RNA-binding proteins include essential regulators of microRNA (miRNA) biogenesis, turnover and activity. RNA–RNA and protein–RNA interactions are essential for post-transcriptional regulation in normal development and could be deregulated in disease. This Review highlights the implications of these complex layers of regulation in cancer initiation and progression.
- Marieke van Kouwenhove
- Martijn Kedde
- Reuven Agami
