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European Journal of Human Genetics (2)
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Showing 1–8 of 8 results

Advanced filters: Author: Nadine Andrieu Clear advanced filters

A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Breast cancer risk for BRCA1/BRCA2 mutation carriers varies depending on other genetic factors. Here, the authors perform a case-only genome-wide association study and highlight novel loci associated with breast cancer risk for BRCA1/BRCA2 mutation carriers.

Juliette Coignard
Michael Lush
Antonis C. Antoniou
ResearchOpen Access17 Feb 2021
Nature Communications

Volume: 12, P: 1-22
Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Juliette Coignard
Michael Lush
Antonis C. Antoniou
Amendments and CorrectionsOpen Access14 May 2021
Nature Communications

Volume: 12, P: 1-2
Estimating penetrance from multiple case families with predisposing mutations: extension of the ‘genotype-restricted likelihood’ (GRL) method

Bernard Bonaïti
Valérie Bonadona
Catherine Bonaïti-Pellié
Research06 Oct 2010
European Journal of Human Genetics

Volume: 19, P: 173-179
Polygenic risk scores and breast and epithelial ovarian cancer risks for carriers of BRCA1 and BRCA2 pathogenic variants

Daniel R. Barnes
Matti A. Rookus
Antonis C. Antoniou
ResearchOpen Access15 Jul 2020
Genetics in Medicine

Volume: 22, P: 1653-1666
Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity

Severe COVID-19 is characterized by hyperinflammation, and there is a need for accurate predictive biomarkers of progression. Lehuen et al. demonstrate that patients with severe COVID-19 show a dramatic loss of MAIT cells, and those that do remain are in a highly activated state.

Héloïse Flament
Matthieu Rouland
Agnès Lehuen
Research02 Feb 2021
Nature Immunology

Volume: 22, P: 322-335
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

SAMHD1 restricts the infection of dendritic cells by human immunodeficiency virus type 1. Margottin-Goguet and colleagues show that SAMHD1 limits viral DNA synthesis by hydrolyzing intracellular dNTPs.

Hichem Lahouassa
Waaqo Daddacha
Florence Margottin-Goguet
Research12 Feb 2012
Nature Immunology

Volume: 13, P: 223-228
Mutation screening of MIR146A/B and BRCA1/2 3′-UTRs in the GENESIS study

Amandine I Garcia
Monique Buisson
Sylvie Mazoyer
Research20 Jan 2016
European Journal of Human Genetics

Volume: 24, P: 1324-1329
Increased risk of breast cancer among female relatives of patients with ataxia-telangiectasia: a causal relationship?

A K d'Almeida
E Cavaciuti
N Andrieu
CorrespondenceOpen Access13 Sept 2005
British Journal of Cancer

Volume: 93, P: 730-732