

Larry Cohen
Jian-young Wu
News & Views12 Jul 1990
Nature

Volume: 346, P: 108-109
Author Correction: Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes

Sheri Skerget
Daniel Penaherrera
Jonathan J. Keats
Amendments and CorrectionsOpen Access09 Jun 2025
Nature Genetics

P: 1
An unusual transposon with long terminal inverted repeats in the sea urchin Strongylocentrotus purpuratus

Dan Liebermann
Barbara Hoffman-Liebermann
Larry Kedes
Research24 Nov 1983
Nature

Volume: 306, P: 342-347
Clinical Utility of Presacral Neurectomy as an Adjunct to Conservative Endometriosis Surgery: Systematic Review and Meta-Analysis of Controlled Studies

Larry E. Miller
Ruemon Bhattacharyya
Valerie M. Miller
ResearchOpen Access23 Apr 2020
Scientific Reports

Volume: 10, P: 1-8
Unitary anion currents through phospholemman channel molecules

J. Randall Moorman
Stephen J. Ackerman
Larry R. Jones
Research26 Oct 1995
Nature

Volume: 377, P: 737-740
Human xeroderma pigmentosum group D gene encodes a DMA helicase

Patrick Sung
Véronique Bailly
Satya Prakash
Research28 Oct 1993
Nature

Volume: 365, P: 852-855
Induction of c-fos during myelomonocytic differentiation and macrophage proliferation

Rolf Müller
Tom Curran
Larry Guilbert
Research11 Apr 1985
Nature

Volume: 314, P: 546-548
In vivo and in vitro effect of α-amanitin on preimplantation mouse embryo RNA polymerase

CAROL M. WARNER
LARRY R. VERSTEEGH
Research19 Apr 1974
Nature

Volume: 248, P: 678-680
Design and application of synthetic 17B-HSD13 substrates reveals preserved catalytic activity of protective human variants

Several 17B-HSD13 variants have been identified as protective against NASH/MASH. However the protein’s endogenous function is unknown. Here authors describe sulfonamide-based inhibitors and synthetic substrates, then apply to multiple cellular systems revealing that the most prevalent IsoD variant maintains NAD-dependent catalytic activity.

Michelle R. Garnsey
Yang Wang
Michelle F. Clasquin
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-10
The natural ovalbumin gene contains seven intervening sequences

Achilles Dugaiczyk
Savio L. C. Woo
Bert W. O'Malley
Research27 Jul 1978
Nature

Volume: 274, P: 328-333
From aptamer-based biomarker discovery to diagnostic and clinical applications: an aptamer-based, streamlined multiplex proteomic assay

Stephan Kraemer
Jonathon Vaught
Glenn Sanders
ResearchOpen Access09 Jul 2010
Nature Precedings

P: 1
Mapping class I gene sequences in the major histocompatibility complex

Larry R. Pease
Stanley G. Nathenson
Leslie A. Leinwand
Research22 Jul 1982
Nature

Volume: 298, P: 382-385
Neurotensin blocks certain amphetamine-induced behaviours

Gregory N. Ervin
Larry S. Birkemo
Arthur J. Prange Jr
Research07 May 1981
Nature

Volume: 291, P: 73-76
Unlocking biomarker discovery: Large scale application of aptamer proteomic technology for early detection of lung cancer

Rachel Ostroff
William Bigbee
Edward Brody
ResearchOpen Access15 Jun 2010
Nature Precedings

P: 1
Small molecule APOL1 inhibitors as a precision medicine approach for APOL1-mediated kidney disease

Apolipoprotein L1 genetic variants contribute to a subtype of proteinuric kidney disease referred to as APOL1-mediated kidney disease (AMKD). Here the authors report the discovery and characterization of potent and selective APOL1 ion channel inhibitors for the potential treatment of AMKD.

Brandon Zimmerman
Leslie A. Dakin
Mark E. Bunnage
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-13
Aptamer-based multiplexed proteomic technology for biomarker discovery

Larry Gold
Deborah Ayers
Dom Zichi
ResearchOpen Access14 Jun 2010
Nature Precedings

P: 1
Ribozymes in gene therapy

James D. Thompson
Dennis Macejak
Dan T. Stinchcomb
Advertorial01 Mar 1995
Nature Medicine

Volume: 1, P: 277-278
Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans

Barbara R. Grubb
Raymond J. Pickles
Richard C. Boucher
Research27 Oct 1994
Nature

Volume: 371, P: 802-806
Photoreduction of methyl viologen in aqueous neutral solution without additives

Thomas W. Ebbesen
Gerrit Levey
Larry K. Patterson
Research05 Aug 1982
Nature

Volume: 298, P: 545-548
An inositol tetrakisphosphate-containing phospholipid in activated neutrophils

