Nature Search

Striatal dopamine D2/D3 receptor regulation of human reward processing and behaviour

Osugo et al show in healthy humans that sustained dopamine D2/D3 receptor antagonism impairs motivated behaviour, hedonic experience, and emotional expression, and that this is related to blunted striatal reward response following D2/D3 antagonism.

Martin Osugo
Matthew B. Wall
Oliver D. Howes
ResearchOpen Access21 Feb 2025
Nature Communications

Volume: 16, P: 1-13
Antipsychotics cause reversible structural brain changes within one week

Pierluigi Selvaggi
Martin Osugo
Oliver D. Howes
Research07 May 2025
Neuropsychopharmacology

Volume: 50, P: 1275-1283
Mapping brain structural differences and neuroreceptor correlates in Parkinson’s disease visual hallucinations

Visual hallucinations are a prevalent symptom of Parkinson’s disease. Here the authors use a structural mega-analysis to show cortical regions and networks involved in visual hallucinations and associations with receptor density maps.

Miriam Vignando
Dominic ffytche
Mitul A. Mehta
ResearchOpen Access26 Jan 2022
Nature Communications

Volume: 13, P: 1-16
Author Correction: Associations between dimensions of behaviour, personality traits, and mental-health during the COVID-19 pandemic in the United Kingdom

Adam Hampshire
Peter J. Hellyer
Samuel R. Chamberlain
Amendments and CorrectionsOpen Access16 Aug 2021
Nature Communications

Volume: 12, P: 1-4
Associations between dimensions of behaviour, personality traits, and mental-health during the COVID-19 pandemic in the United Kingdom

The COVID-19 pandemic has affected people’s health and well-being. Here, the authors characterize self-reported impact of the pandemic (positive and negative) at a large scale in the United Kingdom, and show variance among individual circumstances.

Adam Hampshire
Peter J. Hellyer
Samuel R. Chamberlain
ResearchOpen Access16 Jul 2021
Nature Communications

Volume: 12, P: 1-15
Author Correction: Mapping brain structural differences and neuroreceptor correlates in Parkinson’s disease visual hallucinations

Miriam Vignando
Dominic ffytche
Mitul A. Mehta
Amendments and CorrectionsOpen Access15 Feb 2022
Nature Communications

Volume: 13, P: 1
Where Do We Go from Here? The Importance of Initial Values

Mitul A Mehta
Correspondence23 Apr 2002
Neuropsychopharmacology

Volume: 27, P: 879-880
Pattern Classification of Working Memory Networks Reveals Differential Effects of Methylphenidate, Atomoxetine, and Placebo in Healthy Volunteers

Andre F Marquand
Sara De Simoni
Mitul A Mehta
ResearchOpen Access23 Feb 2011
Neuropsychopharmacology

Volume: 36, P: 1237-1247
Nature or Nurture? Determining the Heritability of Human Striatal Dopamine Function: an [18F]-DOPA PET Study

Paul R A Stokes
Paul Shotbolt
Oliver D Howes
Research24 Oct 2012
Neuropsychopharmacology

Volume: 38, P: 485-491
The Effects of The COMT val^108/158met Polymorphism on BOLD Activation During Working Memory, Planning, and Response Inhibition: A Role for The Posterior Cingulate Cortex?

Paul R A Stokes
Rebecca A Rhodes
Mitul A Mehta
Research08 Dec 2010
Neuropsychopharmacology

Volume: 36, P: 763-771
Rapid white matter changes in children with conduct problems during a parenting intervention

Suzanne O’ Brien
Arjun Sethi
Michael C. Craig
ResearchOpen Access04 Nov 2023
Translational Psychiatry

Volume: 13, P: 1-9
Preliminary evidence that ketamine alters anterior cingulate resting-state functional connectivity in depressed individuals

Laith Alexander
Peter C. T. Hawkins
Carlos A. Zarate Jr
ResearchOpen Access01 Dec 2023
Translational Psychiatry

Volume: 13, P: 1-10
Molecular-enriched functional connectivity in the human brain using multiband multi-echo simultaneous ASL/BOLD fMRI

Ottavia Dipasquale
Alexander Cohen
Yang Wang
ResearchOpen Access20 Jul 2023
Scientific Reports

Volume: 13, P: 1-11
Altered dynamics of the prefrontal networks are associated with the risk for postpartum psychosis: a functional magnetic resonance imaging study

Fabio Sambataro
Giulia Cattarinussi
Paola Dazzan
ResearchOpen Access12 May 2021
Translational Psychiatry

Volume: 11, P: 1-11
Methylphenidate (‘Ritalin’) can Ameliorate Abnormal Risk-Taking Behavior in the Frontal Variant of Frontotemporal Dementia

Shibley Rahman
Trevor W Robbins
Barbara J Sahakian
Research07 Sept 2005
Neuropsychopharmacology

Volume: 31, P: 651-658
Unravelling the effects of methylphenidate on the dopaminergic and noradrenergic functional circuits

Ottavia Dipasquale
Daniel Martins
Mara Cercignani
Research30 May 2020
Neuropsychopharmacology

Volume: 45, P: 1482-1489
Psilocybin and MDMA reduce costly punishment in the Ultimatum Game

Anthony S. Gabay
Robin L. Carhart-Harris
Mitul A. Mehta
ResearchOpen Access29 May 2018
Scientific Reports

Volume: 8, P: 1-9
Cerebral blood flow predicts differential neurotransmitter activity

Juergen Dukart
Štefan Holiga
Fabio Sambataro
ResearchOpen Access06 Mar 2018
Scientific Reports

Volume: 8, P: 1-11
Brain structure in women at risk of postpartum psychosis: an MRI study

Montserrat Fusté
Astrid Pauls
Paola Dazzan
ResearchOpen Access18 Dec 2017
Translational Psychiatry

Volume: 7, P: 1-9
Evidence for similar structural brain anomalies in youth and adult attention-deficit/hyperactivity disorder: a machine learning analysis

Yanli Zhang-James
Emily C. Helminen
Stephen V. Faraone
ResearchOpen Access01 Feb 2021
Translational Psychiatry

Volume: 11, P: 1-9
Opposite Effects of Δ-9-Tetrahydrocannabinol and Cannabidiol on Human Brain Function and Psychopathology

Sagnik Bhattacharyya
Paul D Morrison
Philip K McGuire
Research18 Nov 2009
Neuropsychopharmacology

Volume: 35, P: 764-774
DAT1 and COMT Effects on Delay Discounting and Trait Impulsivity in Male Adolescents with Attention Deficit/Hyperactivity Disorder and Healthy Controls

Yannis Paloyelis
Philip Asherson
Jonna Kuntsi
Research25 Aug 2010
Neuropsychopharmacology

Volume: 35, P: 2414-2426
Presynaptic 5-HT1A is Related to 5-HTT Receptor Density in the Human Brain

Subrata K Bose
Mitul A Mehta
Venkatesha Murthy
Research13 Jul 2011
Neuropsychopharmacology

Volume: 36, P: 2258-2265

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