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Advanced filters: Author: Martin Arhin Clear advanced filters
  • SPP1+ macrophages and CD8 + exhausted T cells are known to crosstalk. Here, the authors discover that extrahepatic tumors facilitate liver metastasis by promoting the formation of an intermediate macrophage population in the liver that inhibits tumor-reactive CD8+ T cell function.

    • Rajiv Trehan
    • Patrick Huang
    • Tim F. Greten
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-20