Alexis E. Traynor-Kaplan
Anna L. Harris
Larry A. Sklar
Research01 Jul 1988
Nature

Volume: 334, P: 353-356
Clinical assessment of a hand-held automated keratometer in cataract surgery

Martin Leyland
Larry Benjamin
Research01 Nov 1997
Eye

Volume: 11, P: 854-857
The Effect of Route of Delivery on Neonatal Natural Killer Cytotoxicity and Antibody-Dependent Cellular Cytotoxicity to Herpes Simplex Virus-Infected Cells

Johnnie P Frazier
Steve Kohl
Lian-Sim Loo
Research01 Jul 1982
Pediatric Research

Volume: 16, P: 558-560
Are tick populations really less variable and should they be?

Larry R Hilburn
Paul W Sattler
Research01 Aug 1986
Heredity

Volume: 57, P: 113-117
Photo-accelerated fast charging of lithium-ion batteries

Here the authors show that illumination of a lithium manganese oxide cathode can induce efficient charge-separation and electron transfer processes, thus giving rise to a new type of fast lithium-ion battery charging.

Anna Lee
Márton Vörös
Christopher S. Johnson
ResearchOpen Access30 Oct 2019
Nature Communications

Volume: 10, P: 1-7
Correction: Corrigendum: A nanostructured cathode architecture for low charge overpotential in lithium-oxygen batteries

Jun Lu
Yu Lei
Khalil Amine
Amendments and Corrections19 Feb 2014
Nature Communications

Volume: 5, P: 1
Decreased gastrointestinal toxicity associated with a novel capecitabine schedule (7 days on and 7 days off): a systematic review

Karen A Cadoo
Devika Gajria
Tiffany A Traina
ResearchOpen Access30 Mar 2016
npj Breast Cancer

Volume: 2, P: 1-5
Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington’s disease

Zinc finger protein transcription factors are developed for the selective silencing of the mutant huntingtin gene in human neurons in vitro and multiple animal models of Huntington’s disease in vivo while preserving expression of the wild-type allele.

Bryan Zeitler
Steven Froelich
H Steve Zhang
Research01 Jul 2019
Nature Medicine

Volume: 25, P: 1131-1142
Divergent medial amygdala projections regulate approach–avoidance conflict behavior

Miller et al. show that subpopulations of D1 receptor-expressing neurons in the medial amygdala modulate approach–avoidance responses to threats through inhibitory and excitatory projections to the extended amygdala and hypothalamus, respectively.

Samara M. Miller
Daniele Marcotulli
Larry S. Zweifel
Research25 Feb 2019
Nature Neuroscience

Volume: 22, P: 565-575
Decreased Response of Human Milk Leukocytes to Chemoattractant Peptides

Larry W Thorpe
H Elizabeth Rudloff
Armond S Goldman
Research01 Apr 1986
Pediatric Research

Volume: 20, P: 373-377
Epigenome-wide meta-analysis of PTSD across 10 military and civilian cohorts identifies methylation changes in AHRR

PTSD has been associated with DNA methylation of specific loci in the genome, but studies have been limited by small sample sizes. Here, the authors perform a meta-analysis of DNA methylation data from 10 different cohorts and identify CpGs in AHRR that are associated with PTSD.

Alicia K. Smith
Andrew Ratanatharathorn
Caroline M. Nievergelt
ResearchOpen Access24 Nov 2020
Nature Communications

Volume: 11, P: 1-9
Prevalence and determinants of shared decision-making for PSA testing in the United States

Naeem Bhojani
Larry E. Miller
Ben H. Chew
Research26 Apr 2024
Prostate Cancer and Prostatic Diseases

Volume: 28, P: 400-404
Comprehensive molecular profiling of multiple myeloma identifies refined copy number and expression subtypes

Longitudinal genomic and transcriptomic profiling of 1,143 patients with multiple myeloma by the Relating Clinical Outcomes in Multiple Myeloma to Personal Assessment of Genetic Profile study yields an improved copy number and gene expression subtype scheme, most notably a high-risk proliferative subtype associated with complete loss of RB1 or MAX.

Sheri Skerget
Daniel Penaherrera
Jonathan J. Keats
ResearchOpen Access19 Aug 2024
Nature Genetics

Volume: 56, P: 1878-1889
A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies

STAARpipeline is a comprehensive framework for flexible and scalable rare-variant association analysis using whole-genome sequencing data and annotation information.

Zilin Li
Xihao Li
Xihong Lin
Research27 Oct 2022
Nature Methods

Volume: 19, P: 1599-1611
Lightning Pose: improved animal pose estimation via semi-supervised learning, Bayesian ensembling and cloud-native open-source tools

Lightning Pose is an efficient pose estimation approach that requires few labeled training data owing to its semi-supervised learning strategy and ensembling.

