Nature Search

Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China

The genomic epidemiology of Acinetobacter baumannii, which is rising in virulence and multidrug resistance, was explored. This study examined bloodstream infection isolates from Chinese patients in 2011–2021, revealing increased genetic diversity and dominance of highly virulent ST208.

Qixia Luo
Mengru Chang
Yonghong Xiao
ResearchOpen Access14 Apr 2025
Nature Communications

Volume: 16, P: 1-17
Orthosteric and allosteric modulation of human HCAR2 signaling complex

Hydroxycarboxylic acid receptor 2 (HCAR2) has been implicated in cardiovascular and neuroinflammatory diseases. Here, the authors present cryo-EM structures of HCAR2-Gi1 complexes bound to different ligands and provide insights into the mechanisms of both orthosteric and allosteric modulation of HCAR2.

Chunyou Mao
Mengru Gao
Yan Zhang
ResearchOpen Access22 Nov 2023
Nature Communications

Volume: 14, P: 1-10
Reversible multivalent carrier redox exceeding intercalation capacity boundary

Aqueous batteries with multivalent-ion storage chemistry offer higher theoretical capacity than monovalent-ion. Here, authors report divalent copper intercalation into vanadium disulfide with additional copper redox that provides higher capacity than intercalation transition metal redox alone.

Yuanhe Sun
Rui Qi
Daming Zhu
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-11
Sphingosine kinase 2 deficiency impairs VLDL secretion by inhibiting mTORC2 phosphorylation and activating chaperone-mediated autophagy

Shuangshuang Zhang
Gaoxiang Li
Hong Zhou
ResearchOpen Access08 Apr 2025
Cell Death & Differentiation

P: 1-14
The global patent landscape of mRNA for diagnosis and therapy

The COVID-19 pandemic brought mRNA vaccines to market in a short period, pointing the entire drug development field in the direction of mRNA treatment.

Mengru Lyu
Jiyuan Chen
Yuan Gao
Comments & Opinion12 Sept 2023
Nature Biotechnology

Volume: 41, P: 1193-1199
Phosphorylated FOXQ1, a novel substrate of JNK1, inhibits sorafenib-induced ferroptosis by activating ETHE1 in hepatocellular carcinoma

Yiwei Liu
Ke Shao
Xiaofeng Wu
ResearchOpen Access05 Jun 2024
Cell Death & Disease

Volume: 15, P: 1-14
Association of dietary patterns and endoscopic gastric mucosal atrophy in an adult Chinese population

Song Lin
Tao Gao
Aiguo Ma
ResearchOpen Access12 Nov 2019
Scientific Reports

Volume: 9, P: 1-9
The cardioprotective effects of the new crystal form of puerarin in isoproterenol-induced myocardial ischemia rats based on metabolomics

Yuzhi Zhou
Mengru Li
Guanhua Du
ResearchOpen Access20 Oct 2020
Scientific Reports

Volume: 10, P: 1-18
Single-cell transcriptome analysis reveals cellular heterogeneity in the ascending aortas of normal and high-fat diet-fed mice

Hao Kan
Ka Zhang
Xin Ma
ResearchOpen Access21 Sept 2021
Experimental & Molecular Medicine

Volume: 53, P: 1379-1389
Systematic analysis of gut microbiota in pregnant women and its correlations with individual heterogeneity

Hongling Yang
Ruochun Guo
Chunyan Zhu
ResearchOpen Access11 Sept 2020
npj Biofilms and Microbiomes

Volume: 6, P: 1-12
Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity

Le Zheng
Tingting Yang
Xiaoyun Ji
CorrespondenceOpen Access06 Nov 2023
Cell Research

Volume: 34, P: 80-83

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Genomic epidemiology and phylodynamics of Acinetobacter baumannii bloodstream isolates in China

Orthosteric and allosteric modulation of human HCAR2 signaling complex

Reversible multivalent carrier redox exceeding intercalation capacity boundary

Sphingosine kinase 2 deficiency impairs VLDL secretion by inhibiting mTORC2 phosphorylation and activating chaperone-mediated autophagy

The global patent landscape of mRNA for diagnosis and therapy

Phosphorylated FOXQ1, a novel substrate of JNK1, inhibits sorafenib-induced ferroptosis by activating ETHE1 in hepatocellular carcinoma

Association of dietary patterns and endoscopic gastric mucosal atrophy in an adult Chinese population

The cardioprotective effects of the new crystal form of puerarin in isoproterenol-induced myocardial ischemia rats based on metabolomics

Single-cell transcriptome analysis reveals cellular heterogeneity in the ascending aortas of normal and high-fat diet-fed mice

Systematic analysis of gut microbiota in pregnant women and its correlations with individual heterogeneity

Cryo-EM structures of human SID-1 transmembrane family proteins and implications for their low-pH-dependent RNA transport activity

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