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Acta Pharmacologica Sinica (18)
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Showing 1–50 of 72 results

Advanced filters: Author: Li-Ping Yang Clear advanced filters

Etiological and epidemiological features of acute respiratory infections in China

China operates a national surveillance program for acute respiratory infections and sampled over 200,000 patients between 2009–2019. Here, the authors present results from this program and describe patterns by age, pathogen type, presence of pneumonia, and season.

Zhong-Jie Li
Hai-Yang Zhang
Jun Wang
ResearchOpen Access18 Aug 2021
Nature Communications

Volume: 12, P: 1-11
Etiological, epidemiological, and clinical features of acute diarrhea in China

Diarrhoea is a major cause of morbidity and mortality in China. Here, the authors present results from a large sentinel surveillance scheme from 217 hospitals in all 31 provinces in mainland China, including ~150,000 patients with acute diarrhoea and covering years 2009-2018.

Li-Ping Wang
Shi-Xia Zhou
Jun Wang
ResearchOpen Access29 Apr 2021
Nature Communications

Volume: 12, P: 1-12
Tunable multi-electron redox polyoxometalates for decoupled water splitting driven by sunlight

Designing efficient redox mediators for solar-to-fuel conversion is a challenge, requiring multi-electron transfer, suitable redox potential, and stable pH buffering. Here, the authors report polyoxometalate-based mediators with defect engineering, enabling reliable solar-to-fuel conversion.

Li-Ping Cui
Shu Zhang
Jia-Jia Chen
ResearchOpen Access17 Apr 2025
Nature Communications

Volume: 16, P: 1-12
Theoretical characterization of mesoscopic structure of PBT propellant based on liquid film thickness

Ye-wei Shen
Mao-fa Yang
Xing-liang Wu
ResearchOpen Access15 Apr 2025
Scientific Reports

Volume: 15, P: 1-9
Changes in notifiable infectious disease incidence in China during the COVID-19 pandemic

Non-pharmaceutical interventions implemented to mitigate COVID-19 transmission are likely to have impacted spread of other infectious diseases. Here, the authors investigate changes in the incidence of 31 notifiable infectious diseases using surveillance data from China.

Meng-Jie Geng
Hai-Yang Zhang
Wei Liu
ResearchOpen Access26 Nov 2021
Nature Communications

Volume: 12, P: 1-11
Application of cardiovascular virtual endoscopy: a pilot study on roaming path planning for diagnosis of congenital heart diseases in children

Li-Ping Yao
Ju Mei
Kun Sun
ResearchOpen Access23 Jan 2018
Scientific Reports

Volume: 8, P: 1-7
Granzyme K⁺CD8⁺ T cells interact with fibroblasts to promote neutrophilic inflammation in nasal polyps

Chronic rhinosinusitis with nasal polyps generally has a type 2 inflammatory eosinophilic profile but can have a treatment resistant neutrophilic phenotype. Here the authors characterise nasal polyps using single cell sequencing and spatial transcriptomics and show granzyme K⁺CD8⁺ T cells associated with neutrophilic inflammation which promote release of neutrophilic chemoattractants from fibroblasts.

Cui-Lian Guo
Chong-Shu Wang
Zheng Liu
ResearchOpen Access29 Nov 2024
Nature Communications

Volume: 15, P: 1-22
Author Correction: Stabilizing indium sulfide for CO₂ electroreduction to formate at high rate by zinc incorporation

Li-Ping Chi
Zhuang-Zhuang Niu
Min-Rui Gao
Amendments and CorrectionsOpen Access15 Oct 2021
Nature Communications

Volume: 12, P: 1
In situ ammonium formation mediates efficient hydrogen production from natural seawater splitting

Efficient catalysts for seawater electrolysis are crucial for sustainable hydrogen production but struggle with slow kinetics and low durability. Here, the authors report a molybdenum nitride catalyst that in situ generates ammonium groups, enhancing both performance and stability in natural seawater.

