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Showing 1–3 of 3 results
Advanced filters: Author: Maryam Pourmaleki Clear advanced filters

  • Multi-modal analysis of genomically unstable ovarian tumours characterizes the contribution of anatomical sites and mutational processes to evolutionary phenotypic divergence and immune resistance mechanisms.

    • Ignacio Vázquez-García
    • Florian Uhlitz
    • Sohrab P. Shah
    ResearchOpen Access
    Nature
    Volume: 612, P: 778-786

  • The epidermal growth factor receptor (EGFR) signalling is regulated at multiple levels. Here the authors show that the importin RanBP6 acts as a tumor suppressor in Glioblastoma and  regulates EGFR signalling through promoting translocation of STAT3 to the nuclei and repressing EGFR transcription.

    • Barbara Oldrini
    • Wan-Ying Hsieh
    • Ingo K. Mellinghoff
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-12