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Advanced filters: Author: Mark A. Matulenko Clear advanced filters

  • An orally bioavailable small-molecule active-site inhibitor of the phosphatases PTPN2 and PTPN1, ABBV-CLS-484, demonstrates immunotherapeutic efficacy in mouse models of cancer resistant to PD-1 blockade.

    • Christina K. Baumgartner
    • Hakimeh Ebrahimi-Nik
    • Robert T. Manguso
    ResearchOpen Access
    Nature
    Volume: 622, P: 850-862