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Showing 51–100 of 127 results

Advanced filters: Author: Martin Jaeger Clear advanced filters

Overexpression of the bcl-2 oncogene in the mouse pre-B cell line SPGM-1 protects from apoptosis, but does not affect blocked B-lineage differentiation and lineage switch towards macrophage like cells

Detlef Neumann
Andreas Strasser
Michael Uwe Martin
Research01 Oct 1997
Cell Death & Differentiation

Volume: 4, P: 580-589
Short-term outcome after treatment of talocrural instability in cats using modified type II transarticular external skeletal fixation

Shaaban Gadallah
Mohamed El-Sunsafty
Amal Hammad
ResearchOpen Access02 Apr 2024
Scientific Reports

Volume: 14, P: 1-9
Whole-genome sequencing of bladder cancers reveals somatic CDKN1A mutations and clinicopathological associations with mutation burden

Bladder cancer is a complex genetic disease and a common cause of death due to malignancy. Here, the authors carry out whole-genome sequencing of 14 bladder cancers to characterize the genomic landscape of the disease and show that mutational burden is associated with tumour progression in these samples.

J. -B. Cazier
S. R. Rao
F. C. Hamdy
ResearchOpen Access29 Apr 2014
Nature Communications

Volume: 5, P: 1-13
The delay of shock breakout due to circumstellar material evident in most type II supernovae

The shock breakout (SBO) is the first electromagnetic signature of a supernova (SN) explosion. Förster et al. find that in nearly all type II SNe they survey that the SBO occurs on a timescale of days, indicating that the progenitors were surrounded by thick circumstellar matter when they exploded.

F. Förster
T. J. Moriya
D. R. Young
Research03 Sept 2018
Nature Astronomy

Volume: 2, P: 808-818
Oral Transforming Growth Factor-α Enhances Jejunal Mucosal Recovery and Electrical Resistance in Piglet Rotavirus Enteritis

J Marc Rhoads
Martin H Ulshen
James G Lecce
Research01 Aug 1995
Pediatric Research

Volume: 38, P: 173-181
Plasma markers of neurodegeneration, latent cognitive abilities and physical activity in healthy aging

Jonna Nilsson
Yiwen Jiang
Maria Ekblom
ResearchOpen Access17 Sept 2024
Scientific Reports

Volume: 14, P: 1-12
Insights into the accuracy of social scientists’ forecasts of societal change

How accurate are social scientists in predicting societal change, and what processes underlie their predictions? Grossmann et al. report the findings of two forecasting tournaments. Social scientists’ forecasts were on average no more accurate than those of simple statistical models.

Igor Grossmann
Amanda Rotella
Tom Wilkening
Research09 Feb 2023
Nature Human Behaviour

Volume: 7, P: 484-501
A physical map of the mouse genome

Simon G. Gregory
Mandeep Sekhon
David R. Bentley
Research04 Aug 2002
Nature

Volume: 418, P: 743-750
Recurrent chromosomal gains and heterogeneous driver mutations characterise papillary renal cancer evolution

Papillary renal cell carcinoma (pRCC) is a subtype of kidney cancer characterized by highly variable clinical behaviour. Here the authors sequence either the genomes or exomes of 31 pRCCs and identify several genes in sub-clones and large copy number variants in major clones that may be important drivers of pRCC.

Michal Kovac
Carolina Navas
Ian Tomlinson
ResearchOpen Access19 Mar 2015
Nature Communications

Volume: 6, P: 1-11
Genomic and transcriptomic changes complement each other in the pathogenesis of sporadic Burkitt lymphoma

Burkitt lymphoma (BL) is the most common pediatric B-cell lymphoma. Here, within the International Cancer Genome Consortium, the authors performed whole genome and transcriptome sequencing of 39 sporadic BL, describing the landscape of mutations, structural variants, and mutational processes that underpin this disease how alterations on different cellular levels cooperate in deregulating key pathways and complexes.

Cristina López
Kortine Kleinheinz
Reiner Siebert
ResearchOpen Access29 Mar 2019
Nature Communications

Volume: 10, P: 1-19
Genetic deficiency of NOD2 confers resistance to invasive aspergillosis

NOD2 has been shown to be crucial for immune recognition of Aspergillus infection. Here the authors show that a common NOD2 genetic variant associated with Crohn’s disease is associated with reduced risk of disease due to enhanced antifungal activates of monocytes and macrophages.

