Nature Search

A stable backbone for the fungi

Ingo Ebersberger
Matthias Gube
Arndt von Haeseler
ResearchOpen Access25 Feb 2009
Nature Precedings

P: 1
Nicotinamide modulates gut microbial metabolic potential and accelerates recovery in mild-to-moderate COVID-19

In a prospective, double-blind, randomized, placebo-controlled trial, supplementation with a combination of conventional and gut-targeted nicotinamide was safe and effective in ameliorating COVID-19 symptoms.

Stefan Schreiber
Georg H. Waetzig
Philip Rosenstiel
ResearchOpen Access12 May 2025
Nature Metabolism

Volume: 7, P: 1136-1149
Author Correction: NeoR, a near-infrared absorbing rhodopsin

Matthias Broser
Anika Spreen
Peter Hegemann
Amendments and CorrectionsOpen Access10 May 2024
Nature Communications

Volume: 15, P: 1
COVID-19 death toll predictions show that triggering counterfactual thinking deteriorates judgmental performance

Seifert and Somasundaram collect 6731 daily forecasts over 377 days to investigate the role of triggering counterfactual thinking when interpreting public information regarding the daily US death toll from COVID-19. They find that counterfactual thinking leads to greater judgmental forecasting biases.

Matthias Seifert
Jeeva Somasundaram
ResearchOpen Access04 Feb 2025
Communications Medicine

Volume: 5, P: 1-8
The LDL receptor pathway delivers arachidonic acid for eicosanoid formation in cells stimulated by platelet-derived growth factor

Andreas J. R. Habenicht
Peter Salbach
John A. Glomset
Research14 Jun 1990
Nature

Volume: 345, P: 634-636
NeoR, a near-infrared absorbing rhodopsin

Rhizoclosmatium globosum contains three rhodopsin-guanylyl cyclases (RGCs) predicted to enable visual orientation of zoospores. Here authors show that RGC1 and 2 function as light-activated cyclases only upon heterodimerization with RGC3 (NeoR), a near-infrared absorbing, highly fluorescent rhodopsin.

Matthias Broser
Anika Spreen
Peter Hegemann
ResearchOpen Access10 Nov 2020
Nature Communications

Volume: 11, P: 1-10
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia

A single-cell screening approach identifies targets for CAR-T cells in acute myeloid leukemia.

Adrian Gottschlich
Moritz Thomas
Sebastian Kobold
Research13 Mar 2023
Nature Biotechnology

Volume: 41, P: 1618-1632
Therapeutic targeting of ATR in alveolar rhabdomyosarcoma

Alveolar rhabdomyosarcoma is a clinically challenging disease due to the lack of druggable targets. Here the authors show preclinical evidence for ATR inhibitors as a therapeutic option for alveolar rhabdomyosarcoma.

Heathcliff Dorado García
Fabian Pusch
Anton G. Henssen
ResearchOpen Access25 Jul 2022
Nature Communications

Volume: 13, P: 1-15
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours

Forced expression of C-X-C chemokine receptor type 6 in antigen-specific T cells enhanced the recognition and lysis of pancreatic cancer cells and the efficacy of adoptive cell therapy for pancreatic cancer.

Stefanie Lesch
Viktoria Blumenberg
Sebastian Kobold
Research03 Jun 2021
Nature Biomedical Engineering

Volume: 5, P: 1246-1260
Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification

RNA variants derived from cancer-associated RNA editing events can be a source of neoantigens. Here, based on a proteogenomic pipeline combining DNA and RNA sequencing with MS-based immunopeptidomics, the authors identity and validate potential neoantigen candidates in patients with different tumor entities, highlighting RNA as important neoantigen source.

Celina Tretter
Niklas de Andrade Krätzig
Angela M. Krackhardt
ResearchOpen Access02 Aug 2023
Nature Communications

Volume: 14, P: 1-22
Alternative splicing regulates stochastic NLRP3 activity

Leucine-rich repeat (LRR) domains are commonly present in immune regulatory proteins. Here the authors show that LRR exonic modularity and alternative splicing of an LRR-containing protein, NLRP3, modulate the ratio of functional/afunctional NLRP3 isoforms to instill a stochastic regulation of NLRP3-mediated inflammation and innate immunity.

Florian Hoss
James L. Mueller
Eicke Latz
ResearchOpen Access19 Jul 2019
Nature Communications

Volume: 10, P: 1-13
Author Correction: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification

Celina Tretter
Niklas de Andrade Krätzig
Angela M. Krackhardt
Amendments and CorrectionsOpen Access15 Mar 2024
Nature Communications

Volume: 15, P: 1
Antiviral signalling by a cyclic nucleotide activated CRISPR protease

A CalpL–CalpT–CalpS cascade mediated by cyclic oligoadenylates is identified as a mechanism to detect viral RNA and activate subsequent antivirus responses in microorganisms.