Xiao-Long Zhang
Peng-Cheng Yu
Min-Rui Gao
ResearchOpen Access01 Nov 2024
Nature Communications

Volume: 15, P: 1-11
Lichenicolins A and B, New Bisnaphthopyrones from an Unidentified Lichenicolous Fungus, Strain LL-RB0668

Haiyin He
Ramunas Bigelis
Maya P Singh
Research01 Nov 2005
The Journal of Antibiotics

Volume: 58, P: 731-736
Isothiafludine, a novel non-nucleoside compound, inhibits hepatitis B virus replication through blocking pregenomic RNA encapsidation

Li Yang
Li-ping Shi
Jian-ping Zuo
Research03 Feb 2014
Acta Pharmacologica Sinica

Volume: 35, P: 410-418
Design, synthesis, antitumor evaluations and molecular modeling studies of novel 3,5-substituted indolin-2-one derivatives

Hai-hong Li
Xiu-hua Zhang
Hua-liang Jiang
Research01 Jan 2007
Acta Pharmacologica Sinica

Volume: 28, P: 140-152
Assessing changes in brain structure in new-onset children with acute lymphoblastic leukemia

Shu Su
Hua-qiong Qiu
Li-Ping Lin
Research20 Oct 2024
Pediatric Research

P: 1-7
Initial Upper Palaeolithic material culture by 45,000 years ago at Shiyu in northern China

The authors report an Initial Upper Palaeolithic archaeological assemblage from China dating to 45,000 years ago that includes blade technology, tanged and hafted projectile points, long-distance obsidian transfer and the use of a perforated graphite disc.

Shi-Xia Yang
Jia-Fu Zhang
Michael Petraglia
Research18 Jan 2024
Nature Ecology & Evolution

Volume: 8, P: 552-563
Stabilizing indium sulfide for CO₂ electroreduction to formate at high rate by zinc incorporation

Developing durable catalysts for carbon dioxide reduction to formate at commercial-scale current densities is challenging. This work reports that indium sulfide stabilized through zinc incorporation can produce formate efficiently and quickly at high current densities over long timescales.

Li-Ping Chi
Zhuang-Zhuang Niu
Min-Rui Gao
ResearchOpen Access05 Oct 2021
Nature Communications

Volume: 12, P: 1-9
Involvement of transcription factor activator protein-2α in doxazosin-induced HeLa cell apoptosis

Lu Gan
Dong-xing Zhu
Jian Zhang
Research01 Apr 2008
Acta Pharmacologica Sinica

Volume: 29, P: 465-472
Coherent control of single spins in silicon carbide at room temperature

Defects in silicon carbide have recently been proposed as bright single-photon sources. It is now shown that they can be used as sources of single electron spins having long coherence times at room temperature.

Matthias Widmann
Sang-Yun Lee
Jörg Wrachtrup
Research01 Dec 2014
Nature Materials

Volume: 14, P: 164-168
Bioactivity, pharmacokinetics, and immunogenicity assays in preclinical and clinical trials for recombinant human endostatin

Bi Hu
Hao-wen Zhu
Gen-xing Xu
Research01 Nov 2008
Acta Pharmacologica Sinica

Volume: 29, P: 1357-1369
Examining the impact of the packaging design of nearly expired food on consumer purchase intentions

Bilu Chen
Wen Hua
Shan Wu
ResearchOpen Access19 Dec 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-13
Non-syntrophic methanogenic hydrocarbon degradation by an archaeal species

‘Candidatus Methanoliparum’ overexpresses genes encoding alkyl-coenzyme M and methyl-coenzyme M reductases—markers of archaeal multicarbon alkane and methane metabolism—and thrives on a variety of long-chain alkanes and n-alkylcyclohexanes, and n-alkylbenzenes with long n-alkyl (C_≥13) moieties.

Zhuo Zhou
Cui-jing Zhang
Lei Cheng
Research22 Dec 2021
Nature

Volume: 601, P: 257-262
Predicting the impact of climate change on the distribution of rhododendron on the qinghai-xizang plateau using maxent model

Sen-Xin Chai
Li-Ping Ma
Guo-Ying Zhou
ResearchOpen Access24 Mar 2025
Scientific Reports

Volume: 15, P: 1-13
The protective effects of Polygonum multiflorum stilbeneglycoside preconditioning in an ischemia/reperfusion model of HUVECs

Li-ping Liu
Zhang-ping Liao
Ming He
Research15 Mar 2010
Acta Pharmacologica Sinica

Volume: 31, P: 405-412
Semaglutide ameliorates metabolic disorders in offspring via regulation of oocyte ROS of pre-pregnancy obesity mice

Jun-kai Zhang
Xiao-ping Li
Chun-yu Zeng
Research21 Feb 2025
Acta Pharmacologica Sinica

