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Showing 1–50 of 76 results

Advanced filters: Author: Li-Li Xu Clear advanced filters

Erratum: Crossover of the three-dimensional topological insulator Bi₂Se₃ to the two-dimensional limit

Yi Zhang
Ke He
Qi-Kun Xue
Amendments and Corrections01 Sept 2010
Nature Physics

Volume: 6, P: 712
Endothelial cells-derived SEMA3G suppresses glioblastoma stem cells by inducing c-Myc degradation

Peng-Xiang Min
Li-Li Feng
Feng Han
ResearchOpen Access18 Jun 2025
Cell Death & Differentiation

P: 1-15
Arylcarboxylation of unactivated alkenes with CO₂ via visible-light photoredox catalysis

Despite the importance of polycyclic carboxylic acids and derivatives in various fields, general methods for the arylcarboxylation of alkenes with CO₂ remain elusive. Here, the authors transform unactivated alkenes into high value-added polycyclic carboxylic acids and derivatives via visible-light photoredox-catalysis, using CO₂ as the one-carbon feedstock.

Wei Zhang
Zhen Chen
Da-Gang Yu
ResearchOpen Access14 Jun 2023
Nature Communications

Volume: 14, P: 1-10
Visible-light photocatalytic di- and hydro-carboxylation of unactivated alkenes with CO₂

The activation of CO₂ for catalytic carboxylation of alkenes is mainly limited to two-electron processes. Now, a visible-light photocatalytic single-electron transfer reduction of CO₂ is reported leading to the key intermediate CO₂^•−, which allows carboxylation of unactivated aliphatic alkenes.

Lei Song
Wei Wang
Da-Gang Yu
Research15 Sept 2022
Nature Catalysis

Volume: 5, P: 832-838
Reductive dearomative arylcarboxylation of indoles with CO₂ via visible-light photoredox catalysis

Catalytic reductive coupling of two electrophiles and one C = C bond is usually performed by two electron transfer metal catalysis. Herein, the authors show a visible light photoredox-catalyzed successive single electron transfer leading to dearomative arylcarboxylation of indoles with CO₂ and generating indoline-3-carboxylic acids.

Wen-Jun Zhou
Zhe-Hao Wang
Da-Gang Yu
ResearchOpen Access29 Jun 2020
Nature Communications

Volume: 11, P: 1-9
Visible-light-driven synthesis of N-heteroaromatic carboxylic acids by thiolate-catalysed carboxylation of C(sp²)–H bonds using CO₂

The catalytic carboxylation of C(sp²)–H bonds using CO₂ is an efficient strategy to produce carboxylic acids; however, the carboxylation of azines is a challenge. Now, a visible-light-driven, thiolate-catalysed method for the carboxylation of azine C(sp²)–H bonds using CO₂ is reported, enabling the synthesis of N-heteroaromatic carboxylic acids with excellent regiocontrol.

Yuan-Xu Jiang
Li-Li Liao
Da-Gang Yu
Research11 Jan 2024
Nature Synthesis

Volume: 3, P: 394-405
Ultrasound imaging of the perithyroid fascial space: a comparative analysis with anatomical correlations

Ying Wei
Zhen-long Zhao
Ming-an Yu
ResearchOpen Access06 Feb 2025
Scientific Reports

Volume: 15, P: 1-8
Etiological and epidemiological features of acute respiratory infections in China

China operates a national surveillance program for acute respiratory infections and sampled over 200,000 patients between 2009–2019. Here, the authors present results from this program and describe patterns by age, pathogen type, presence of pneumonia, and season.

Zhong-Jie Li
Hai-Yang Zhang
Jun Wang
ResearchOpen Access18 Aug 2021
Nature Communications

Volume: 12, P: 1-11
A tumour-selective cascade activatable self-detained system for drug delivery and cancer imaging

The activation of drugs within cellular systems may provide targeted therapies for cancer. Here, the authors make a drug delivery system that is activated within the cell and exploits XIAP expression to cleave a linker region, resulting in the self-assembly of the system and drug release within cancer cells.