Christophe Rouillon
Niels Schneberger
Gregor Hagelueken
Research24 Nov 2022
Nature

Volume: 614, P: 168-174
Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis

How extracellular calcium can trigger Nlrp3 inflammasome activation has been somewhat controversial and unclear. Here the authors show calciprotein particles are taken up by myeloid cells via calcium-sensing receptor-dependent macropinocytosis in response to high levels of extracellular Ca2+ and this pathway might be critical to inflammatory conditions.

Elisabeth Jäger
Supriya Murthy
Ulf Wagner
ResearchOpen Access25 Aug 2020
Nature Communications

Volume: 11, P: 1-17
Interim FDG-PET analysis to identify patients with aggressive non-Hodgkin lymphoma who benefit from treatment intensification: a post-hoc analysis of the PETAL trial

Robert Seifert
David Kersting
Michael Schäfers
ResearchOpen Access14 Oct 2022
Leukemia

Volume: 36, P: 2845-2852
Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation

Transcription factor TFIIIC plays roles in Pol III transcription and in chromatin organization. CryoEM structure of the yeast TFIIIC subcomplex τA, a negative stain reconstruction of τA bound to the TFIIIB subunits Brf1 and TBP and accompanying biochemistry suggest how τA achieves positioning of TFIIIB upstream of the TSS and remodeling of the TFIIIC complex during assembly of TFIIIB.

Matthias K. Vorländer
Anna Jungblut
Christoph W. Müller
ResearchOpen Access30 Sept 2020
Nature Communications

Volume: 11, P: 1-12
Infection fatality rate of SARS-CoV2 in a super-spreading event in Germany

Here the authors present a SARS-CoV2 seroepidemiological observational study from a random, household-based study population in a small town in Germany, showing the effect of a super-spreading event on infection rate, severity, and potentially infection fatality rate.

Hendrik Streeck
Bianca Schulte
Gunther Hartmann
ResearchOpen Access17 Nov 2020
Nature Communications

Volume: 11, P: 1-12
Diagnostic accuracy and clinical implications of robotic assisted MRI-US fusion guided target saturation biopsy of the prostate

Christian Wetterauer
Pawel Trotsenko
Hans Helge Seifert
ResearchOpen Access12 Oct 2021
Scientific Reports

Volume: 11, P: 1-6
Insights into the accuracy of social scientists’ forecasts of societal change

How accurate are social scientists in predicting societal change, and what processes underlie their predictions? Grossmann et al. report the findings of two forecasting tournaments. Social scientists’ forecasts were on average no more accurate than those of simple statistical models.

Igor Grossmann
Amanda Rotella
Tom Wilkening
Research09 Feb 2023
Nature Human Behaviour

Volume: 7, P: 484-501
Antibiotic prophylaxis may not be necessary in patients with asymptomatic bacteriuria undergoing intradetrusor onabotulinumtoxinA injections for neurogenic detrusor overactivity

Lorenz Leitner
Ulla Sammer
Thomas M. Kessler
ResearchOpen Access12 Sept 2016
Scientific Reports

Volume: 6, P: 1-7
Host genome integration and giant virus-induced reactivation of the virophage mavirus

Endogenous viral elements found in a marine protozoan have a function in defence against infection by giant viruses.

Matthias G. Fischer
Thomas Hackl
Research07 Dec 2016
Nature

Volume: 540, P: 288-291
Proliferation of human malignant astrocytomas is dependent on Ras activation

Abhijit Guha
Matthias M Feldkamp
Anthony Pawson
Research04 Dec 1997
Oncogene

Volume: 15, P: 2755-2765
Laser melting manufacturing of large elements of lunar regolith simulant for paving on the Moon

Juan-Carlos Ginés-Palomares
Miranda Fateri
Jens Günster
ResearchOpen Access12 Oct 2023
Scientific Reports

Volume: 13, P: 1-11
The impact of Atlantic Multidecadal Variability on Baltic Sea temperatures limited to winter

Florian Börgel
Matthias Gröger
Leonard Borchert
ResearchOpen Access08 Jun 2023
npj Climate and Atmospheric Science

Volume: 6, P: 1-9
Influence of the hierarchical architecture of multi-core iron oxide nanoflowers on their magnetic properties

Stefan Neumann
Laura Kuger
David Rafaja
ResearchOpen Access07 Apr 2023
Scientific Reports

Volume: 13, P: 1-14
On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

Damaged erythrocytes accumulate in various pathological conditions, such as hemolytic anemia, anemia of inflammation, and sickle cell disease. In mice challenged with damaged erythorcytes, a monocyte subset migrates to the liver (but not to the spleen), and this subset differentiates into a transient macrophage population that removes the damaged erythrocytes, thus preventing organ damage.