Dan Biderman
Matthew R. Whiteway
Liam Paninski
Research25 Jun 2024
Nature Methods

Volume: 21, P: 1316-1328
Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

Sandip Ray
Markus Britschgi
Tony Wyss-Coray
Research14 Oct 2007
Nature Medicine

Volume: 13, P: 1359-1362
A nanostructured cathode architecture for low charge overpotential in lithium-oxygen batteries

Lithium-oxygen batteries can deliver high-energy densities, but their performance suffers from large charge-discharge overpotential. Lu et al.design a cathode by integrating electrode coating and electrocatalyst in a nanostructured architecture, whereby the overpotential is reduced to 0.2 V.

Jun Lu
Yu Lei
Khalil Amine
Research29 Aug 2013
Nature Communications

Volume: 4, P: 1-10
Effect of the size-selective silver clusters on lithium peroxide morphology in lithium–oxygen batteries

Insights into active sites on cathode surfaces are important in developing lithium–oxygen batteries. Here, Lu et al.present a cathode architecture deposited with precisely controlled small metal clusters, and report a cluster size-dependence of the battery discharge product morphology.

Jun Lu
Lei Cheng
Larry A. Curtiss
Research12 Sept 2014
Nature Communications

Volume: 5, P: 1-8
Clonal haematopoiesis and risk of chronic liver disease

A study shows that clonal haematopoiesis of indeterminate potential is associated with an increased risk of chronic liver disease specifically through the promotion of liver inflammation and injury.

Waihay J. Wong
Connor Emdin
Pradeep Natarajan
Research12 Apr 2023
Nature

Volume: 616, P: 747-754
Human whole-exome genotype data for Alzheimer’s disease

The heterogeneity of whole-exome sequencing (WES) data generation methods presents a challenge to joint analysis. Here, the authors present a bioinformatics strategy to generate high-quality data from processing diversely generated WES samples, as applied in the Alzheimer’s Disease Sequencing Project.

Yuk Yee Leung
Adam C. Naj
Li-San Wang
ResearchOpen Access23 Jan 2024
Nature Communications

Volume: 15, P: 1-15
Chromosome Xq23 is associated with lower atherogenic lipid concentrations and favorable cardiometabolic indices

The influence of X chromosome genetic variation on blood lipids and coronary heart disease (CHD) is not well understood. Here, the authors analyse X chromosome sequencing data across 65,322 multi-ancestry individuals, identifying associations of the Xq23 locus with lipid changes and reduced risk of CHD and diabetes mellitus.

Pradeep Natarajan
Akhil Pampana
Gina M. Peloso
ResearchOpen Access12 Apr 2021
Nature Communications

Volume: 12, P: 1-14
In vivo protein interaction network analysis reveals porin-localized antibiotic inactivation in Acinetobacter baumannii strain AB5075

The bacterial pathogen Acinetobacter baumannii has evolved resistance to many antibiotics, including carbapenems. Here, Wu et al. show that the carbapenemase Oxa-23 interacts with the outer membrane porin CarO in an A. baumanniiisolate, indicative of porin-localised antibiotic inactivation.

Xia Wu
Juan D. Chavez
James E. Bruce
ResearchOpen Access11 Nov 2016
Nature Communications

Volume: 7, P: 1-14
Burning lithium in CS₂ for high-performing compact Li₂S–graphene nanocapsules for Li–S batteries

Facile and scalable fabrication of high-performing sulfur cathodes is challenging in the commercialization of Li–S batteries. The authors report a strategy of simply burning Li foils in a CS₂ vapour for the cathode design, which shows promising battery performance.

Guoqiang Tan
Rui Xu
Khalil Amine
Research12 Jun 2017
Nature Energy

Volume: 2, P: 1-10
A framework for human microbiome research

The Human Microbiome Project Consortium has established a population-scale framework to study a variety of microbial communities that exist throughout the human body, enabling the generation of a range of quality-controlled data as well as community resources.

Barbara A. Methé
Karen E. Nelson
Owen White
ResearchOpen Access13 Jun 2012
Nature

Volume: 486, P: 215-221
Enhanced partner preference in a promiscuous species by manipulating the expression of a single gene

Miranda M. Lim
Zuoxin Wang
Larry J. Young
Research17 Jun 2004
Nature

Volume: 429, P: 754-757
Vasoprotection as neuroprotection for the optic nerve

Alon Harris
Thomas A Ciulla
Bruce Martin
Research01 May 2000
Eye

Volume: 14, P: 473-475

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