Mark S. Gresnigt
Cristina Cunha
Frank L. van de Veerdonk
ResearchOpen Access06 Jul 2018
Nature Communications

Volume: 9, P: 1-15
Publisher Correction: JunB is a key regulator of multiple myeloma bone marrow angiogenesis

Fengjuan Fan
Stefano Malvestiti
Klaus Podar
Amendments and CorrectionsOpen Access06 Sept 2021
Leukemia

Volume: 35, P: 3628
A higher BMI is not associated with a different immune response and disease course in critically ill COVID-19 patients

Emma J. Kooistra
Aline H. de Nooijer
Irma Joosten
Research25 Jan 2021
International Journal of Obesity

Volume: 45, P: 687-694
Author Correction: A multi-country test of brief reappraisal interventions on emotions during the COVID-19 pandemic

Ke Wang
Amit Goldenberg
Hannah Moshontz
Amendments and Corrections24 Aug 2022
Nature Human Behaviour

Volume: 6, P: 1318-1319
Development of the signal in sensory rhodopsin and its transfer to the cognate transducer

Rouslan Moukhametzianov
Johann P. Klare
Valentin I. Gordeliy
Research01 Feb 2006
Nature

Volume: 440, P: 115-119
Specific Approach on Dose-Response Curves to Inhaled Carbachol Assessed by the Interruption Technique in Children

Cornelia Wirz Sommer
Urs Frey
Richard Kraemer
Research01 Oct 1993
Pediatric Research

Volume: 34, P: 478-483
SYNERGISTIC ON AUXIN AND CYTOKININ 1 positively regulates growth and attenuates soil pathogen resistance

Cytokinin and auxin are two major hormonal regulators of plant growth. Here the authors identify SYAC1, a gene that is synergistically activated by the two hormones being applied together, and show that it is required for normal growth while negatively impacting pathogen resistance.

Andrej Hurný
Candela Cuesta
Eva Benková
ResearchOpen Access01 May 2020
Nature Communications

Volume: 11, P: 1-17
Measurement of matter–antimatter differences in beauty baryon decays

CP violation has deep implications for particle physics and cosmology. Previously observed only in meson decays, signs of CP violation have now been spotted in baryon decays by analysing the proton–proton collision data from the LHCb detector.

R. Aaij
B. Adeva
S. Zucchelli
ResearchOpen Access30 Jan 2017
Nature Physics

Volume: 13, P: 391-396
Author Correction: The delay of shock breakout due to circumstellar material evident in most type II supernovae

F. Förster
T. J. Moriya
D. R. Young
Amendments and Corrections12 Nov 2018
Nature Astronomy

Volume: 3, P: 107
Osteopenia and Osteoporosis in Patients with Bronchiectasis: Association with Respiratory Parameters, Body Composition, Muscle Strength and Bone Remodeling Biomarkers

V. Contreras-Bolívar
G. Olveira
C. Olveira
ResearchOpen Access10 Oct 2019
Scientific Reports

Volume: 9, P: 1-10
Understanding human immune function using the resources from the Human Functional Genomics Project

Mihai G Netea
Leo A B Joosten
Cisca Wijmenga
Correspondence04 Aug 2016
Nature Medicine

Volume: 22, P: 831-833
Acute BAF perturbation causes immediate changes in chromatin accessibility

Acute degradation of the BAF subunit SMARCA4 shows rapid chromatin accessibility changes, thus suggesting that maintenance of genome accessibility requires constant ATP-dependent remodeling.

Sandra Schick
Sarah Grosche
Stefan Kubicek
Research08 Feb 2021
Nature Genetics

Volume: 53, P: 269-278
Hereditary mixed polyposis syndrome is caused by a 40-kb upstream duplication that leads to increased and ectopic expression of the BMP antagonist GREM1

Ian Tomlinson and colleagues identify a 40-kb duplication upstream of the gene that encodes the BMP antagonist GREM1 in families with hereditary mixed polyposis syndrome. The mutation is associated with increased allele-specific and ectopic expression of GREM1.