Hong-Wei An
Li-Li Li
Yuliang Zhao
ResearchOpen Access24 Oct 2019
Nature Communications

Volume: 10, P: 1-15
Danthron activates AMP-activated protein kinase and regulates lipid and glucose metabolism in vitro

Rong Zhou
Ling Wang
Xu Shen
Research17 Jun 2013
Acta Pharmacologica Sinica

Volume: 34, P: 1061-1069
Outcomes of allogeneic hematopoietic stem cell transplantation versus intensive chemotherapy in patients with myeloid sarcoma: a nationwide representative multicenter study

Jie Sun
Yi-Cheng Zhang
Xiao-Hui Zhang
Research02 Dec 2024
Bone Marrow Transplantation

Volume: 60, P: 319-325
Marine natural product des-O-methyllasiodiplodin effectively lowers the blood glucose level in db/db mice via ameliorating inflammation

Rong Zhou
Zhong-hui Lin
Xu Shen
Research15 Jul 2013
Acta Pharmacologica Sinica

Volume: 34, P: 1325-1336
TSG attenuated NAFLD and facilitated weight loss in HFD-fed mice via activating the RUNX1/FGF21 signaling axis

Zhen-lin Huang
Shao-bo Zhang
Li-li Ji
Research30 Apr 2025
Acta Pharmacologica Sinica

P: 1-11
Complexin 2 contributes to the protective effect of NAD⁺ on neuronal survival following neonatal hypoxia-ischemia

Xiao-wen Xu
Xiu-wen Zhou
Hong Ni
Research17 Apr 2025
Acta Pharmacologica Sinica

P: 1-13
Co-option of a non-retroviral endogenous viral element in planthoppers

Non-retroviral endogenous viral elements are widely dispersed in eukaryotic genomes, but their functions remain largely unknown. Here, Huang et al show that one such element in planthoppers has been co-opted and contributes to insect fitness..

Hai-Jian Huang
Yi-Yuan Li
Jun-Min Li
ResearchOpen Access09 Nov 2023
Nature Communications

Volume: 14, P: 1-19
Ultra-high dose rate radiotherapy overcomes radioresistance in head and neck squamous cell carcinoma

Hong-Shuai Li
Ruo Tang
Xing-Chen Peng
ResearchOpen Access03 Mar 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-17
C333H, a novel PPARα/γ dual agonist, has beneficial effects on insulin resistance and lipid metabolism

Cheng Xu
Li-li Wang
Song Li
Research01 Feb 2006
Acta Pharmacologica Sinica

Volume: 27, P: 223-228
Identification of Known and Novel PTCH Mutations in Both Syndromic and Non‐syndromic Keratocystic Odontogenic Tumors

Shuang Pan
Li‐li Xu
Tie‐jun Li
Research01 Mar 2009
International Journal of Oral Science

Volume: 1, P: 34-38
A bioactivated in vivo assembly nanotechnology fabricated NIR probe for small pancreatic tumor intraoperative imaging

Fluorescence probes for detecting tumours during surgery can suffer from poor accumulation and short imaging windows. Here, the author develop fluorescence probes with multiple motifs that permit enhanced circulation times, tumour targeting and use the probes to image pancreatic cancer in mice

Han Ren
Xiang-Zhong Zeng
Li-Li Li
ResearchOpen Access20 Jan 2022
Nature Communications

Volume: 13, P: 1-13
Publisher Correction: Intramolecular chaperone-mediated secretion of an Rhs effector toxin by a type VI secretion system

Tong-Tong Pei
Hao Li
Tao G. Dong
Amendments and CorrectionsOpen Access06 May 2020
Nature Communications

Volume: 11, P: 1
Autophagy of OTUD5 destabilizes GPX4 to confer ferroptosis-dependent kidney injury

Understanding the role of GPX4 in cell ferroptosis at the interface of the inner cortex and medulla is crucial in the context of renal injury. Here, the authors demonstrate that the OTUD5 interaction with GPX4 is key in resisting ischemia/reperfusion-induced ferroptosis in renal cells, offering a new strategy for treating acute kidney injury.

Li-Kai Chu
Xu Cao
Jun Liu
ResearchOpen Access18 Dec 2023
Nature Communications

Volume: 14, P: 1-17
Antisense oligonucleotides-induced local blockade of T-bet expression leads to airway inflammation in rats

Gang Wang
Chun-tao Liu
Feng-min Luo
Research01 May 2006
Acta Pharmacologica Sinica

Volume: 27, P: 561-567
Derivatives of (phenylsulfonamido-methyl)nicotine and (phenylsulfonamido-methyl)thiazole as novel 11β-hydroxysteroid dehydrogenase type 1 inhibitors: synthesis and biological activities in vitro

Xu Zhang
Yang Zhou
Jian-hua Shen
Research24 Aug 2009
Acta Pharmacologica Sinica

Volume: 30, P: 1344-1350
Crossover of the three-dimensional topological insulator Bi₂Se₃ to the two-dimensional limit

The gapless surface states of topological insulators could enable quantitatively different types of electronic device. A study of the topological insulating Bi₂Se₃ thin films finds that a gap in these states opens up in films below a certain thickness. This in turn suggests that in thicker films, gapless states exist on both upper and lower surfaces.

