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Stable coating of filters with a thin liquid layer enhances adhesion of airborne particulates while maintaining high air permeability, resulting in longer lifetimes and higher efficiency of these filters.

Addressing the stability challenges from metal electrodes/perovskite components chemical interactions is essential for high-performance perovskite solar cells. Here, authors design a bilayer polymer buffer to mitigate metal/ion interdiffusion, realizing a certified efficiency of 26.46%.

This work demonstrates an efficient electrochemical exfoliation approach to achieve high recovery rate for few-layered halogenated MXenes by leveraging gaseous propylene molecules as ‘physical scissors’, to enable advanced tribovoltaic nanogenerators.

A three-site Kitaev chain, constructed from three semiconducting quantum dots coupled by superconducting segments in a hybrid InSb/Al nanowire, shows enhanced robustness of edge zero-energy modes against variations in the coupling strengths or electrochemical potentials compared with a chain containing only two quantum dots.

An artificial Kitaev chain is realized by engineering three coupled quantum dots in a two-dimensional electron gas, which enables the manipulation and observation of both the edge and bulk states.

To improve the tolerance of perovskite solar cells against high temperatures and temperature variations, Dong et al. covalently cross-link two molecules in the charge transport layer to strengthen adhesion with the perovskite layer.

Understanding water transport through nanochannels is central to biology, separations and clean water. Here, the authors show transport of water vapor through Angstrom-scale pores (~2.8–6.6 Å in diameter) in atomically thin graphene membranes is orders of magnitude faster than liquid water, due to permeation occurring in different flow regimes.

Though literature reports metal halide perovskite epitaxial growth on various substrates, controlling film growth for device applications remains a challenge. Here, the authors report kinetic-controlled growth of halide perovskite thin films on various substrates via layered perovskite templates.

Laser spectroscopy measurements of the fermium isotopic chain show a smooth trend in the nuclear size of heavy actinide elements, and diminishing shell effects on the size evolution compared with lighter nuclei.

A Kitaev chain formed by two quantum dots coupled via a superconductor support the so-called poor man’s Majorana bound states. Here, the authors form a minimal Kitaev chain using Yu-Shiba-Rusinov states and show that the resulting bound states are more robust than in the case of unproximitized quantum dots.

A liquid metal printing technique can be used to create monolayer and bilayer indium tin oxide, with the bilayer samples offering a transparency above 99.3% and a sheet resistance as low as 5.4 kΩ □⁻¹.

Retrotransposons are repetitive sequences in the genome that can amplify themselves and whose activity has been linked to age-related pathologies. Here, Van Meter et al.report that the histone deacetylase SIRT6 represses activity of the L1 retrotransposon by ribosylating the nuclear corepressor protein, KAP1.

Deciphering the origin, age, and composition of deep marine organic carbon remains a challenge for understanding the dynamics of the marine carbon cycle. Here, the authors identify (sub)micron-sized graphite emanating from both high and low temperature hydrothermal vents along the East Pacific Rise, and suggest graphite is a source of old carbon in the deep ocean.

The usual light conditions used in laboratories fail to mimic natural conditions. Here, by slightly modifying red/far-red ratios and temperature dynamics, the authors are able to faithfully reproduce natural spring flowering times and variation of the FT gene.

Nitrospira inopinata and probably most other comammox microorganisms can grow on the non-conventional substrate guanidine as the sole source of energy, reductant and nitrogen.

A co-adsorbent is used to achieve a uniform self-assembled phosphonic acid monolayer on a textured substrate, leading to more efficient inverted perovskite solar cells.

Free-living microorganisms regulate the fluidity of their membranes by adapting lipid composition to environmental temperatures. Here, the authors quantify lipid biosynthetic enzymes and metabolic intermediates to provide a quantitative description of how the bacterium Escherichia coli maintains constant membrane fluidity after a temperature shock.

A high-resolution, global atlas of mortality of children under five years of age between 2000 and 2017 highlights subnational geographical inequalities in the distribution, rates and absolute counts of child deaths by age.

Intermediate-length repeat expansions in ATXN-2 are the strongest genetic risk factor for ALS. Here, the authors combine patient-derived motor neurons and organoids with mouse models to dissect the pathogenic effects of ATXN2 intermediate expansions.

Using experimental communities of grassland species, this study shows that drought-exposure history can accelerate recovery from subsequent drought through increased niche complementarity between species. This transgenerational effect may enhance the sustainability of biodiversity and ecosystem functioning in a future with more frequent droughts.

Intravitreal administration of the antisense oligonucleotide sepofarsen in patients with Leber congenital amaurosis type 10 showed a manageable safety profile, ocular adverse events being dose dependent, and achieved meaningful improvements of visual function.

Suppressing surface Cs⁺ accumulation in methylammonium-free α-FA_1−xCs_xPbI₃ perovskite with an intermediate phase-assisted strategy enables high-efficiency and thermally stable photovoltaics.

Light-sensitive regulators of protein kinases could offer valuable insights into intracellular signalling. Here the authors design an optogenetic inhibitor of c-Jun N-terminal kinase (JNK) and show evidence for resonance in JNK signalling circuits in neurons, and use the same design principle to develop an inhibitor for p38MAPK.

