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Showing 1–3 of 3 results
Advanced filters: Author: Liu-Yan Zhu Clear advanced filters

  • Carbon dots have attracted much attention for biomedical applications but potential degradation and associated toxicity are still poorly understood. Here, the authors report on a study into the photo-degradation of carbon dots, the products produced and associated cytotoxicity.

    • Yue-Yue Liu
    • Nan-Yang Yu
    • Ai-Jun Miao
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12

  • GPM6A expression is markedly suppressed in hepatocellular carcinoma and suppresses proliferation and migration of hepatoma cells. Moreover, its low expression is most likely attributed to upregulated miRNA-96-5p but not gene mutation or changes in methylation. These findings indicate that GPM6A may function as an inhibitory gene in chronic information, fibrosis and oncogenic transformation.

    • Zong-Rui Li
    • Gang Xu
    • Jian Wu
    Research
    Laboratory Investigation
    Volume: 102, P: 1280-1291

  • The findings of the present study demonstrate that inflammasome NLRP3 deficiency did not attenuate, but enhanced hepatocellular steatosis, injury and death, inflammation, and fibrosis, as well as insulin resistance in both liver and adipose tissues. This effect is probably due to an enhanced inflammatory response with elevated monocyte chemotactic protein-1 and M1 microphages.

    • Liu-Yan Zhu
    • Chang Liu
    • Jian Wu
    Research
    Laboratory Investigation
    Volume: 101, P: 588-599