Yi Zhang
Ke He
Qi-Kun Xue
Research13 Jun 2010
Nature Physics

Volume: 6, P: 584-588
Intramolecular chaperone-mediated secretion of an Rhs effector toxin by a type VI secretion system

Bacterial Rhs proteins with toxic domains are often secreted by type VI secretion systems. Here, the authors show that one of these proteins self-cleaves into three fragments, with the Rhs core and the N-terminal ___domain facilitating secretion and function of the C-terminal toxic ___domain.

Tong-Tong Pei
Hao Li
Tao G. Dong
ResearchOpen Access20 Apr 2020
Nature Communications

Volume: 11, P: 1-13
Retraction Note: MicroRNA-454 regulates stromal cell derived factor-1 in the control of the growth of pancreatic ductal adenocarcinoma

Yue Fan
Li-Li Xu
Ding-Fang Cai
Amendments and CorrectionsOpen Access06 Dec 2023
Scientific Reports

Volume: 13, P: 1
Design, synthesis and antitumor evaluation of a new series of N-substituted-thiourea derivatives

Jian Li
Jin-zhi Tan
Hua-liang Jiang
Research01 Sept 2006
Acta Pharmacologica Sinica

Volume: 27, P: 1259-1271
Neural mechanisms underlying strain preference behaviour and plasticity in mice

Kai-zhen Peng
Li-li Tan
Xiao-min Zhang
ResearchOpen Access24 Feb 2025
Scientific Reports

Volume: 15, P: 1-20
CDK4/6 inhibition triggers ICAM1-driven immune response and sensitizes LKB1 mutant lung cancer to immunotherapy

LKB1 mutations have been associated with primary resistance to immune checkpoint inhibitors in patients with lung cancer. Here the authors show that Lkb1-deficient lung tumors are characterized by defective trafficking and adhesion of T cells and that, by upregulating ICAM1 expression, CDK4/6 inhibitors sensitize LKB1 mutant lung cancer to anti-PD1 blockade.

Xue Bai
Ze-Qin Guo
Zhong-Yi Dong
ResearchOpen Access04 Mar 2023
Nature Communications

Volume: 14, P: 1-18
Enzymatic activity characterization of SARS coronavirus 3C-like protease by fluorescence resonance energy transfer technique

Shuai Chen
Li-li Chen
Hua-liang Jiang
Research01 Jan 2005
Acta Pharmacologica Sinica

Volume: 26, P: 99-106
Decreasing prevalence and time trend of gastroschisis in 14 cities of Liaoning Province: 2006–2015

Na Li
Yan-Ling Chen
Yan-Hong Huang
ResearchOpen Access14 Sept 2016
Scientific Reports

Volume: 6, P: 1-7
Effect of supersaturation on hillock of directional Growth of KDP crystals

Fa-Fu Liu
Guang-Wei Yu
Xun Sun
ResearchOpen Access03 Nov 2014
Scientific Reports

Volume: 4, P: 1-5
NLRP3-dependent microglial training impaired the clearance of amyloid-beta and aggravated the cognitive decline in Alzheimer’s disease

Xiao-fei He
Jing-hui Xu
Xi-quan Hu
ResearchOpen Access13 Oct 2020
Cell Death & Disease

Volume: 11, P: 1-11
Activating transcription factor 6 protects insulin receptor from ER stress-stimulated desensitization via p42/44 ERK pathway

Xuan Tang
Hong Shen
Xu Shen
Research15 Aug 2011
Acta Pharmacologica Sinica

Volume: 32, P: 1138-1147
Role of fundoplication in treatment of patients with symptoms of hiatal hernia

Zhi-tong Li
Feng Ji
Zhong-gao Wang
ResearchOpen Access29 Aug 2019
Scientific Reports

Volume: 9, P: 1-8
Comorbidity burden of patients with Parkinson’s disease and Parkinsonism between 2003 and 2012: A multicentre, nationwide, retrospective study in China

