Single-cell transcriptomics can allow detailed analyses of paediatric leukaemias. Here, the authors integrate single-cell data from 159 paediatric leukaemia and healthy bone marrow samples, identify a leukaemia-enriched gene expression signature, and develop the integrative online Paediatric Single-cell Cancer Atlas to explore and analyse this harmonised dataset.
- Hope L. Mumme
- Chenbin Huang
- Manoj Bhasin