The instability of contact layers for perovskite solar cells under operating conditions limits the deployment of the technology. Now, Lin et al. develop a Cu–Ni electrode sandwiched between in situ-grown graphene protective layers, enabling solar cells with improved stability under light, humidity and high temperature.

Seagrass-mediated dissolution and reprecipitation of carbonate sediments have consequences for sedimentary organic matter cycling in terms of sulfur content and coupling to dissolved pools, according to an analysis using inorganic stable isotopes combined with molecular characterization.

Metabolite extraction with organic solvents is assumed to remove/denature proteins. Here, the authors uncover a vast landscape of >1,000 proteins in metabolite extracts. These proteins can retain catalytic activity and drive post-extraction metabolite changes, obscuring biological interpretation.

How small-bodied hominins in southeast Asia became so small ~60 thousand years ago is unclear. Here, the authors present hominin remains dated to 700 thousand years ago with even smaller body size, suggesting early evolution and maintained small size in the region.’

One of the key challenges 2D materials still face is their uniform wafer-scale deposition. Here, the authors present a deposition method for post-transition metal dichalcogenides, based on transformation of an ultra-thin oxide layer on the surface of liquid elemental gallium onto an oxide-coated substrate.

Current media for neuronal cell and organoid cultures are suboptimal for functional imaging and optogenetics experiments, owing to phototoxicity and unphysiological performance. Here the authors formulate an optimised neuronal medium to support live cell imaging and electrophysiological activity.

Lifespan can be affected by both physiological ageing and specific sets of pathologies associated with old age. Here the authors report a resource of large-scale cross-sectional phenotyping of aging male mice at different time points to analyse a large set of phenotypes and molecular markers, including during genetic and diet interventions affecting lifespan.

The authors show that dynamics of protein phosphorylation in the vertebrate cell cycle is largely attributable to CDK-mediated regulation of intrinsically disordered proteins that are involved in biomolecular condensate formation.

Two-dimensional van der Waals heterostructures are of interest due to their unique interlayer coupling and optoelectronic properties. Here authors develop a Langmuir-Blodgett method to organize charge transfer molecular heterostructures with externally tunable conductance and capacitance and broadband photoresponse.

The development of highly water-permeable membranes is key for the treatment of high salinity waters. Here the authors enhance the water permeability of a metal-organic framework nanoporous membrane via an intra-crystalline defect engineering strategy.

A wireless ‘smart’ bandage stimulates wound healing.

The presence of organic solvents in solar cells has hindered the application of devices, especially in flexible cells. Now, by mixing three solid salts, a solvent-free liquid electrolyte for dye-sensitized solar cells has been discovered that shows both excellent efficiency and stability.

Aromatic two-dimensional covalent organic frameworks (2D COFs) are hailed as candidates for electronic and optical devices, yet only few applications were demonstrated. Here, the authors show a triazine based COF with UV/VIS real-time response and increase in bulk conductivity to HCl vapour as a chemical trigger.

The effect of soil structure is not included in most Earth System Models. The authors here introduce and evaluate the consequences at local and global scale of modifying hydraulic properties of soils in response to biological activity—a process significantly changing soil structure.

Pompe disease is currently treated with enzyme replacement therapy (ERT) with recombinant human acid alpha-glucosidase (GAA). Here, the authors show hepatic-directed gene therapy with AAV vectors enhances GAA bioavailability compared with ERT, resulting in improved rescue of the disease phenotype in mice and broad enzyme distribution in mice and non-human primates.

Lead-free perovskite light-emitting diodes (LEDs) prepared using tautomeric mixture coordination provide improved ordering in the crystal structure, reduced recombination and enhanced exciton binding energy compared with lead-containing perovskite-based LEDs.

In most cancers, mutations that lead to oncogene activation and tumor suppressor inactivation synergize to promote tumorigenesis. However, in neuroblastomas, MYCN amplification and ATRX mutations are mutually exclusive and incompatible.

Springtails are omnipresent soil arthropods, vital for ecosystems. In the first global assessment of springtails, this study shows a 20-fold biomass difference between the tundra and the tropics, with distinct temperature-related patterns for diversity and metabolism that suggest climate change may restructure the functioning of soil biodiversity.

Medulloblastoma is the most common malignant brain tumour in children; having assembled over 1,000 samples the authors report that somatic copy number aberrations are common in medulloblastoma, in particular a tandem duplication of SNCAIP, a gene associated with Parkinson’s disease, which is restricted to subgroup 4α, and translocations of PVT1, which are restricted to Group 3.

PhAST is a technology for establishing de novo or modulating synaptic transmission in a light-dependent manner in C. elegans. By combining a calcium-dependent luciferase on pre-synapses with channelrhodopsin on post-synapses, light serves as a synthetic neurotransmitter.

The genome of the biofuel crop switchgrass (Panicum virgatum) reveals climate–gene–biomass associations that underlie adaptation in nature and will facilitate improvements of the yield of this crop for bioenergy production.