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TMEFF1 is a neuron-specific restriction factor for herpes simplex virus

A study identifies TMEFF1 as a neuron-specific restriction factor essential for prevention of replication of herpes simplex virus type 1 in the central nervous system.

Yao Dai
Manja Idorn
Søren R. Paludan
Research24 Jul 2024
Nature

Volume: 632, P: 383-389
Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

David Olagnier
Ensieh Farahani
Christian K. Holm
Amendments and CorrectionsOpen Access21 Oct 2020
Nature Communications

Volume: 11, P: 1
Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma

Norbert Hilf
Sabrina Kuttruff-Coqui
Wolfgang Wick
Amendments and Corrections07 Feb 2019
Nature

Volume: 566, P: E13
Capsid-like particles decorated with the SARS-CoV-2 receptor-binding ___domain elicit strong virus neutralization activity

Here the authors generate a capsid-like particle based vaccine candidate displaying the receptor-binding ___domain of the SARS-CoV-2 spike protein and show induction of neutralizing antibodies after intramuscular prime-boost immunization in mice.

Cyrielle Fougeroux
Louise Goksøyr
Adam F. Sander
ResearchOpen Access12 Jan 2021
Nature Communications

Volume: 12, P: 1-11
SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

Viral infections usually cause disease through direct cytopathogenic effects and excessive inflammatory responses. Here, Olagnier et al. show that two NRF2 agonists, 4-OI and DMF, possess broad IFN-independent antiviral activity and decrease host inflammatory response to SARS-CoV-2 infection.

David Olagnier
Ensieh Farahani
Christian K. Holm
ResearchOpen Access02 Oct 2020
Nature Communications

Volume: 11, P: 1-12
Actively personalized vaccination trial for newly diagnosed glioblastoma

In a phase I trial, highly individualized peptide vaccines against unmutated tumour antigens and neoepitopes elicited sustained responses in CD8⁺ and CD4⁺ T cells, respectively, in patients with newly diagnosed glioblastoma.

Norbert Hilf
Sabrina Kuttruff-Coqui
Wolfgang Wick
Research19 Dec 2018
Nature

Volume: 565, P: 240-245
Broadly potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages

Isolation of a broad and potent neutralizing human monoclonal antibody which targets a conserved N-terminal epitope and neutralizes Omicron sub-lineages, including BA.2.86 and JN.1, offers insights into immune evasion mechanisms.

Melanie R. Walker
Alexander Underwood
Lea Barfod
ResearchOpen Access02 Oct 2024
Communications Biology

Volume: 7, P: 1-14

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TMEFF1 is a neuron-specific restriction factor for herpes simplex virus

Author Correction: SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma

Capsid-like particles decorated with the SARS-CoV-2 receptor-binding ___domain elicit strong virus neutralization activity

SARS-CoV2-mediated suppression of NRF2-signaling reveals potent antiviral and anti-inflammatory activity of 4-octyl-itaconate and dimethyl fumarate

Actively personalized vaccination trial for newly diagnosed glioblastoma

Broadly potent spike-specific human monoclonal antibodies inhibit SARS-CoV-2 Omicron sub-lineages

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