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Advanced filters: Author: Lukas Baitsch Clear advanced filters

  • Through gene knockout experiments, Sicinski and colleagues reveal a role for cyclin C as a haploinsufficient tumour suppressor in T-cell acute lymphoblastic leukaemia, acting through phosphorylation of intracellular Notch1, mediating its degradation.

    • Na Li
    • Anne Fassl
    • Piotr Sicinski
    Research
    Nature Cell Biology
    Volume: 16, P: 1080-1091