Emma Jaeger
Simon Leedham
Ian Tomlinson
Research06 May 2012
Nature Genetics

Volume: 44, P: 699-703
Designer cells programming quorum-sensing interference with microbes

Bacterial populations communicate with AI-2 signaling molecules, helping to coordinate biofilm development and other group behaviors. Here the authors design a genetic circuit for mammalian cells that allows them to sense bacterial populations and interfere with quorum communication.

Ferdinand Sedlmayer
Dennis Hell
Martin Fussenegger
ResearchOpen Access08 May 2018
Nature Communications

Volume: 9, P: 1-13
Author Correction: The landscape of genomic alterations across childhood cancers

Susanne N. Gröbner
Barbara C. Worst
Stephanie Sungalee
Amendments and Corrections06 Jun 2018
Nature

Volume: 559, P: E10
Observation of the rare B_s⁰ →µ⁺µ⁻ decay from the combined analysis of CMS and LHCb data

Combined analysis of proton-proton collision data from the Large Hadron Collider at CERN by the CMS and LHCb collaborations leads to the observation of the extremely rare decay of the strange B meson into muons; the result is compatible with the standard model of particle physics, and does not show any signs of new physics, such as supersymmetry.

V. Khachatryan
A.M. Sirunyan
E. Pesen
ResearchOpen Access13 May 2015
Nature

Volume: 522, P: 68-72
Metabolic cost of unloading pedalling in different groups of patients with pulmonary hypertension and volunteers

Till Ittermann
Sabine Kaczmarek
Ralf Ewert
ResearchOpen Access05 Mar 2024
Scientific Reports

Volume: 14, P: 1-9
Publisher Correction: Situational factors shape moral judgements in the trolley dilemma in Eastern, Southern and Western countries in a culturally diverse sample

Bence Bago
Marton Kovacs
Balazs Aczel
Amendments and Corrections06 Jun 2022
Nature Human Behaviour

Volume: 6, P: 897-898
Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Clara Grilo
Tomé Neves
Eric Guinard
ResearchOpen Access31 Mar 2025
Scientific Data

Volume: 12, P: 1-14
Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer

Richard Houlston and colleagues identify four new susceptibility loci for colorectal cancer through a meta-analysis of genome-wide association data, followed by replication testing in a large collection of independent samples. The study brings to ten the number of confirmed loci harboring low-penetrance risk alleles for this common malignancy.

Richard S Houlston
Emily Webb
Malcolm G Dunlop
Research16 Nov 2008
Nature Genetics

Volume: 40, P: 1426-1435
Using mobile EEG to study auditory work strain during simulated surgical procedures

Marc Rosenkranz
Thorge Haupt
Martin G. Bleichner
ResearchOpen Access14 Oct 2024
Scientific Reports

Volume: 14, P: 1-15
Recognition of DHN-melanin by a C-type lectin receptor is required for immunity to Aspergillus

The C-type lectin receptor MelLec recognizes DHN-melanin in conidial spores of Aspergillus fumigatus and other DHN-melanized fungi, revealing an important role for this receptor in antifungal immunity in both mice and humans.

Mark H. T. Stappers
Alexandra E. Clark
Gordon D. Brown
Research28 Feb 2018
Nature

Volume: 555, P: 382-386
Integration of multi-omics data and deep phenotyping enables prediction of cytokine responses

The immune response to pathogens varies substantially among humans. Netea and colleagues show that integration of multi-omics data and deep phenotyping enables prediction of cytokine production in responses to pathogens.

Olivier B. Bakker
Raul Aguirre-Gamboa
Yang Li
Research21 May 2018
Nature Immunology

Volume: 19, P: 776-786
Ex vivo expansion of circulating tumour cells (CTCs)

Bashir M. Mohamed
Mark P. Ward
John J. O’Leary
ResearchOpen Access06 Mar 2023
Scientific Reports

Volume: 13, P: 1-13
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33

Ian Tomlinson, Richard Houlston, Malcolm Dunlop and colleagues report results of a large genome-wide association study of colorectal cancer. They identify four new risk loci and suggest that many more loci of similar effect size are likely to exist.

Richard S Houlston
Jeremy Cheadle
Ian P M Tomlinson
Research24 Oct 2010
Nature Genetics

Volume: 42, P: 973-977
Towards the sustainable discovery and development of new antibiotics

Antimicrobial resistance is an increasing threat to public health and encouraging the development of new antimicrobials is one of the most important ways to address the problem. This Roadmap article aims to bring together industrial, academic and political partners, and proposes both short-term and long-term solutions to this challenge.