Volume: 46, P: 1664-1675
Both direct and indirect suppression of MCL1 synergizes with BCLXL inhibition in preclinical models of gastric cancer

Li-Ping Zhang
Yu-Min Wei
Jia-Nan Gong
ResearchOpen Access12 Mar 2025
Cell Death & Disease

Volume: 16, P: 1-16
Boosting lithium storage in covalent organic framework via activation of 14-electron redox chemistry

Conjugated polymeric molecules are promising electrode materials for batteries. Here the authors show a two-dimensional few-layered covalent organic framework that delivers a large reversible capacity of more than 1500 mAh g⁻¹ with the storage mechanism governed by 14-electron redox chemistry.

Zhendong Lei
Qinsi Yang
Yong Wang
ResearchOpen Access08 Feb 2018
Nature Communications

Volume: 9, P: 1-13
Enhanced agricultural sustainability through within-species diversification

Maintaining food security by increasing smallholder production is a global sustainability concern. This study uses field trials on potatoes to demonstrate the positive impact of within-species diversification on yield, disease resistance and improved soil health.

Li-Na Yang
Zhe-Chao Pan
Jiasui Zhan
Research10 Jan 2019
Nature Sustainability

Volume: 2, P: 46-52
Unusual KIE and dynamics effects in the Fe-catalyzed hetero-Diels-Alder reaction of unactivated aldehydes and dienes

Recently an iron catalyst was developed to catalyze an oxa-Diels-Alder reaction, whose mechanism is unclear yet. Here the authors combine DFT and molecular dynamics simulations with experimental studies to elucidate the unusual iron effect on kinetic isotope effect and dynamics in this reaction.

Yuhong Yang
Xiaoyong Zhang
Lung Wa Chung
ResearchOpen Access15 Apr 2020
Nature Communications

Volume: 11, P: 1-10
Synergism of irbesartan and amlodipine on hemodynamic amelioration and organ protection in spontaneously hypertensive rats

Wen Shang
Ping Han
He-hui Xie
Research01 Aug 2011
Acta Pharmacologica Sinica

Volume: 32, P: 1109-1115
Single-photon pulse induced giant response in N > 100 qubit system

Li-Ping Yang
Zubin Jacob
ResearchOpen Access03 Sept 2020
npj Quantum Information

Volume: 6, P: 1-6
Phosphorylated heat shock protein 27 is involved in enhanced heart tolerance to ischemia in short-term type 1 diabetic rats

Hong Chen
Xing-jun Wu
Wenjun Yuan
Research01 Jul 2005
Acta Pharmacologica Sinica

Volume: 26, P: 806-812
Detection of an anti-angina therapeutic module in the effective population treated by a multi-target drug Danhong injection: a randomized trial

Jun Liu
Dan-Dan Li
Zhong Wang
ResearchOpen Access01 Sept 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-10
Contrast-enhanced transrectal ultrasound for prediction of prostate cancer aggressiveness: The role of normal peripheral zone time-intensity curves

Hui Huang
Zheng-Qiu Zhu
Li-Ping Yin
ResearchOpen Access08 Dec 2016
Scientific Reports

Volume: 6, P: 1-8
Synergistic effects of atenolol and amlodipine for lowering and stabilizing blood pressure in 2K1C renovascular hypertensive rats

Fu-ming Shen
He-hui Xie
Ding-feng Su
Research01 Nov 2005
Acta Pharmacologica Sinica

Volume: 26, P: 1303-1308
Transcriptomic decoding of regional cortical vulnerability to major depressive disorder

Our combined large-scale neuroimaging and brain transcriptome study demonstrates genetic substrates underlying cortical functional abnormalities in depression, suggesting transcriptomic decoding of regional cortical vulnerability to depression.