Xin Wang
Fan Zeng
Yan-Jiang Wang
ResearchOpen Access10 May 2017
Scientific Reports

Volume: 7, P: 1-6
RETRACTED ARTICLE: MicroRNA-454 regulates stromal cell derived factor-1 in the control of the growth of pancreatic ductal adenocarcinoma

Yue Fan
Li-Li Xu
Ding-Fang Cai
ResearchOpen Access15 Mar 2016
Scientific Reports

Volume: 6, P: 1-10
A nomogram for predicting T315I-free survival in chronic phase chronic myeloid leukemia patients: a multicenter retrospective study

Shi-wei Hu
Xiu-di Yang
Jian Huang
ResearchOpen Access18 Feb 2025
Scientific Reports

Volume: 15, P: 1-12
A novel hepatovirus identified in wild woodchuck Marmota himalayana

Jie-mei Yu
Li-li Li
Zhao-Jun Duan
ResearchOpen Access29 Feb 2016
Scientific Reports

Volume: 6, P: 1-11
Salivary proteins potentially derived from horizontal gene transfer are critical for salivary sheath formation and other feeding processes

An evolutional and functional study on bug saliva suggests that horizontally transferred genes provide a selective advantage to recipient insects by enhancing their feeding abilities.

Hai-Jian Huang
Li-Li Li
Chuan-Xi Zhang
ResearchOpen Access02 Mar 2024
Communications Biology

Volume: 7, P: 1-12
Acid-sensing ion channel 1a promotes alcohol-associated liver disease in mice via regulating endoplasmic reticulum autophagy

Yue-qin Zhu
Li-li Wang
Yan Huang
Research26 Nov 2024
Acta Pharmacologica Sinica

Volume: 46, P: 989-1001
The effect of inhibition of endoplasmic reticulum stress on lipolysis in white adipose tissue in a rat model of chronic kidney disease

Yan Zhu
Yu-ling Chen
Qiu-gen Zhou
Research20 Jan 2014
Acta Pharmacologica Sinica

Volume: 35, P: 356-362
L655,240, acting as a competitive BACE1 inhibitor, efficiently decreases β-amyloid peptide production in HEK293-APPswe cells

Qin Lu
Wu-yan Chen
Xu Shen
Research30 Jul 2012
Acta Pharmacologica Sinica

Volume: 33, P: 1459-1468
BNIP3-mediated mitophagy attenuates hypoxic–ischemic brain damage in neonatal rats by inhibiting ferroptosis through P62–KEAP1–NRF2 pathway activation to maintain iron and redox homeostasis

Xin-xin Wang
Mei Li
Hong Ni
Research23 Aug 2024
Acta Pharmacologica Sinica

Volume: 46, P: 33-51
Crosstalk between FTH1 and PYCR1 dysregulates proline metabolism and mediates cell growth in KRAS-mutant pancreatic cancer cells

Ji Min Park
Yen-Hao Su
Ching-Feng Chiu
ResearchOpen Access18 Sept 2024
Experimental & Molecular Medicine

Volume: 56, P: 2065-2081
Novel selective cannabinoid CB₁ receptor antagonist MJ08 with potent in vivo bioactivity and inverse agonistic effects

Wei Chen
Cheng Xu
Song Li
Research15 Aug 2011
Acta Pharmacologica Sinica

Volume: 32, P: 1148-1158
Depleting profibrotic macrophages using bioactivated in vivo assembly peptides ameliorates kidney fibrosis

Qing Ouyang
Chao Wang
Xiangmei Chen
Research13 Jun 2024
Cellular & Molecular Immunology

Volume: 21, P: 826-841
Transcriptome analysis provides insights into xylogenesis formation in Moso bamboo (Phyllostachys edulis) shoot

Hui Zhang
Ye-qing Ying
Ai-min Wu
ResearchOpen Access02 Mar 2018
Scientific Reports

Volume: 8, P: 1-16
Design, synthesis, antitumor evaluations and molecular modeling studies of novel 3,5-substituted indolin-2-one derivatives

Hai-hong Li
Xiu-hua Zhang
Hua-liang Jiang
Research01 Jan 2007
Acta Pharmacologica Sinica

Volume: 28, P: 140-152
Suppression of human lung cancer cell proliferation and metastasis in vitro by the transducer of ErbB-2.1 (TOB1)

Yang Jiao
Ke-kang Sun
Sai-jun Fan
Research12 Dec 2011
Acta Pharmacologica Sinica

Volume: 33, P: 250-260

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