Here, Song and Li et al. show that autophagy-related 8 (Atg8) recruits Atg1 to the surface of autophagosomes to coordinate membrane expansion of the autophagy machinery. Artificial tethering of the Atg1 kinase ___domain to autophagosomal membranes boosts autophagy in multiple species.
- Jing-Zhen Song
- Hui Li
- Zhiping Xie