Two series of fluorescent glycopolymers (boronic acid derivatives, PG-PFE, and borate derivatives, PG-PFW) were synthesized through different methods. Compared with the PG-PFE samples, the PG-PFW samples had a higher grafting ratio due to the highly efficient Williamson reaction. The fluorescent glycopolymers possessed good water solubility, low cytotoxicity and selective responsiveness toward H2O2. Meantime, the fluorescent glycopolymers were imaged only in cellular mitochondria based on the fact that endogenous H2O2 is mainly distributed in cellular mitochondria.
- Yuangong Zhang
- Libin Bai
- Xinwu Ba
