Gonçalo Abecasis, Dajiang Liu and colleagues report a meta-analysis framework to identify rare variant associations based on gene-level tests and the use of shared summary statistics provided by individual studies. They demonstrate their approach on a meta-analysis of blood lipid levels including 18,699 individuals, drawn from across 7 studies and genotyped with exome arrays.
- Dajiang J Liu
- Gina M Peloso
- Gonçalo R Abecasis