Jiajia Zhu
Xiao Chen
Yongqiang Yu
ResearchOpen Access08 Aug 2024
Communications Biology

Volume: 7, P: 1-12
Development of orthotopic mouse models for mid-low rectal cancer

Wen Chen
Kun Shi
Zhi-yong Qian
Research12 Feb 2025
Acta Pharmacologica Sinica

Volume: 46, P: 1772-1781
Design, synthesis and antitumor evaluation of a new series of N-substituted-thiourea derivatives

Jian Li
Jin-zhi Tan
Hua-liang Jiang
Research01 Sept 2006
Acta Pharmacologica Sinica

Volume: 27, P: 1259-1271
XELOX (capecitabine plus oxaliplatin) plus bevacizumab (anti-VEGF-A antibody) with or without adoptive cell immunotherapy in the treatment of patients with previously untreated metastatic colorectal cancer: a multicenter, open-label, randomized, controlled, phase 3 trial

Qiu-Zhong Pan
Jing-Jing Zhao
Jian-Chuan Xia
ResearchOpen Access03 Apr 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-10
Robust and accurate prediction of protein–protein interactions by exploiting evolutionary information

Yang Li
Zheng Wang
Yan-Bin Wang
ResearchOpen Access19 Aug 2021
Scientific Reports

Volume: 11, P: 1-12
PEX3 promotes regenerative repair after myocardial injury in mice through facilitating plasma membrane localization of ITGB3

The authors show that PEX3, as an essential regulator of peroxisome-related functions, promote myocardial regenerative repair through plasmalogen metabolism, facilitating plasma membrane localization of ITGB3 and activating the AKT/GSK3β signaling pathway.

Jia-Teng Sun
Zi-Mu Wang
Lian-Sheng Wang
ResearchOpen Access01 Jul 2024
Communications Biology

Volume: 7, P: 1-20
GRK5 functions as an oncogenic factor in non-small-cell lung cancer

Li-Ping Jiang
Song-Qing Fan
Yong-Bin Chen
ResearchOpen Access20 Feb 2018
Cell Death & Disease

Volume: 9, P: 1-12
mTORC2 acts as a gatekeeper for mTORC1 deficiency-mediated impairments in ILC3 development

Ya-fei Deng
Shu-ting Wu
You-cai Deng
Research05 Jul 2023
Acta Pharmacologica Sinica

Volume: 44, P: 2243-2252
Comprehensive metabolomics expands precision medicine for triple-negative breast cancer

Yi Xiao
Ding Ma
Yi-Zhou Jiang
ResearchOpen Access01 Feb 2022
Cell Research

Volume: 32, P: 477-490
Treatment outcome and efficacy of therapeutic plasma exchange for transplant-associated thrombotic microangiopathy in a large real-world cohort study

Li-Ping Yang
Peng Zhao
Xiao-Hui Zhang
Research25 Jan 2022
Bone Marrow Transplantation

Volume: 57, P: 554-561
Characterization of LTr1 derived from cruciferous vegetables as a novel anti-glioma agent via inhibiting TrkA/PI3K/AKT pathway

Qi-qi Song
Li-ping Lin
Gang Hu
Research08 Dec 2022
Acta Pharmacologica Sinica

Volume: 44, P: 1262-1276
Tektin4 loss promotes triple-negative breast cancer metastasis through HDAC6-mediated tubulin deacetylation and increases sensitivity to HDAC6 inhibitor

Li-Ping Ge
Xi Jin
Yi-Zhou Jiang
Research02 Mar 2021
Oncogene

Volume: 40, P: 2323-2334
NCAPH plays important roles in human colon cancer

Liang Yin
Li-Ping Jiang
Yong-Bin Chen
ResearchOpen Access16 Mar 2017
Cell Death & Disease

Volume: 8, P: e2680
Cav3.1-driven bursting firing in ventromedial hypothalamic neurons exerts dual control of anxiety-like behavior and energy expenditure

Jie Shao
Da-Shuang Gao
Fan Yang
ResearchOpen Access22 Mar 2022
Molecular Psychiatry

Volume: 27, P: 2901-2913
High rate of drug resistance among tuberculous meningitis cases in Shaanxi province, China

Ting Wang
Guo-Dong Feng
Gang Zhao
ResearchOpen Access04 May 2016
Scientific Reports

Volume: 6, P: 1-10
A National Assessment of the Epidemiology of Severe Fever with Thrombocytopenia Syndrome, China

Kun Liu
Hang Zhou
Wu-Chun Cao
ResearchOpen Access23 Apr 2015
Scientific Reports

Volume: 5, P: 1-8
MiR-27a rs895819 is involved in increased atrophic gastritis risk, improved gastric cancer prognosis and negative interaction with Helicobacter pylori

Qian Xu
Tie-jun Chen
Yuan Yuan
ResearchOpen Access02 Feb 2017
Scientific Reports

Volume: 7, P: 1-11

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