Igor Theurl
Ingo Hilgendorf
Filip K Swirski
Research18 Jul 2016
Nature Medicine

Volume: 22, P: 945-951
Fission of Lipid-Vesicles by Membrane Phase Transitions in Thermal Convection

Patrick W. Kudella
Katharina Preißinger
Christoph Westerhausen
ResearchOpen Access11 Dec 2019
Scientific Reports

Volume: 9, P: 1-11
Three-dimensional Aerographite-GaN hybrid networks: Single step fabrication of porous and mechanically flexible materials for multifunctional applications

Arnim Schuchardt
Tudor Braniste
Ion Tiginyanu
ResearchOpen Access06 Mar 2015
Scientific Reports

Volume: 5, P: 1-8
Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastases

Theresa Kraft
Konrad Grützmann
Michael Seifert
ResearchOpen Access09 Jan 2023
Scientific Reports

Volume: 13, P: 1-18
Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy

Theo Lorenzini
Bruno L. Cadilha
Sebastian Kobold
ResearchOpen Access04 Jul 2023
British Journal of Cancer

Volume: 129, P: 696-705
Impact of the selective A2_AR and A2_BR dual antagonist AB928/etrumadenant on CAR T cell function

Matthias Seifert
Mohamed-Reda Benmebarek
Sebastian Kobold
ResearchOpen Access20 Oct 2022
British Journal of Cancer

Volume: 127, P: 2175-2185
Measuring unbiased metatranscriptomics in suboxic waters of the central Baltic Sea using a new in situ fixation system

Janie Feike
Klaus Jürgens
Matthias Labrenz
Research21 Jul 2011
The ISME Journal

Volume: 6, P: 461-470
A modular and controllable T cell therapy platform for acute myeloid leukemia

Mohamed-Reda Benmebarek
Bruno L. Cadilha
Sebastian Kobold
ResearchOpen Access07 Jan 2021
Leukemia

Volume: 35, P: 2243-2257
Multidecadal climate variability dominated past trends in the water balance of the Baltic Sea watershed

H. E. Markus Meier
Leonie Barghorn
Hagen Radtke
ResearchOpen Access05 Jun 2023
npj Climate and Atmospheric Science

Volume: 6, P: 1-9

Search

A stable backbone for the fungi

Nicotinamide modulates gut microbial metabolic potential and accelerates recovery in mild-to-moderate COVID-19

Author Correction: NeoR, a near-infrared absorbing rhodopsin

COVID-19 death toll predictions show that triggering counterfactual thinking deteriorates judgmental performance

The LDL receptor pathway delivers arachidonic acid for eicosanoid formation in cells stimulated by platelet-derived growth factor

NeoR, a near-infrared absorbing rhodopsin

Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia

Therapeutic targeting of ATR in alveolar rhabdomyosarcoma

T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours

Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification

Alternative splicing regulates stochastic NLRP3 activity

Author Correction: Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification

Antiviral signalling by a cyclic nucleotide activated CRISPR protease

Calcium-sensing receptor-mediated NLRP3 inflammasome response to calciprotein particles drives inflammation in rheumatoid arthritis

Interim FDG-PET analysis to identify patients with aggressive non-Hodgkin lymphoma who benefit from treatment intensification: a post-hoc analysis of the PETAL trial

Structure of the TFIIIC subcomplex τA provides insights into RNA polymerase III pre-initiation complex formation

Infection fatality rate of SARS-CoV2 in a super-spreading event in Germany

Diagnostic accuracy and clinical implications of robotic assisted MRI-US fusion guided target saturation biopsy of the prostate

Insights into the accuracy of social scientists’ forecasts of societal change

Antibiotic prophylaxis may not be necessary in patients with asymptomatic bacteriuria undergoing intradetrusor onabotulinumtoxinA injections for neurogenic detrusor overactivity

Host genome integration and giant virus-induced reactivation of the virophage mavirus

Proliferation of human malignant astrocytomas is dependent on Ras activation

Laser melting manufacturing of large elements of lunar regolith simulant for paving on the Moon

The impact of Atlantic Multidecadal Variability on Baltic Sea temperatures limited to winter

Influence of the hierarchical architecture of multi-core iron oxide nanoflowers on their magnetic properties

On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver

Fission of Lipid-Vesicles by Membrane Phase Transitions in Thermal Convection

Three-dimensional Aerographite-GaN hybrid networks: Single step fabrication of porous and mechanically flexible materials for multifunctional applications

Patient-specific identification of genome-wide DNA-methylation differences between intracranial and extracranial melanoma metastases

Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy

Impact of the selective A2_AR and A2_BR dual antagonist AB928/etrumadenant on CAR T cell function

Measuring unbiased metatranscriptomics in suboxic waters of the central Baltic Sea using a new in situ fixation system

A modular and controllable T cell therapy platform for acute myeloid leukemia

Multidecadal climate variability dominated past trends in the water balance of the Baltic Sea watershed

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