Marcus Miethke
Marco Pieroni
Rolf Müller
Reviews19 Aug 2021
Nature Reviews Chemistry

Volume: 5, P: 726-749
Structured exercise alters the gut microbiota in humans with overweight and obesity—A randomized controlled trial

Timo Kern
Martin Bæk Blond
Bente Stallknecht
Research29 Aug 2019
International Journal of Obesity

Volume: 44, P: 125-135
Author Correction: A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

G. Aad
B. Abbott
L. Zwalinski
Amendments and CorrectionsOpen Access18 Oct 2023
Nature

Volume: 623, P: E5
Quadriceps physiological response during the 1-min sit-to-stand test in people with severe COPD and healthy controls

Sarah Gephine
Patrick Mucci
François Maltais
ResearchOpen Access17 Jan 2022
Scientific Reports

Volume: 12, P: 1-10
On the single and multiple associations of COVID-19 post-acute sequelae: 6-month prospective cohort study

Beatriz María Jiménez-Rodríguez
José Gutiérrez-Fernández
Concepción Morales-García
ResearchOpen Access01 Mar 2022
Scientific Reports

Volume: 12, P: 1-12
Intact sensory-motor network structure and function in far from onset premanifest Huntington’s disease

Martin Gorges
Hans-Peter Müller
Michael Orth
ResearchOpen Access07 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Higher VO₂max is associated with thicker cortex and lower grey matter blood flow in older adults

Gaia Olivo
Jonna Nilsson
Martin Lövdén
ResearchOpen Access18 Aug 2021
Scientific Reports

Volume: 11, P: 1-13
A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

Ian PM Tomlinson
Emily Webb
Richard S Houlston
Research30 Mar 2008
Nature Genetics

Volume: 40, P: 623-630
The effect of host genetics on the gut microbiome

Alexandra Zhernakova, Jingyuan Fu, Cisca Wijmenga and colleagues perform genome-wide association analysis for microbiome characteristics in a cohort with fully sequenced metagenomes and detailed diet and lifestyle data. They find loci significantly associated with different microbial species, pathways and genes and examine specific gene–diet interactions.

Marc Jan Bonder
Alexander Kurilshikov
Alexandra Zhernakova
Research03 Oct 2016
Nature Genetics

Volume: 48, P: 1407-1412
Inter-individual variability and genetic influences on cytokine responses to bacteria and fungi

A systematic analysis reveals some genetic variation underpinning the heterogeneity in pathogen-induced cytokine production by blood cells from a cohort of healthy individuals.

Yang Li
Marije Oosting
Mihai G Netea
Research04 Jul 2016
Nature Medicine

Volume: 22, P: 952-960
N¹-methylnicotinamide is a signalling molecule produced in skeletal muscle coordinating energy metabolism

Kristoffer Ström
David Morales-Alamo
Ola Hansson
ResearchOpen Access14 Feb 2018
Scientific Reports

Volume: 8, P: 1-12
Analysis of population structures of the microalga Acutodesmus obliquus during lipid production using multi-dimensional single-cell analysis

Michael Sandmann
Michaela Schafberg
Sascha Rohn
ResearchOpen Access19 Apr 2018
Scientific Reports

Volume: 8, P: 1-9
Acute increases in brain-derived neurotrophic factor in plasma following physical exercise relates to subsequent learning in older adults

Jonna Nilsson
Örjan Ekblom
Martin Lövdén
ResearchOpen Access10 Mar 2020
Scientific Reports

Volume: 10, P: 1-15
Fibroblast Growth Factor 2 Activation of Stromal Cell Vascular Endothelial Growth Factor Expression and Angiogenesis

Kevin P Claffey
Kristin Abrams
Martin Keough
Research01 Jan 2001
Laboratory Investigation

Volume: 81, P: 61-75
Environmental challenges for the Belt and Road Initiative

The Belt and Road Initiative will greatly influence the future of global trade. However, it may also promote permanent environmental degradation. We call for rigorous strategic environmental and social assessments, raising the bar for environmental protection worldwide.

Fernando Ascensão
Lenore Fahrig
Henrique M. Pereira
Comments & Opinion15 May 2018
Nature Sustainability

Volume: 1, P: 206-209

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