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Showing 1–8 of 8 results
Advanced filters: Author: Lydia Potekhina Clear advanced filters
  • Combined patch clamp recording, biocytin staining and single-cell RNA-sequencing of human neurocortical neurons shows an expansion of glutamatergic neuron types relative to mouse that characterizes the greater complexity of the human neocortex.

    • Jim Berg
    • Staci A. Sorensen
    • Ed S. Lein
    ResearchOpen Access
    Nature
    Volume: 598, P: 151-158
  • A high-resolution gene expression atlas of prenatal and postnatal brain development of rhesus monkey charts global transcriptional dynamics in relation to brain maturation, while comparative analysis reveals human-specific gene trajectories; candidate risk genes associated with human neurodevelopmental disorders tend to be co-expressed in disease-specific patterns in the developing monkey neocortex.

    • Trygve E. Bakken
    • Jeremy A. Miller
    • Ed S. Lein
    Research
    Nature
    Volume: 535, P: 367-375
  • The authors developed an optimized rabies tracing system for generating brain-wide monosynaptic input connectomes, and applied it in mouse visual cortex to reveal topographically organized subnetworks co-defined by visual areas, layers and cell classes.

    • Shenqin Yao
    • Quanxin Wang
    • Hongkui Zeng
    Research
    Nature Neuroscience
    Volume: 26, P: 350-364
  • A spatially resolved transcriptional atlas of the mid-gestational developing human brain has been created using laser-capture microdissection and microarray technology, providing a comprehensive reference resource which also enables new hypotheses about the nature of human brain evolution and the origins of neurodevelopmental disorders.

    • Jeremy A. Miller
    • Song-Lin Ding
    • Ed S. Lein
    Research
    Nature
    Volume: 508, P: 199-206
  • Multi-modal analysis is used to generate a 3D atlas of the upper limb area of the mouse primary motor cortex, providing a framework for future studies of motor control circuitry.

    • Rodrigo Muñoz-Castañeda
    • Brian Zingg
    • Hong-Wei Dong
    ResearchOpen Access
    Nature
    Volume: 598, P: 159-166
  • Laser microdissection and microarrays are used to assess 900 precise subdivisions of the brains from three healthy men with 60,000 gene expression probes; the resulting atlas allows comparisons between humans and other animals, and will facilitate studies of human neurological and psychiatric diseases.

    • Michael J. Hawrylycz
    • Ed S. Lein
    • Allan R. Jones
    Research
    Nature
    Volume: 489, P: 391-399