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Showing 1–3 of 3 results
Advanced filters: Author: Meghan Zubradt Clear advanced filters

  • DMS-MaPseq enables genome-wide and target-specific RNA secondary structure probing of even rare or heterogeneously structured RNAs in vivo and was used to study structure involved in translation regulation as well as nascent transcripts.

    • Meghan Zubradt
    • Paromita Gupta
    • Silvi Rouskin
    Research
    Nature Methods
    Volume: 14, P: 75-82

  • Understanding how RNA structure influences its function has been hampered by a lack of approaches that can accurately quantify RNA structure in vivo; here, RNA structure is revealed on a global scale and with nucleotide-level resolution, showing that there is less structure within cells than expected from in vitro and in silico analyses.

    • Silvi Rouskin
    • Meghan Zubradt
    • Jonathan S. Weissman
    Research
    Nature
    Volume: 505, P: 701-705