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Showing 1–7 of 7 results

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Functional multi-organelle units control inflammatory lipid metabolism of macrophages

Zimmermann et al. present OrgaPlexing, an imaging pipeline mapping metabolic organelles and their interactions. They find changes in mitochondria, ER, peroxisome and lipid droplet dynamics that impact macrophage inflammatory lipid mediator synthesis.

Julia A. Zimmermann
Kerstin Lucht
Angelika S. Rambold
ResearchOpen Access05 Jul 2024
Nature Cell Biology

Volume: 26, P: 1261-1273
Genome-guided design of a defined mouse microbiota that confers colonization resistance against Salmonella enterica serovar Typhimurium

A minimal bacterial community has been defined that provides colonization resistance to Salmonella enterica serovar Typhimurium once established in germ-free mice to a similar extent as a conventional microbial community.

Sandrine Brugiroux
Markus Beutler
Bärbel Stecher
Research21 Nov 2016
Nature Microbiology

Volume: 2, P: 1-12
Ecophysiology and interactions of a taurine-respiring bacterium in the mouse gut

Authors utilise a multi-omics approach for the ecophysiological characterization of a taurine-respiring mouse gut bacterium.

Huimin Ye
Sabrina Borusak
Alexander Loy
ResearchOpen Access18 Sept 2023
Nature Communications

Volume: 14, P: 1-15
Catchup: a mouse model for imaging-based tracking and modulation of neutrophil granulocytes

Cre recombinase and tdTomato expressed from a neutrophil-specific promoter allow highly specific genetic manipulation and labeling of neutrophils.

Anja Hasenberg
Mike Hasenberg
Matthias Gunzer
Research16 Mar 2015
Nature Methods

Volume: 12, P: 445-452
Slow integrin-dependent migration organizes networks of tissue-resident mast cells

Immune cells are generally considered to be able to move through tissues using nonadhesive amoeboid migration mechanics. Here, the authors show that, unlike other immune cells, mast cells do not use this method and instead are completely reliant on integrin–ECM interactions.

Lukas Kaltenbach
Paloma Martzloff
Tim Lämmermann
ResearchOpen Access20 Apr 2023
Nature Immunology

Volume: 24, P: 915-924
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22