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Showing 1–2 of 2 results
Advanced filters: Author: Melanie Allram Clear advanced filters

  • Targeting a non-natural micropeptide ‘killswitch’ to several biomolecular condensates altered condensate compositions and revealed condensate functions in human cells

    • Yaotian Zhang
    • Ida Stöppelkamp
    • Denes Hnisz
    ResearchOpen Access
    Nature
    P: 1-10

  • The epigenetic and transcriptional roles of Nucleoporin 98 (NUP98) fusion oncoproteins in driving pediatric acute myeloid leukemia (AML) remain to be explored. Here, the authors identify a core set of genes regulated by NUP98::KDM5A and suggest CDK12 as a potential therapeutic vulnerability.

    • Selina Troester
    • Thomas Eder
    • Florian Grebien
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-21